메뉴 건너뛰기




Volumn 29, Issue 5, 2014, Pages 748-760

Evaluation of adenoviral vascular endothelial growth factor-activated chitosan/hydroxyapatite scaffold for engineering vascularized bone tissue using human osteoblasts: In vitro and in vivo studies

Author keywords

adenoviral vector; angiogenesis; Bone tissue engineering; chitosan; gene therapy; human osteoblasts; hydroxyapatite; rat; scaffold; vascular endothelial growth factor

Indexed keywords

BIOCOMPATIBILITY; BONE; CELL ENGINEERING; CHITOSAN; ENDOTHELIAL CELLS; GENE THERAPY; GREEN MANUFACTURING; HYDROXYAPATITE; OXYGEN SUPPLY; PORE SIZE; RATING; SCAFFOLDS; TISSUE; TISSUE REGENERATION;

EID: 84908869944     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328214544769     Document Type: Article
Times cited : (44)

References (45)
  • 2
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S, et al. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 1999 ; 13: 9-22
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3
  • 3
    • 84866840029 scopus 로고    scopus 로고
    • Vascularized bone tissue engineering: Approaches for potential improvement
    • Nguyen LH, Annabi N, Nikkhah M, et al. Vascularized bone tissue engineering: approaches for potential improvement. Tissue Eng Part B Rev. 2012 ; 18: 363-382
    • (2012) Tissue Eng Part B Rev , vol.18 , pp. 363-382
    • Nguyen, L.H.1    Annabi, N.2    Nikkhah, M.3
  • 4
    • 0035405650 scopus 로고    scopus 로고
    • Extensive in vivo angiogenesis from the controlled release of human vascular endothelial cell growth factor: Implications for tissue engineering and wound healing
    • Elcin YM, Dixit V, Gitnick G. Extensive in vivo angiogenesis from the controlled release of human vascular endothelial cell growth factor: implications for tissue engineering and wound healing. Artif Organs. 2001 ; 25: 558-565
    • (2001) Artif Organs , vol.25 , pp. 558-565
    • Elcin, Y.M.1    Dixit, V.2    Gitnick, G.3
  • 5
    • 33646591217 scopus 로고    scopus 로고
    • Localized angiogenesis induced by human vascular endothelial growth factor-activated PLGA sponge
    • Elcin AE, Elcin YM. Localized angiogenesis induced by human vascular endothelial growth factor-activated PLGA sponge. Tissue Eng. 2006 ; 12 (4). 959-968
    • (2006) Tissue Eng , vol.12 , Issue.4 , pp. 959-968
    • Elcin, A.E.1    Elcin, Y.M.2
  • 6
    • 0028875936 scopus 로고
    • Transfer of genes to humans: Early lessons and obstacles to success
    • Crystal RG. Transfer of genes to humans: early lessons and obstacles to success. Science. 1995 ; 270: 404-410
    • (1995) Science , vol.270 , pp. 404-410
    • Crystal, R.G.1
  • 8
    • 0037296650 scopus 로고    scopus 로고
    • Gene therapy of bone morphogenetic protein for periodontal tissue engineering
    • Jin Q, Anusaksathien O, Webb SA, et al. Gene therapy of bone morphogenetic protein for periodontal tissue engineering. J Periodontol. 2003 ; 74: 202-213
    • (2003) J Periodontol , vol.74 , pp. 202-213
    • Jin, Q.1    Anusaksathien, O.2    Webb, S.A.3
  • 9
    • 0036387166 scopus 로고    scopus 로고
    • Enhancement of bone repair with a helper-dependent adenoviral transfer of bone morphogenetic protein-2
    • Nobuhiro A, Lee Y-P, Sato M, et al. Enhancement of bone repair with a helper-dependent adenoviral transfer of bone morphogenetic protein-2. Biochem Bioph Res Co. 2002 ; 297: 523-527
    • (2002) Biochem Bioph Res Co , vol.297 , pp. 523-527
    • Nobuhiro, A.1    Lee, Y.-P.2    Sato, M.3
  • 10
    • 0029994334 scopus 로고    scopus 로고
    • Stimulation of new bone formation by direct transfer of osteogenic plasmid genes
    • Fang J, Zhu YY, Smiley E, et al. Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. Proc Natl Acad Sci USA. 1996 ; 93 (12). 5753-5758
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.12 , pp. 5753-5758
    • Fang, J.1    Zhu, Y.Y.2    Smiley, E.3
  • 11
    • 0034476939 scopus 로고    scopus 로고
    • Matrix-enabled gene transfer for cutaneous wound repair
    • Chandler LA, Ma C, Gonzalez AM, et al. Matrix-enabled gene transfer for cutaneous wound repair. Wound Repair Regen. 2000 ; 8 (6). 473-479
    • (2000) Wound Repair Regen , vol.8 , Issue.6 , pp. 473-479
    • Chandler, L.A.1    Ma, C.2    Gonzalez, A.M.3
  • 12
    • 1142275271 scopus 로고    scopus 로고
    • Delivery and protection of adenoviruses using biocompatible hydrogels for localized gene therapy
    • Schek RM, Hollister SJ, Krebsbach PH. Delivery and protection of adenoviruses using biocompatible hydrogels for localized gene therapy. Mol Ther. 2004 ; 9 (1). 130-138
    • (2004) Mol Ther , vol.9 , Issue.1 , pp. 130-138
    • Schek, R.M.1    Hollister, S.J.2    Krebsbach, P.H.3
  • 13
    • 0034786764 scopus 로고    scopus 로고
    • Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo
    • Koping-Hoggard M, Tubulekas I, Guan H, et al. Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. Gene Ther. 2001 ; 8: 1108-1121
    • (2001) Gene Ther , vol.8 , pp. 1108-1121
    • Koping-Hoggard, M.1    Tubulekas, I.2    Guan, H.3
  • 14
    • 1242314681 scopus 로고    scopus 로고
    • Uptake and cytotoxicity of chitosan molecules and nanoparticles: Effects of molecular weight and degree of deacetylation
    • Huang M, Khor E, Lim L-Y. Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharm Res. 2004 ; 21: 344-353
    • (2004) Pharm Res , vol.21 , pp. 344-353
    • Huang, M.1    Khor, E.2    Lim, L.-Y.3
  • 15
    • 77954819727 scopus 로고    scopus 로고
    • In vitro permeability enhancement in intestinal epithelial cells (Caco-2) monolayer of water soluble quaternary ammonium chitosan derivatives
    • Kowapradit J, Opanasopit P, Ngawhirunpat T, et al. In vitro permeability enhancement in intestinal epithelial cells (Caco-2) monolayer of water soluble quaternary ammonium chitosan derivatives. AAPS Pharm Sci Tech. 2010 ; 11: 497-508
    • (2010) AAPS Pharm Sci Tech , vol.11 , pp. 497-508
    • Kowapradit, J.1    Opanasopit, P.2    Ngawhirunpat, T.3
  • 16
    • 77958182219 scopus 로고    scopus 로고
    • Uptake and cytotoxicity of chitosan nanoparticles in human liver cells
    • Loh JW, Yeoh G, Saunders M, et al. Uptake and cytotoxicity of chitosan nanoparticles in human liver cells. Toxicol Appl Pharm. 2010 ; 249: 148-157
    • (2010) Toxicol Appl Pharm , vol.249 , pp. 148-157
    • Loh, J.W.1    Yeoh, G.2    Saunders, M.3
  • 17
    • 3042765720 scopus 로고    scopus 로고
    • Chitosan sponges as tissue engineering scaffolds for bone formation
    • Seo YJ, Lee JY, Park YJ, et al. Chitosan sponges as tissue engineering scaffolds for bone formation. Biotechnol Lett. 2004 ; 26: 1037-1041
    • (2004) Biotechnol Lett , vol.26 , pp. 1037-1041
    • Seo, Y.J.1    Lee, J.Y.2    Park, Y.J.3
  • 18
    • 84894178765 scopus 로고    scopus 로고
    • Bone regeneration potential of the new chitosan-based alloplastic biomaterial
    • Bojar W, Kucharska M, Ciach T, et al. Bone regeneration potential of the new chitosan-based alloplastic biomaterial. J Biomater Appl. 2014 ; 28: 1060-1068
    • (2014) J Biomater Appl , vol.28 , pp. 1060-1068
    • Bojar, W.1    Kucharska, M.2    Ciach, T.3
  • 19
    • 15244356163 scopus 로고    scopus 로고
    • Stimulation of osteoblast responses to biomimetic nanocomposites of gelatin-hydroxyapatite for tissue engineering scaffolds
    • Kim HW, Kim HE, Vehid S. Stimulation of osteoblast responses to biomimetic nanocomposites of gelatin-hydroxyapatite for tissue engineering scaffolds. Biomaterials. 2005 ; 26: 5221-5230
    • (2005) Biomaterials , vol.26 , pp. 5221-5230
    • Kim, H.W.1    Kim, H.E.2    Vehid, S.3
  • 20
    • 84886795820 scopus 로고    scopus 로고
    • Physical properties and in vitro evaluation of collagen-chitosan-calcium phosphate microparticle-based scaffolds for bone tissue regeneration
    • Zugravu MV, Smith RA, Reves BT, et al. Physical properties and in vitro evaluation of collagen-chitosan-calcium phosphate microparticle-based scaffolds for bone tissue regeneration. J Biomater Appl. 2013 ; 28: 566-579
    • (2013) J Biomater Appl , vol.28 , pp. 566-579
    • Zugravu, M.V.1    Smith, R.A.2    Reves, B.T.3
  • 21
    • 33750690201 scopus 로고    scopus 로고
    • A study on the bioactivity of chitosan/nano-hydroxyapatite composite scaffolds for bone tissue engineering
    • Kong LJ, Gao Y, Lu GY, et al. A study on the bioactivity of chitosan/nano-hydroxyapatite composite scaffolds for bone tissue engineering. Eur Polym J. 2006 ; 42: 3171-3179
    • (2006) Eur Polym J , vol.42 , pp. 3171-3179
    • Kong, L.J.1    Gao, Y.2    Lu, G.Y.3
  • 22
    • 36249008010 scopus 로고    scopus 로고
    • Effect of osteogenic induction on the in vitro differentiation of human embryonic stem cells cocultured with periodontal ligament fibroblasts
    • Inanc B, Elcin AE, Elcin YM. Effect of osteogenic induction on the in vitro differentiation of human embryonic stem cells cocultured with periodontal ligament fibroblasts. Artif Organs. 2007 ; 31 (11). 792-800
    • (2007) Artif Organs , vol.31 , Issue.11 , pp. 792-800
    • Inanc, B.1    Elcin, A.E.2    Elcin, Y.M.3
  • 23
    • 24744458412 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF-A) expression in human mesenchymal stem cells: Autocrine and paracrine role on osteoblastic and endothelial differentiation
    • Mayer H, Bertram H, Lindenmaier W, et al. Vascular endothelial growth factor (VEGF-A) expression in human mesenchymal stem cells: autocrine and paracrine role on osteoblastic and endothelial differentiation. J Cell Biochem. 2005 ; 95: 827-839
    • (2005) J Cell Biochem , vol.95 , pp. 827-839
    • Mayer, H.1    Bertram, H.2    Lindenmaier, W.3
  • 24
    • 8544255751 scopus 로고    scopus 로고
    • Modulation of in vitro angiogenesis in a three-dimensional spheroidal coculture model for bone tissue engineering
    • Wenger A, Stahl A, Weber H, et al. Modulation of in vitro angiogenesis in a three-dimensional spheroidal coculture model for bone tissue engineering. Tissue Eng. 2004 ; 10: 1536-1547
    • (2004) Tissue Eng , vol.10 , pp. 1536-1547
    • Wenger, A.1    Stahl, A.2    Weber, H.3
  • 25
    • 42649136894 scopus 로고    scopus 로고
    • In vitro osteogenic differentiation of rat mesenchymal stem cells in a microgravity bioreactor
    • Koc A, Emin N, Elcin AE, et al. In vitro osteogenic differentiation of rat mesenchymal stem cells in a microgravity bioreactor. J Bioact Compat Pol. 2008 ; 23 (3). 244-261
    • (2008) J Bioact Compat Pol , vol.23 , Issue.3 , pp. 244-261
    • Koc, A.1    Emin, N.2    Elcin, A.E.3
  • 26
    • 0142125867 scopus 로고    scopus 로고
    • Functional and morphological characteristics of bovine adrenal chromaffin cells on macroporous poly(D,L-lactide-co-glycolide) scaffolds
    • Elcin YM, Elcin AE, Pappas GD. Functional and morphological characteristics of bovine adrenal chromaffin cells on macroporous poly(D,L-lactide-co-glycolide) scaffolds. Tissue Eng. 2003 ; 9 (5). 1047-1056
    • (2003) Tissue Eng , vol.9 , Issue.5 , pp. 1047-1056
    • Elcin, Y.M.1    Elcin, A.E.2    Pappas, G.D.3
  • 27
    • 34548187969 scopus 로고    scopus 로고
    • Encapsulation and osteoinduction of human periodontal ligament fibroblasts in chitosan-hydroxyapatite microspheres
    • Inanc B, Elcin AE, Koc A, et al. Encapsulation and osteoinduction of human periodontal ligament fibroblasts in chitosan-hydroxyapatite microspheres. J Biomed Mater Res A. 2007 ; 82 (4). 917-926
    • (2007) J Biomed Mater Res A , vol.82 , Issue.4 , pp. 917-926
    • Inanc, B.1    Elcin, A.E.2    Koc, A.3
  • 28
    • 0242406985 scopus 로고    scopus 로고
    • Polymers for induction of revascularisation in the rat fascial flap: Application of vascular endothelial growth factor and pancreatic cell lines
    • Linn T, Erb D, Schneider D, et al. Polymers for induction of revascularisation in the rat fascial flap: application of vascular endothelial growth factor and pancreatic cell lines. Cell Transplant. 2003 ; 12: 769-778
    • (2003) Cell Transplant , vol.12 , pp. 769-778
    • Linn, T.1    Erb, D.2    Schneider, D.3
  • 29
    • 0003484314 scopus 로고
    • Cambridge, New York: Cambridge University Press;
    • Mead R The design of experiments. Cambridge, New York: Cambridge University Press ; 1988 :
    • (1988) The Design of Experiments
    • Mead, R.1
  • 30
    • 35348883223 scopus 로고    scopus 로고
    • Microvessel-like structures from outgrowth endothelial cells from human peripheral blood in 2-dimensional and 3-dimensional co-cultures with osteoblastic lineage cells
    • Fuchs S, Hofmann A, Kirkpatrick CJ. Microvessel-like structures from outgrowth endothelial cells from human peripheral blood in 2-dimensional and 3-dimensional co-cultures with osteoblastic lineage cells. Tissue Eng. 2007 ; 13: 2577-2588
    • (2007) Tissue Eng , vol.13 , pp. 2577-2588
    • Fuchs, S.1    Hofmann, A.2    Kirkpatrick, C.J.3
  • 31
    • 79551574175 scopus 로고    scopus 로고
    • Bone formation and neovascularization mediated by mesenchymal stem cells and endothelial cells in critical-sized calvarial defects
    • Koob S, Torio-Padron N, Stark B, et al. Bone formation and neovascularization mediated by mesenchymal stem cells and endothelial cells in critical-sized calvarial defects. Tissue Eng Part A. 2011 ; 17 (3-4). 311-321
    • (2011) Tissue Eng Part A , vol.17 , Issue.34 , pp. 311-321
    • Koob, S.1    Torio-Padron, N.2    Stark, B.3
  • 32
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber HP, Vu TH, Ryan AM, et al. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med. 1999 ; 5: 623-628
    • (1999) Nat Med , vol.5 , pp. 623-628
    • Gerber, H.P.1    Vu, T.H.2    Ryan, A.M.3
  • 33
    • 0037162547 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
    • Street J, Bao M, deGuzman L, et al. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci USA. 2002 ; 99: 9656-9661
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9656-9661
    • Street, J.1    Bao, M.2    Deguzman, L.3
  • 34
    • 0033978147 scopus 로고    scopus 로고
    • AAV vectors: Is clinical success on the horizon?
    • Monahan PE, Samulski RJ. AAV vectors: is clinical success on the horizon?. Gene Therapy. 2000 ; 7: 24-30
    • (2000) Gene Therapy , vol.7 , pp. 24-30
    • Monahan, P.E.1    Samulski, R.J.2
  • 35
    • 14344276590 scopus 로고    scopus 로고
    • An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus
    • Maione D, Della-Rocca C, Giannetti P, et al. An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus. Proc Natl Acad Sci USA. 2001 ; 98: 5986-5991
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5986-5991
    • Maione, D.1    Della-Rocca, C.2    Giannetti, P.3
  • 36
    • 0033865751 scopus 로고    scopus 로고
    • Immune response to recombinant adenovirus in humans: Capsid components from viral input are targets for vector-specific cytotoxic T lymphocytes
    • Molinier-Frenkel V, Gahery-Segard H, Mehtali M, et al. Immune response to recombinant adenovirus in humans: capsid components from viral input are targets for vector-specific cytotoxic T lymphocytes. J Virol. 2000 ; 74: 7678-7682
    • (2000) J Virol , vol.74 , pp. 7678-7682
    • Molinier-Frenkel, V.1    Gahery-Segard, H.2    Mehtali, M.3
  • 37
    • 0025848772 scopus 로고
    • Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo
    • Rosenfeld MA, Siegfried W, Yoshimura K, et al. Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo. Science. 1991 ; 252: 431-434
    • (1991) Science , vol.252 , pp. 431-434
    • Rosenfeld, M.A.1    Siegfried, W.2    Yoshimura, K.3
  • 38
    • 33646063186 scopus 로고    scopus 로고
    • Novel chitosan/collagen scaffold containing transforming growth factor-b1 DNA for periodontal tissue engineering
    • Zhang Y, Cheng X, Wang J, et al. Novel chitosan/collagen scaffold containing transforming growth factor-b1 DNA for periodontal tissue engineering. Biochem Bioph Res Co. 2006 ; 344: 362-369
    • (2006) Biochem Bioph Res Co , vol.344 , pp. 362-369
    • Zhang, Y.1    Cheng, X.2    Wang, J.3
  • 39
    • 0035999776 scopus 로고    scopus 로고
    • Preparation and histological evaluation of biomimetic three-dimensional hydroxyapatite/chitosan-gelatin network composite scaffolds
    • Zhao F, Yin Y, Lu WW, et al. Preparation and histological evaluation of biomimetic three-dimensional hydroxyapatite/chitosan-gelatin network composite scaffolds. Biomaterials. 2002 ; 23: 3227-3234
    • (2002) Biomaterials , vol.23 , pp. 3227-3234
    • Zhao, F.1    Yin, Y.2    Lu, W.W.3
  • 40
    • 17844400927 scopus 로고    scopus 로고
    • Porosity of 3D biomaterial scaffolds and osteogenesis
    • Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials. 2005 ; 26: 5474-5491
    • (2005) Biomaterials , vol.26 , pp. 5474-5491
    • Karageorgiou, V.1    Kaplan, D.2
  • 41
    • 64249143427 scopus 로고    scopus 로고
    • Biomimetic chitosan-nanohydroxyapatite composite scaffolds for bone tissue engineering
    • Thein-Han WW, Misra RDK. Biomimetic chitosan-nanohydroxyapatite composite scaffolds for bone tissue engineering. Acta Biomater. 2009 ; 5: 1182-1197
    • (2009) Acta Biomater , vol.5 , pp. 1182-1197
    • Thein-Han, W.W.1    Misra, R.D.K.2
  • 42
    • 27444447463 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects
    • Geiger F, Bertram H, Berger I, et al. Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects. J Bone Miner Res. 2005 ; 20: 2028-2035
    • (2005) J Bone Miner Res , vol.20 , pp. 2028-2035
    • Geiger, F.1    Bertram, H.2    Berger, I.3
  • 43
    • 69849083362 scopus 로고    scopus 로고
    • Enhancement of bone formation by genetically-engineered bone marrow stromal cells expressing BMP-2, VEGF and angiopoietin-1
    • Hou H, Zhang X, Tang T, et al. Enhancement of bone formation by genetically-engineered bone marrow stromal cells expressing BMP-2, VEGF and angiopoietin-1. Biotechnol Lett. 2009 ; 31: 1183-1189
    • (2009) Biotechnol Lett , vol.31 , pp. 1183-1189
    • Hou, H.1    Zhang, X.2    Tang, T.3
  • 44
    • 75149145129 scopus 로고    scopus 로고
    • The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF165
    • Keeney M, van den Beucken JJJP, van der Kraan PM, et al. The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF165. Biomaterials. 2010 ; 31: 2893-2902
    • (2010) Biomaterials , vol.31 , pp. 2893-2902
    • Keeney, M.1    Van Den Beucken Jjjp2    Van Der Kraan, P.M.3
  • 45
    • 0034750066 scopus 로고    scopus 로고
    • Intracoronary administration of recombinant human vascular endothelial growth factor to patients with coronary artery disease
    • Henry TD, Rocha-Singh K, Isner JM, et al. Intracoronary administration of recombinant human vascular endothelial growth factor to patients with coronary artery disease. Am Heart J. 2001 ; 142: 872-880
    • (2001) Am Heart J , vol.142 , pp. 872-880
    • Henry, T.D.1    Rocha-Singh, K.2    Isner, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.