Intact protein analysis of ubiquitin in cerebrospinal fluid by multiple reaction monitoring reveals differences in alzheimers disease and frontotemporal lobar degeneration

Journal of Proteome Research

Volumn 13, Issue 11, 2014, Pages 4518-4525

  Oeckl, Patrick ^a   Steinacker, Petra ^a   Von Arnim, Christine A F ^a   Straub, Sarah ^a   Nagl, Magdalena ^a   Feneberg, Emily ^a   Weishaupt, Jochen H ^a   Ludolph, Albert C ^a   Otto, Markus ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

Alzheimers disease; amyotrophic lateral sclerosis; biomarker; cerebrospinal fluid; Creutzfeldt Jakob disease; frontotemporal lobar degeneration; mass spectrometry; MRM; Parkinsons disease; Ubiquitin

Indexed keywords

UBIQUITIN; BIOLOGICAL MARKER;

ADULT; AGED; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; FEMALE; FRONTAL VARIANT FRONTOTEMPORAL DEMENTIA; FRONTOTEMPORAL DEMENTIA; HUMAN; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; MOLECULAR WEIGHT; PARKINSON DISEASE; PRIMARY PROGRESSIVE APHASIA; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN ANALYSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; TANDEM MASS SPECTROMETRY; AREA UNDER THE CURVE; CEREBROSPINAL FLUID; COMPARATIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; APHASIA, PRIMARY PROGRESSIVE; AREA UNDER CURVE; BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; CREUTZFELDT-JAKOB SYNDROME; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; PARKINSON DISEASE; ROC CURVE; SENSITIVITY AND SPECIFICITY; SUPRANUCLEAR PALSY, PROGRESSIVE; TANDEM MASS SPECTROMETRY; UBIQUITIN;

EID: 84908888835     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5006058     Document Type: Article

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