A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 45, 2014, Pages 16017-16022

  Sood, Aditi ^a,b   Jeyaraju, Danny Vijey ^a,b   Prudent, Julien ^c   Caron, Alexandre ^d   Lemieux, Philippe ^b   McBride, Heidi May ^c   Laplante, Mathieu ^d   Tóth, Katalin ^a   Pellegrini, Luca ^a,b  

^a UNIVERSITÉ LAVAL   (Canada)

^b CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d LAVAL UNIVERSITY   (Canada)

Author keywords

Mfn2; Mitochondria; Mitochondria ER contacts; MTORC1; Opa1

Indexed keywords

CALPAIN 1; CYSTEINE PROTEINASE; GUANOSINE TRIPHOSPHATASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; MITOFUSIN 2; OPTIC ATROPHY 1 PROTEIN; UNCLASSIFIED DRUG; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; METALLOPROTEINASE; MFN2 PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN; MULTIPROTEIN COMPLEX; OMA1 PROTEIN, MOUSE; OPA1 PROTEIN (GTPASE), MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL EXPANSION; CELL ORGANELLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; CRISTAE; CYTOARCHITECTURE; ENDOPLASMIC RETICULUM MEMBRANE; FOOD INTAKE; HELA CELL LINE; IN VITRO STUDY; LIVER BIOPSY; LIVER CELL; LIVER METABOLISM; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PHOSPHOLIPID TRANSFER; POSTPRANDIAL STATE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSIENT EXPRESSION; ANIMAL; CALCIUM SIGNALING; ENDOPLASMIC RETICULUM; GENETICS; METABOLISM; PHYSIOLOGY;

ANIMALS; CALCIUM SIGNALING; ENDOPLASMIC RETICULUM; GTP PHOSPHOHYDROLASES; MALE; METALLOPROTEASES; MICE; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; MULTIPROTEIN COMPLEXES; POSTPRANDIAL PERIOD; PROTEOLYSIS; TOR SERINE-THREONINE KINASES;

EID: 84909595098     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1408061111     Document Type: Article

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