P100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 45, 2014, Pages 15946-15951

  Tao, Zhihua ^a   Fusco, Amanda ^a   Huang, De Bin ^a   Gupta, Kushol ^b   Kim, Daniel Young ^a   Ware, Carl F ^c   Van Duyne, Gregory D ^b   Ghosh, Gourisankar ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

I B; KappaBsome; NF kappa; B; Structure; Transcription

Indexed keywords

I KAPPA B; I KAPPA B DELTA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P100; UNCLASSIFIED DRUG; I KAPPA B BETA; IKAPPABGAMMA PROTEIN, HUMAN; IKAPPABNS PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; NFKB2 PROTEIN, HUMAN; NFKB2 PROTEIN, MOUSE; PEPTIDE FRAGMENT; PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; NONHUMAN; OLIGOMERIZATION; 3T3 CELL LINE; ANIMAL; CHEMISTRY; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MOUSE; PROTEIN DEGRADATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

3T3 CELLS; ANIMALS; CRYSTALLOGRAPHY, X-RAY; HUMANS; I-KAPPA B PROTEINS; MICE; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; NF-KAPPA B P52 SUBUNIT; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; PROTEOLYSIS; TRANSCRIPTION FACTORS;

EID: 84909594611     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1408552111     Document Type: Article

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