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Volumn 34, Issue 8, 2014, Pages 4457-4462

Clinical significance of urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) for metastatic sentinel lymph node involvement in breast cancer

Author keywords

Breast cancer; Plasminogen activator inhibitor type 1 (PAI 1); Sentinel lymph node biopsy; Urokinase type plasminogen activator (uPA)

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1; UROKINASE;

EID: 84908689754     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (36)
  • 3
    • 77954937112 scopus 로고    scopus 로고
    • Sentinel node identification rate and nodal involvement in the EORTC 10981-22023 AMAROS trial
    • Straver ME, Meijnen P, van Tienhoven G et al: Sentinel node identification rate and nodal involvement in the EORTC 10981-22023 AMAROS trial. Ann Surg Oncol 17: 1854-1861, 2010.
    • (2010) Ann Surg Oncol , vol.17 , pp. 1854-1861
    • Straver, M.E.1    Meijnen, P.2    Van Tienhoven, G.3
  • 4
    • 77957015140 scopus 로고    scopus 로고
    • Procedure guideline for sentinel lymph node diagnosis
    • Vogt H, Schmidt M, Bares R et al: Procedure guideline for sentinel lymph node diagnosis. Nuklearmedizin 2010 49: 167-172, 2010.
    • (2010) Nuklearmedizin , vol.49 , pp. 167-172
    • Vogt, H.1    Schmidt, M.2    Bares, R.3
  • 5
    • 1642375334 scopus 로고    scopus 로고
    • Urokinasetype plasminogen activator uPA and its inhibitor PAI-1: Novel tumour-derived factors with a high prognostic and predictive impact in breast cancer
    • Harbeck N, Kates RE, Gauger K et al: Urokinasetype plasminogen activator uPA and its inhibitor PAI-1: novel tumour-derived factors with a high prognostic and predictive impact in breast cancer. Thromb Haemost 91: 450-456, 2004.
    • (2004) Thromb Haemost , vol.91 , pp. 450-456
    • Harbeck, N.1    Kates, R.E.2    Gauger, K.3
  • 6
    • 0030788411 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator system in cancer metastasis: A review
    • Andreasen PA, Kjoller L, Christensen L et al: The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72: 1-22, 1997.
    • (1997) Int J Cancer , vol.72 , pp. 1-22
    • Andreasen, P.A.1    Kjoller, L.2    Christensen, L.3
  • 7
    • 12944328659 scopus 로고    scopus 로고
    • The plasminogen activation system as a novel target for therapeutic strategies
    • Schmitt M, Wilhelm O, Reuning U et al: The plasminogen activation system as a novel target for therapeutic strategies. Fibrinolysis 14: 114-132, 2000.
    • (2000) Fibrinolysis , vol.14 , pp. 114-132
    • Schmitt, M.1    Wilhelm, O.2    Reuning, U.3
  • 8
    • 0023735157 scopus 로고
    • Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report
    • Duffy MJ, O'Grady P, Devaney D et al: Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report. Cancer 62: 531-533,1988.
    • (1988) Cancer , vol.62 , pp. 531-533
    • Duffy, M.J.1    O'Grady, P.2    Devaney, D.3
  • 9
    • 0024428950 scopus 로고
    • Urokinase-type plasminogen activator antigen and early relapse in breast cancer
    • Jänicke F, Schmitt M, Ulm K et al: Urokinase-type plasminogen activator antigen and early relapse in breast cancer. Lancet 2: 1049, 1989.
    • (1989) Lancet , vol.2 , pp. 1049
    • Jänicke, F.1    Schmitt, M.2    Ulm, K.3
  • 10
    • 0025995880 scopus 로고
    • Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer
    • Jänicke F, Schmitt M and Graeff H: Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer. Semin Thromb Hemost 17: 303-312, 1991.
    • (1991) Semin Thromb Hemost , vol.17 , pp. 303-312
    • Jänicke, F.1    Schmitt, M.2    Graeff, H.3
  • 11
    • 2642705008 scopus 로고    scopus 로고
    • Prognostic impact of urokinase-type plasminogen activator (PA), PA inhibitor type-1 and tissue-type PA antigen levels in node-negative breast cancer: A prospective study on multicenter basis
    • Kim SJ, Shiba E, Kobayashi T et al: Prognostic impact of urokinase-type plasminogen activator (PA), PA inhibitor type-1 and tissue-type PA antigen levels in node-negative breast cancer: a prospective study on multicenter basis. Clin Cancer Res 19: 177-182, 1998.
    • (1998) Clin Cancer Res , vol.19 , pp. 177-182
    • Kim, S.J.1    Shiba, E.2    Kobayashi, T.3
  • 12
    • 0033968403 scopus 로고    scopus 로고
    • The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients
    • Foekens JA, Peters HA and Look MP et al: The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients. Cancer Res 60: 636-643, 2000.
    • (2000) Cancer Res , vol.60 , pp. 636-643
    • Foekens, J.A.1    Peters, H.A.2    Look, M.P.3
  • 13
    • 0042701433 scopus 로고    scopus 로고
    • Prognostic and predictive value of the urokinase-type plasminogen activator (uPA) and its inhibitors PAI-1 and PAI-2 in operable breast cancer
    • Cufer T, Borstnar S and Vrhovec I: Prognostic and predictive value of the urokinase-type plasminogen activator (uPA) and its inhibitors PAI-1 and PAI-2 in operable breast cancer. Int J Biol Markers 18: 106-115, 2003.
    • (2003) Int J Biol Markers , vol.18 , pp. 106-115
    • Cufer, T.1    Borstnar, S.2    Vrhovec, I.3
  • 14
    • 56249089339 scopus 로고    scopus 로고
    • Prospective Biomarker Trials Chemo N0 and NNBC-3 Europe Validate the Clinical Utility of Invasion Markers uPA and PAI-1 in Node-Negative Breast Cancer
    • Harbeck N, Schmitt M, Vetter M et al: Prospective Biomarker Trials Chemo N0 and NNBC-3 Europe Validate the Clinical Utility of Invasion Markers uPA and PAI-1 in Node-Negative Breast Cancer. Breast Care 3(suppl 2): 11-15, 2008.
    • (2008) Breast Care , vol.3 , pp. 11-15
    • Harbeck, N.1    Schmitt, M.2    Vetter, M.3
  • 15
    • 0037083657 scopus 로고    scopus 로고
    • Clinical relevance of invasion factors urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 for individualised therapy decisions in primary breast cancer is greatest when used in combination
    • Harbeck N, Kates RE and Schmitt M: Clinical relevance of invasion factors urokinase-type plasminogen activator and plasminogen activator inhibitor type 1 for individualised therapy decisions in primary breast cancer is greatest when used in combination. J Clin Oncol 20: 1000-1009, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 1000-1009
    • Harbeck, N.1    Kates, R.E.2    Schmitt, M.3
  • 16
    • 0034886716 scopus 로고    scopus 로고
    • Her2/neu and urokinase-type plasminogen activator and its inhibitor in breast cancer
    • Konecny G, Untch M, Arboleda J et al: Her2/neu and urokinase-type plasminogen activator and its inhibitor in breast cancer. Clin Cancer Res 7: 2448-2457, 2001.
    • (2001) Clin Cancer Res , vol.7 , pp. 2448-2457
    • Konecny, G.1    Untch, M.2    Arboleda, J.3
  • 17
    • 0141989949 scopus 로고    scopus 로고
    • Limited prognostic value of c-erbB-2 compared to uPA and PAI-1 in primary breast carcinoma
    • Bouchet C, Ferrero-Pous M, Hacene K et al: Limited prognostic value of c-erbB-2 compared to uPA and PAI-1 in primary breast carcinoma. Int J Biol Markers 18: 207-217, 2003.
    • (2003) Int J Biol Markers , vol.18 , pp. 207-217
    • Bouchet, C.1    Ferrero-Pous, M.2    Hacene, K.3
  • 18
    • 0037445194 scopus 로고    scopus 로고
    • Invasion factors uPA/ PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer
    • Zemzoum I, Kates RE, Ross JS et al: Invasion factors uPA/ PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer. J Clin Oncol 21: 1022-1028, 2003.
    • (2003) J Clin Oncol , vol.21 , pp. 1022-1028
    • Zemzoum, I.1    Kates, R.E.2    Ross, J.S.3
  • 19
    • 0037116616 scopus 로고    scopus 로고
    • Pooled analysis of prognostic impact of urokinasetype plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients
    • Look MP, van Putten WLK, Duffy MJ et al: Pooled analysis of prognostic impact of urokinasetype plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. J Natl Cancer Inst 94: 116-128, 2002.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 116-128
    • Look, M.P.1    Van Putten, W.L.K.2    Duffy, M.J.3
  • 20
    • 0037445194 scopus 로고    scopus 로고
    • Invasion factors uPA/PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer
    • Zemzoum I, Kates RE, Ross JS et al: Invasion factors uPA/PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer. J Clin Oncol 21(6): 1022-1028, 2003.
    • (2003) J Clin Oncol , vol.21 , Issue.6 , pp. 1022-1028
    • Zemzoum, I.1    Kates, R.E.2    Ross, J.S.3
  • 21
    • 0034802806 scopus 로고    scopus 로고
    • Prognostic Impact of Proteolytic Factors (Urokinase-Type Plasminogen Activator, Plasminogen Activator Inhibitor 1, and Cathepsins B, D, and L) in Primary Breast Cancer Reflects Effects of Adjuvant Systemic Therapy
    • Harbeck N, Alt U, Berger U et al: Prognostic Impact of Proteolytic Factors (Urokinase-Type Plasminogen Activator, Plasminogen Activator Inhibitor 1, and Cathepsins B, D, and L) in Primary Breast Cancer Reflects Effects of Adjuvant Systemic Therapy. Clin Cancer Res 7: 2757-2764, 2001.
    • (2001) Clin Cancer Res , vol.7 , pp. 2757-2764
    • Harbeck, N.1    Alt, U.2    Berger, U.3
  • 24
    • 0025273735 scopus 로고
    • Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1
    • Cubellis MV, Wun TC and Blasi F: Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. EMBO J 9: 1079-1085, 1990.
    • (1990) EMBO J , vol.9 , pp. 1079-1085
    • Cubellis, M.V.1    Wun, T.C.2    Blasi, F.3
  • 25
    • 0033014499 scopus 로고    scopus 로고
    • Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse
    • Harbeck N, Thomssen C, Berger U et al: Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse. Breast Cancer Research and Treatment 54: 147-157, 1999.
    • (1999) Breast Cancer Research and Treatment , vol.54 , pp. 147-157
    • Harbeck, N.1    Thomssen, C.2    Berger, U.3
  • 26
    • 84876691969 scopus 로고    scopus 로고
    • Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients
    • Harbeck N, Schmitt M, Meisner C et al: Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients. European Journal of Cancer 49: 1825-1835, 2003.
    • (2003) European Journal of Cancer , vol.49 , pp. 1825-1835
    • Harbeck, N.1    Schmitt, M.2    Meisner, C.3
  • 27
    • 7844236388 scopus 로고    scopus 로고
    • External quality assessment oftrans-European multicenter antigen determinations (enzyme-linked immuno sorbent assay) of urokinase-type plasminogen activator (uPA)and its type-1 inhibitor (PAI-1)in human breast cancer tissue extracts
    • Sweep CGJ, Geurts-Moe spot J and Grebenschikov N et al: External quality assessment oftrans-European multicenter antigen determinations (enzyme-linked immuno sorbent assay) of urokinase-type plasminogen activator (uPA)and its type-1 inhibitor (PAI-1)in human breast cancer tissue extracts. Br J Cancer 78: 1434-1441, 1998.
    • (1998) Br J Cancer , vol.78 , pp. 1434-1441
    • Sweep, C.G.J.1    Geurts-Moe Spot, J.2    Grebenschikov, N.3
  • 28
    • 67650834986 scopus 로고    scopus 로고
    • Feasibility of measuring the prognostic factors uPA and PAI-1 incore needle biopsy breast cancer specimens
    • Thomssen C, Harbeck N, Dittmer J et al: Feasibility of measuring the prognostic factors uPA and PAI-1 incore needle biopsy breast cancer specimens. J Natl Cancer Inst 101(14): 1028-1029, 2009.
    • (2009) J Natl Cancer Inst , vol.101 , Issue.14 , pp. 1028-1029
    • Thomssen, C.1    Harbeck, N.2    Dittmer, J.3
  • 29
    • 10244261646 scopus 로고    scopus 로고
    • A tumour marker utility grading system (TMUGS): A framework to evaluate clinical utility of tumour markers
    • Hayes DF, Bast R, Desch CE et al: A tumour marker utility grading system (TMUGS): a framework to evaluate clinical utility of tumour markers. J Natl Cancer Inst 88: 1456-1466, 1996.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1456-1466
    • Hayes, D.F.1    Bast, R.2    Desch, C.E.3
  • 30
    • 0031952403 scopus 로고    scopus 로고
    • Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer
    • Knoop A, Andreasen PA, Andersen JA et al: Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer. Br J Cancer 77: 932-940, 1998.
    • (1998) Br J Cancer , vol.77 , pp. 932-940
    • Knoop, A.1    Andreasen, P.A.2    Andersen, J.A.3
  • 31
    • 0036220929 scopus 로고    scopus 로고
    • Prognostic significance of plasminogen activator inhibitor-1 in breast cancer, with special emphasis on locoregional recurrence-free survival
    • Cufer T, Vrhovec I and Borstnar S: Prognostic significance of plasminogen activator inhibitor-1 in breast cancer, with special emphasis on locoregional recurrence-free survival. Int J Biol Markers 17: 33-41, 2002.
    • (2002) Int J Biol Markers , vol.17 , pp. 33-41
    • Cufer, T.1    Vrhovec, I.2    Borstnar, S.3
  • 32
    • 0033014499 scopus 로고    scopus 로고
    • Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse
    • Harbeck N, Thomssen C, Berger U et al: Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse. Breast Cancer Res Treat 54: 147-157, 1999.
    • (1999) Breast Cancer Res Treat , vol.54 , pp. 147-157
    • Harbeck, N.1    Thomssen, C.2    Berger, U.3
  • 33
    • 0036695216 scopus 로고    scopus 로고
    • Clinical Utility of Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor-1 Determination in Primary Breast Cancer Tissue for Individualized Therapy Concepts
    • Harbeck N, Schmitt M, Kates RE et al: Clinical Utility of Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor-1 Determination in Primary Breast Cancer Tissue for Individualized Therapy Concepts Clinical Breast Cancer 3(3): 196-200, 2002.
    • (2002) Clinical Breast Cancer , vol.3 , Issue.3 , pp. 196-200
    • Harbeck, N.1    Schmitt, M.2    Kates, R.E.3
  • 34
    • 0035918882 scopus 로고    scopus 로고
    • Randomized adjuvant therapy trial in high-risk lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type I
    • Jänicke F, Prechtl A, Thomssen C et al: Randomized adjuvant therapy trial in high-risk lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type I. J Natl Cancer Inst 93: 913-920, 2001.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 913-920
    • Jänicke, F.1    Prechtl, A.2    Thomssen, C.3
  • 35
    • 84899682350 scopus 로고    scopus 로고
    • Plasma plasminogen activator inhibitor-1 (PAI-1) levels in breast cancer - relationship with clinical outcome
    • Ferroni P, Roselli M, Portarena I et al: Plasma plasminogen activator inhibitor-1 (PAI-1) levels in breast cancer - relationship with clinical outcome. Anticancer Res 34(3): 1153-1161, 2014.
    • (2014) Anticancer Res , vol.34 , Issue.3 , pp. 1153-1161
    • Ferroni, P.1    Roselli, M.2    Portarena, I.3
  • 36
    • 84899704027 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in node-negative breast cancer: UPA/PAI-1 determinations for 163 cases
    • Vénat-Bouvet L, Fermeaux V, Leobon S et al: Adjuvant chemotherapy in node-negative breast cancer: UPA/PAI-1 determinations for 163 cases. Anticancer Res 34(3): 1213-1217, 2014.
    • (2014) Anticancer Res , vol.34 , Issue.3 , pp. 1213-1217
    • Vénat-Bouvet, L.1    Fermeaux, V.2    Leobon, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.