-
1
-
-
0030788411
-
The urokinase-type plasminogen activator system in cancer metastasis: A review
-
Andreasen PA, Kjöller L, Christensen L, et al. The urokinase-type plasminogen activator system in cancer metastasis: A review. Int J Cancer 1997; 72:1-22.
-
(1997)
Int. J. Cancer
, vol.72
, pp. 1-22
-
-
Andreasen, P.A.1
Kjöller, L.2
Christensen, L.3
-
2
-
-
12944328659
-
The plasminogen activation system as a novel target for therapeutic strategies
-
Schmitt M, Wilhelm OG, Reuning U, et al. The plasminogen activation system as a novel target for therapeutic strategies. Fibrinolysis 2000; 14:114-132.
-
(2000)
Fibrinolysis
, vol.14
, pp. 114-132
-
-
Schmitt, M.1
Wilhelm, O.G.2
Reuning, U.3
-
3
-
-
7844236388
-
External quality assessment of trans-European multicentre antigen determinations (ELISA) of urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) in human breast cancer tissue extracts
-
Sweep CGJ, Geurts-Moespot J, Grebenschikov N, et al. External quality assessment of trans-European multicentre antigen determinations (ELISA) of urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) in human breast cancer tissue extracts. Br J Cancer 1998; 78:1434-1441.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1434-1441
-
-
Sweep, C.G.J.1
Geurts-Moespot, J.2
Grebenschikov, N.3
-
4
-
-
84898699457
-
Some (quality control) considerations on development, validation and application of immuno(metric) tumour marker assays in clinical research. An EORTC-NCI working group report
-
In press
-
Sweep CGJ, Fritsche HA, Gion M, et al. Some (quality control) considerations on development, validation and application of immuno(metric) tumour marker assays in clinical research. An EORTC-NCI working group report. Int J Biol Markers 2002. In press.
-
(2002)
Int. J. Biol. Markers
-
-
Sweep, C.G.J.1
Fritsche, H.A.2
Gion, M.3
-
5
-
-
0023735157
-
Urokinase-plasminogen activator, a marker for aggressive breast cancers
-
Duffy MJ, O'Grady P, Devaney D, et al. Urokinase-plasminogen activator, a marker for aggressive breast cancers. Cancer 1988; 62:531-533.
-
(1988)
Cancer
, vol.62
, pp. 531-533
-
-
Duffy, M.J.1
O'Grady, P.2
Devaney, D.3
-
6
-
-
0032913404
-
ELISA for complexes of urokinase-type and tissue-type plasminogen activators with their type-1 inhibitor (uPA-PAI-1 and tPA-PAI-1)
-
Grebenschikov N, Sweep F, Geurts A, et al. ELISA for complexes of urokinase-type and tissue-type plasminogen activators with their type-1 inhibitor (uPA-PAI-1 and tPA-PAI-1). Int J Cancer 1999; 81:598-606.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 598-606
-
-
Grebenschikov, N.1
Sweep, F.2
Geurts, A.3
-
7
-
-
0030857717
-
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: Prognostic relevance and target for therapy
-
Schmitt M, Harbeck N, Thomssen C, et al. Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy. Thrombosis Haemostasis 1997; 78:285-296.
-
(1997)
Thrombosis Haemostasis
, vol.78
, pp. 285-296
-
-
Schmitt, M.1
Harbeck, N.2
Thomssen, C.3
-
8
-
-
0024428950
-
Urokinase-type plasminogen activator antigen and early relapse in breast cancer
-
Jänicke F, Schmitt M, Ulm K, et al. Urokinase-type plasminogen activator antigen and early relapse in breast cancer. Lancet 1989; 2:1049.
-
(1989)
Lancet
, vol.2
, pp. 1049
-
-
Jänicke, F.1
Schmitt, M.2
Ulm, K.3
-
9
-
-
0025127815
-
Urokinase-type plasminogen activator (uPA) antigen is a predictor of early relapse in breast cancer
-
Jänicke F, Schmitt M, Hafter R, et al. Urokinase-type plasminogen activator (uPA) antigen is a predictor of early relapse in breast cancer. Fibrinolysis 1990; 4:69-78.
-
(1990)
Fibrinolysis
, vol.4
, pp. 69-78
-
-
Jänicke, F.1
Schmitt, M.2
Hafter, R.3
-
10
-
-
0025995880
-
Clinical relevance of the urokinase-type and tissue type plasminogen activators and of their type 1 inhibitor in breast cancer
-
Jänicke F, Schmitt M, Graeff H. Clinical relevance of the urokinase-type and tissue type plasminogen activators and of their type 1 inhibitor in breast cancer. Sem Thromb Hemostasis 1991; 17:303-312.
-
(1991)
Sem. Thromb. Hemostasis
, vol.17
, pp. 303-312
-
-
Jänicke, F.1
Schmitt, M.2
Graeff, H.3
-
11
-
-
0027082979
-
Urokinase (uPA) and its inhibitor PAI-1 are strong, independent prognostic factors in node-negative breast cancer
-
Jänicke F, Schmitt M, Pache L, et al. Urokinase (uPA) and its inhibitor PAI-1 are strong, independent prognostic factors in node-negative breast cancer. Breast Cancer Res Treat 1993; 24:195-208.
-
(1993)
Breast Cancer Res. Treat
, vol.24
, pp. 195-208
-
-
Jänicke, F.1
Schmitt, M.2
Pache, L.3
-
12
-
-
0027223048
-
High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis
-
Grøondahl-Hansen J, Christensen IJ, Rosenquist C, et al. High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis. Cancer Res 1993; 53:2513-2521.
-
(1993)
Cancer Res
, vol.53
, pp. 2513-2521
-
-
Grøondahl-Hansen, J.1
Christensen, I.J.2
Rosenquist, C.3
-
13
-
-
0028048915
-
Plasminogen activator inhibitor-1 and prognosis in primary breast cancer
-
Foekens JA, Schmitt M, van Putten WLJ, et al: Plasminogen activator inhibitor-1 and prognosis in primary breast cancer. J Clin Oncol 1994; 12:1648-1658.
-
(1994)
J. Clin. Oncol
, vol.12
, pp. 1648-1658
-
-
Foekens, J.A.1
Schmitt, M.2
van Putten, W.L.J.3
-
14
-
-
0029950191
-
Urokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay
-
Fernö M, Bendahl PO, Borg Å, et al. Urokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay. Eur J Cancer 1996; 32a:793-801.
-
(1996)
Eur. J. Cancer
, vol.32 a
, pp. 793-801
-
-
Fernö, M.1
Bendahl, P.O.2
Borg, A.3
-
15
-
-
0344109584
-
Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients
-
Eppenberger U, Kueng W, Schlaeppi JM, et al. Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients. J Clin Oncol 1998; 16:3129-3136.
-
(1998)
J. Clin. Oncol
, vol.16
, pp. 3129-3136
-
-
Eppenberger, U.1
Kueng, W.2
Schlaeppi, J.M.3
-
16
-
-
2642705008
-
Prognostic impact of urokinase-type plasminogen activator (PA), PA inhibitor type-1 and tissue-type PA antigen levels in node-negative breast cancer: A prospective study on multi-center basis
-
Kim SJ, Siba E, Kobayashi T, et al. Prognostic impact of urokinase-type plasminogen activator (PA), PA inhibitor type-1 and tissue-type PA antigen levels in node-negative breast cancer: a prospective study on multi-center basis. Clin Cancer Res 1998; 4:177-182.
-
(1998)
Clin. Cancer Res
, vol.4
, pp. 177-182
-
-
Kim, S.J.1
Siba, E.2
Kobayashi, T.3
-
17
-
-
0031974329
-
Low cathepsin D and low plasminogen activator type 1 inhibitor in tumor cytosols defines a group of node negative breast cancer patients with low risk of recurrence
-
Kute TE, Grøondahl-Hansen J, Shao SM, et al. Low cathepsin D and low plasminogen activator type 1 inhibitor in tumor cytosols defines a group of node negative breast cancer patients with low risk of recurrence. Breast Cancer Res Treat 1998; 47:9-16.
-
(1998)
Breast Cancer Res. Treat
, vol.47
, pp. 9-16
-
-
Kute, T.E.1
Grøondahl-Hansen, J.2
Shao, S.M.3
-
18
-
-
0031952403
-
Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer
-
Knoop A, Andreasen PA, Andersen JA, et al. Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer. Br J Cancer 1998; 77:932-940.
-
(1998)
Br. J. Cancer
, vol.77
, pp. 932-940
-
-
Knoop, A.1
Andreasen, P.A.2
Andersen, J.A.3
-
19
-
-
0344549142
-
Dissemination index based on plasminogen activator system components in primary breast cancer
-
Bouchet C, Hacène K, Martin JP, et al. Dissemination index based on plasminogen activator system components in primary breast cancer. J Clin Oncol 1999; 17:3048-3057.
-
(1999)
J. Clin. Oncol
, vol.17
, pp. 3048-3057
-
-
Bouchet, C.1
Hacène, K.2
Martin, J.P.3
-
20
-
-
0033968403
-
Urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients
-
Foekens JA, Peters HA, Look MP, et al. Urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients. Cancer Res 2000; 60:636-643.
-
(2000)
Cancer Res
, vol.60
, pp. 636-643
-
-
Foekens, J.A.1
Peters, H.A.2
Look, M.P.3
-
21
-
-
0035918882
-
Randomized adjuvant therapy trial in high-risk lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type I
-
Jänicke F, Prechtl A, Thomssen C, et al. Randomized adjuvant therapy trial in high-risk lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type I. J Natl Cancer Inst 2001; 93:913-920.
-
(2001)
J. Natl. Cancer Inst
, vol.93
, pp. 913-920
-
-
Jänicke, F.1
Prechtl, A.2
Thomssen, C.3
-
22
-
-
0034886716
-
HER-2/neu and urokinase-type plasminogen activator and its inhibitor in breast cancer
-
Konecny G, Untch M, Arboleda J, et al. HER-2/neu and urokinase-type plasminogen activator and its inhibitor in breast cancer. Clin Cancer Res 2001; 7:2448-2457.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 2448-2457
-
-
Konecny, G.1
Untch, M.2
Arboleda, J.3
-
23
-
-
0037083657
-
Clinical relevance of invasion factors uPA and PAI-1 for individualized therapy decisions in primary breast cancer is greatest when used in combination
-
Harbeck N, Kates R, Schmitt M. Clinical relevance of invasion factors uPA and PAI-1 for individualized therapy decisions in primary breast cancer is greatest when used in combination. J Clin Oncol 2002; 20:1000-1009.
-
(2002)
J. Clin. Oncol
, vol.20
, pp. 1000-1009
-
-
Harbeck, N.1
Kates, R.2
Schmitt, M.3
-
24
-
-
0037116616
-
Pooled analysis of prognostic impact of uPA and PAI-1 in 8377 breast cancer patients
-
Look MP, van Putten WLJ, Duffy MJ, et al. Pooled analysis of prognostic impact of uPA and PAI-1 in 8377 breast cancer patients. J Natl Cancer Inst 2002; 94:116-128.
-
(2002)
J. Natl. Cancer Inst
, vol.94
, pp. 116-128
-
-
Look, M.P.1
van Putten, W.L.J.2
Duffy, M.J.3
-
25
-
-
0036220929
-
Prognostic significance of plasminogen activator inhibitor-1 in breast cancer, with special emphasis on locoregional recurrence-free survival
-
Cufer T, Vrhovec I, Borstnar S. Prognostic significance of plasminogen activator inhibitor-1 in breast cancer, with special emphasis on locoregional recurrence-free survival. Int J Biol Markers 2002; 17:33-41.
-
(2002)
Int. J. Biol. Markers
, vol.17
, pp. 33-41
-
-
Cufer, T.1
Vrhovec, I.2
Borstnar, S.3
-
26
-
-
0033014499
-
Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse
-
Harbeck N, Thomssen C, Berger U, et al. Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse. Breast Cancer Res Treat 1999; 54:147-157.
-
(1999)
Breast Cancer Res. Treat
, vol.54
, pp. 147-157
-
-
Harbeck, N.1
Thomssen, C.2
Berger, U.3
-
27
-
-
0032944657
-
Risk-group discrimination in node-negative breast cancer using invasion and proliferation markers. six-year median follow-up
-
Harbeck N, Dettmar P, Thomssen C, et al. Risk-group discrimination in node-negative breast cancer using invasion and proliferation markers. six-year median follow-up. Br J Cancer 1999; 80:419-426.
-
(1999)
Br. J. Cancer
, vol.80
, pp. 419-426
-
-
Harbeck, N.1
Dettmar, P.2
Thomssen, C.3
-
28
-
-
0034802806
-
Prognostic impact of proteolytic factors (uPA, PAI-1, cathepsins B, D, L) in primary breast cancer reflects effects of adjuvant systemic therapy
-
Harbeck N, Alt U, Krüger A, et al. Prognostic impact of proteolytic factors (uPA, PAI-1, cathepsins B, D, L) in primary breast cancer reflects effects of adjuvant systemic therapy. Clin Cancer Res 2001; 7:2757-2764.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 2757-2764
-
-
Harbeck, N.1
Alt, U.2
Krüger, A.3
-
29
-
-
0033109529
-
HER-2/neu gene amplification determined by in-situ hybridization (FISH) allows risk group assessment in node-negative breast cancer
-
Harbeck N, Ross J, Yurdseven S, et al. HER-2/neu gene amplification determined by in-situ hybridization (FISH) allows risk group assessment in node-negative breast cancer. Int J Oncol 1999; 14:663-671.
-
(1999)
Int. J. Oncol
, vol.14
, pp. 663-671
-
-
Harbeck, N.1
Ross, J.2
Yurdseven, S.3
-
31
-
-
84898702179
-
Enhanced benefit from adjuvant systemic chemotherapy in breast cancer patients classified high-risk according to uPA and PAI-1 (n = 3424)
-
In press
-
Harbeck N, Kates RE, Look MP, et al. Enhanced benefit from adjuvant systemic chemotherapy in breast cancer patients classified high-risk according to uPA and PAI-1 (n = 3424). Cancer Res 2002. In press.
-
(2002)
Cancer Res
-
-
Harbeck, N.1
Kates, R.E.2
Look, M.P.3
-
32
-
-
0035408087
-
Interference with the urokinase plasminogen activator system: A promising therapy concept for solid tumors
-
Muehlenweg B, Sperl S, Magdolen V, et al. Interference with the urokinase plasminogen activator system: a promising therapy concept for solid tumors. Exp Opin Biol Ther 2001; 1:683-691.
-
(2001)
Exp. Opin. Biol. Ther
, vol.1
, pp. 683-691
-
-
Muehlenweg, B.1
Sperl, S.2
Magdolen, V.3
-
33
-
-
0002961213
-
Urokinase (uPA) and PAI-1 as selection criteria for adjuvant chemotherapy in axillary node-negative breast cancer patients
-
Schmitt M, Graeff H, Janicke F, eds Netherlands: Elsevier Science
-
Jänicke F, Thomssen C, Pache L, et al. Urokinase (uPA) and PAI-1 as selection criteria for adjuvant chemotherapy in axillary node-negative breast cancer patients. In: Schmitt M, Graeff H, Janicke F, eds. Prospects in Diagnosis and Treatment of Cancer. Netherlands: Elsevier Science; 1994:207-218.
-
(1994)
Prospects in Diagnosis and Treatment of Cancer
, pp. 207-218
-
-
Jänicke, F.1
Thomssen, C.2
Pache, L.3
-
34
-
-
0029021196
-
Urokinase-type plasminogen activator and its inhibitor PAI-1: Predictors of poor response to tamoxifen therapy in recurrent breast cancer
-
Foekens JA, Look MP, Peters HA, et al. Urokinase-type plasminogen activator and its inhibitor PAI-1: predictors of poor response to tamoxifen therapy in recurrent breast cancer. J Natl Cancer Inst 1995; 87:751-756.
-
(1995)
J. Natl. Cancer Inst
, vol.87
, pp. 751-756
-
-
Foekens, J.A.1
Look, M.P.2
Peters, H.A.3
-
35
-
-
10244261646
-
Tumor marker utility grading system: A framework to evaluate clinical utility of tumor markers
-
Hayes DF, Bast RC, Desch CE, et al. Tumor marker utility grading system: a framework to evaluate clinical utility of tumor markers. J Natl Cancer Inst 1996; 88:1456-1466.
-
(1996)
J. Natl. Cancer Inst
, vol.88
, pp. 1456-1466
-
-
Hayes, D.F.1
Bast, R.C.2
Desch, C.E.3
-
36
-
-
0035806484
-
-
National Institutes of Health Consensus Development Conference statement: Adjuvant therapy for breast cancer November 1-3 2000
-
National Institutes of Health Consensus Development Conference statement: adjuvant therapy for breast cancer November 1-3, 2000. J Natl Cancer Inst 2001; 93:979-989.
-
(2001)
J. Natl. Cancer Inst
, vol.93
, pp. 979-989
-
-
-
37
-
-
0035884636
-
Meeting highlights: International Consensus Panel on the treatment of primary breast cancer
-
Goldhirsch A, Glick JH, Gelber RD, et al. Meeting highlights: International Consensus Panel on the treatment of primary breast cancer. J Clin Oncol 2001; 19:3817-3827.
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 3817-3827
-
-
Goldhirsch, A.1
Glick, J.H.2
Gelber, R.D.3
-
38
-
-
0026417610
-
Breast cancer prognostic factors: Evaluation guidelines
-
McGuire W. Breast cancer prognostic factors: evaluation guidelines. J Natl Cancer Inst 1991; 83:154-155.
-
(1991)
J. Natl. Cancer Inst
, vol.83
, pp. 154-155
-
-
McGuire, W.1
-
39
-
-
0034001315
-
Do we need better prognostic factors in node-negative breast cancer? Arbiter
-
Hayes D. Do we need better prognostic factors in node-negative breast cancer? Arbiter. Eur J Cancer 2000; 36:302-306.
-
(2000)
Eur. J. Cancer
, vol.36
, pp. 302-306
-
-
Hayes, D.1
-
40
-
-
0028885643
-
Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: A reference to early systemic disease in solid cancer
-
Heiss MM, Allgayer H, Gruetzner KU, et al. Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: A reference to early systemic disease in solid cancer. Nature Med 1995; 1:1035-1039.
-
(1995)
Nature Med
, vol.1
, pp. 1035-1039
-
-
Heiss, M.M.1
Allgayer, H.2
Gruetzner, K.U.3
-
41
-
-
84898691287
-
Wilex starts phase I trial with anti-metastatic urokinase inhibitor drug
-
[press release]. 2001; Available at Accessed August 7
-
Wilex starts phase I trial with anti-metastatic urokinase inhibitor drug [press release]. 2001; Available at: http://www.wilex.de/frames/News/press.htm. Accessed August 7, 2002.
-
(2002)
-
-
|