Muscle proteomics reveals novel insights into the pathophysiological mechanisms of collagen vi myopathies

Journal of Proteome Research

Volumn 13, Issue 11, 2014, Pages 5022-5030

  De Palma, Sara ^a,b   Capitanio, Daniele ^a,c   Vasso, Michele ^b   Braghetta, Paola ^d   Scotton, Chiara ^e   Bonaldo, Paolo ^d   Lochmüller, Hanns ^f   Muntoni, Francesco ^g   Ferlini, Alessandra ^e   Gelfi, Cecilia ^a,b,c  

^a UNIVERSITY OF MILAN   (Italy)

^b CNR   (Italy)

^c IRCCS POLICLINICO SAN DONATO   (Italy)

^d UNIVERSITY OF PADOVA   (Italy)

^e UNIVERSITY OF FERRARA   (Italy)

^f NEWCASTLE UNIVERSITY   (United Kingdom)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

2D DIGE; alpha ketoglutarate; Bethlem myopathy; Collagen VI; endoplasmic reticulum; hexosamine; Ullrich congenital muscular dystrophy; unfolded protein response

Indexed keywords

ACONITASE 2; ACONITATE HYDRATASE; ADENOSINE TRIPHOSPHATE SYNTHASE D SUBUNIT; ALPHA ACTIN; AMINO ACID; ASPARTATE AMINOTRANSFERASE ISOENZYME 1; BETA ENOLASE; CARBONATE DEHYDRATASE III; COLLAGEN TYPE 6; CREATINE KINASE MM; DESMIN; ENOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEXOSAMINE; KERATIN TYPE I; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; MALATE DEHYDROGENASE; MYOGLOBIN; MYOSIN LIGHT CHAIN 2; PHOSPHOGLYCERATE MUTASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; TRIOSEPHOSPHATE ISOMERASE; TROPONIN T; UNCLASSIFIED DRUG; UNINDEXED DRUG; FATTY ACID;

AEROBIC METABOLISM; ANAEROBIC METABOLISM; ARTICLE; AUTOPHAGY; BETHLEM MYOPATHY; CARBOHYDRATE SYNTHESIS; CITRIC ACID CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENERGY YIELD; FATTY ACID METABOLISM; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MECHANOTRANSDUCTION; MUSCLE BIOPSY; MUSCULAR DYSTROPHY; MYOPATHY; PHENOTYPE; PROTEIN GLYCOSYLATION; PROTEIN HOMEOSTASIS; PROTEIN MISFOLDING; PROTEIN QUALITY CONTROL SYSTEM; PROTEIN UNFOLDING; PROTEOMICS; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; ULLRICH CONGENITAL MUSCULAR DYSTROPHY; VASTUS LATERALIS MUSCLE; BIOPSY; CASE CONTROL STUDY; CONTRACTURE; MASS SPECTROMETRY; METABOLISM; MUSCULAR DYSTROPHIES; PATHOPHYSIOLOGY; PROCEDURES; REPRODUCIBILITY; SCLEROSIS; SKELETAL MUSCLE; UNFOLDED PROTEIN RESPONSE;

BIOPSY; CASE-CONTROL STUDIES; COLLAGEN TYPE VI; CONTRACTURE; ENDOPLASMIC RETICULUM STRESS; FATTY ACIDS; HEXOSAMINES; HUMANS; IMMUNOBLOTTING; MALE; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SCLEROSIS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TWO-DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; UNFOLDED PROTEIN RESPONSE;

EID: 84908868245     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr500675e     Document Type: Article

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