Risk factors for age at onset of dementia due to Alzheimer's disease in a sample of patients with low mean schooling from São Paulo, Brazil

International Journal of Geriatric Psychiatry

Volumn 29, Issue 10, 2014, Pages 1033-1039

  De Oliveira, Fabricio Ferreira ^a   Bertolucci, Paulo Henrique Ferreira ^a   Chen, Elizabeth Suchi ^a   Smith, Marilia Cardoso ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Alzheimer's disease; Cerebrovascular disorders; Dementia; Educational status; Neurodegenerative diseases; Risk factors

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E4;

AGED; ALZHEIMER DISEASE; ARTICLE; BODY MASS; BRAZIL; CARDIOVASCULAR DISEASE; COGNITION; DEGENERATIVE DISEASE; DEPRESSION; EDUCATIONAL STATUS; FAMILY HISTORY; FEMALE; HAPLOTYPE; HEAD INJURY; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PACEMAKER; PHYSICAL ACTIVITY; PHYSICAL INACTIVITY; RISK FACTOR; SANITATION; SMOKING; WAIST CIRCUMFERENCE; DEMENTIA; GENETICS; MIDDLE AGED; REGRESSION ANALYSIS; SOCIOECONOMICS; VERY ELDERLY;

AGE OF ONSET; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; BRAZIL; DEMENTIA; EDUCATIONAL STATUS; FEMALE; HUMANS; MALE; MIDDLE AGED; REGRESSION ANALYSIS; RISK FACTORS; SOCIOECONOMIC FACTORS;

EID: 84908666966     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.4094     Document Type: Article

References (27)

1. Albert M, Massaro J, DeCarli C, et al. 2010. Profiles by sex of brain MRI and cognitive function in the Framingham offspring study. Alzheimer Dis Assoc Disord 24: 190-193.
2. American Diabetes Association. 2006. Diagnosis and classification of diabetes mellitus. Diabetes Care 29(S1): S43-S48.
3. Barnes LL,Wilson RS, Schneider JA, et al. 2003. Gender, cognitive decline, and risk of ADin older persons. Neurology 60: 1777-1781.
4. Beeri MS, Rapp M, Silverman JM, et al. 2006. Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. Neurology 66: 1399-1404.
5. Bettens K, Sleegers K, Van Broeckhoven C. 2013. Genetic insights in Alzheimer's disease. Lancet Neurol 12: 92-104.
6. Chobanian AV, Bakris GL, Black HR, et al. 2003. The seventh report of the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure-The JNC 7 report. JAMA 289: 2560-2572.
7. Crane PK, Walker R, Hubbard RA, et al. 2013. Glucose levels and risk of dementia. N Engl J Med 369: 540-548.
8. De Oliveira FF, Bertolucci PHF, Chen ES, Smith MAC. 2014. Pharmacological modulation of cognitive and behavioral symptoms in patients with dementia due to Alzheimer's disease. J Neurol Sci 336: 103-108.
9. Feldstein CA. 2010. Effects of blood pressure changes on Alzheimer's disease. Neuroepidemiology 35: 202-212.
10. Ferrari C, Xu W-L, Wang H-X, et al. 2013. How can elderly apolipoprotein E e4 carriers remain free from dementia? Neurobiol Aging 34: 13-21.
11. Garibotto V, Borroni B, Sorbi S, et al. 2012. Education and occupation provide reserve in both ApoE e4 carrier and noncarrier patients with probable Alzheimer's disease. Neurol Sci 33: 1037-1042.
12. Harwood DG, Kalechstein A, Barker WW, et al. 2010. The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease. Int J Geriatr Psychiatry 25: 511-518.
13. Iraola-Guzmán S, Estivill X, Rabionet R. 2011. DNA methylation in neurodegenerative disorders: A missing link between genome and environment? Clin Genet 80: 1-14.
14. Kume K, Hanyu H, Sato T, et al. 2011. Vascular risk factors are associated with faster decline of Alzheimer disease: A longitudinal SPECT study. J Neurol 258: 1295-1303.
15. Leszek J, Sochocka M, Gasiorowski K. 2012. Vascular factors and epigenetic modifications in the pathogenesis of Alzheimer's disease. J Neurol Sci 323: 25-32.
16. Loeb C, Gandolfo C. 1983. Diagnostic evaluation of degenerative and vascular dementia. Stroke 14: 399-401.
17. Luchsinger JA, Reitz C, Honig LS, et al. 2005. Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology 65: 545-551.
18. Luchsinger JA, Honig LS, Tang MX, Devanand DP. 2008. Depressive symptoms, vascular risk factors, and Alzheimer's disease. Int J Geriatr Psychiatry 23: 922-928.
19. McKhann GM, Knopman DS, Chertkow H, et al. 2011. The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup. Alzheimers Dement 7: 263-269.
20. Middleton LE, Yaffe K. 2009. Promising strategies for the prevention of dementia. Arch Neurol 66: 1210-1215.
21. Musicco M, Palmer K, Salamone G, et al. 2009. Predictors of progression of cognitive decline in Alzheimer's disease: The role of vascular and sociodemographic factors. J Neurol 256: 1288-1295.
22. National Cholesterol Education Program. 2002. Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel iii) final report. Circulation 106: 3143-3421.
23. Purandare N, Burns A, Daly KJ, et al. 2006. Cerebral emboli as a potential cause of Alzheimer's disease and vascular dementia: Case-control study. BMJ 332: 1119-1124.
24. Steinberg M, Hess K, Corcoran C, et al. 2013. Vascular risk factors and neuropsychiatric symptoms in Alzheimer's disease: The cache county study. Int J Geriatr Psychiatry. DOI: 10.1002/gps.3980
25. Vemuri P, Lesnick TG, Przybelski SA, et al. 2012. Effect of lifestyle activities on Alzheimer disease biomarkers and cognition. Ann Neurol 72: 730-738.
26. Whitmer RA, Sidney S, Selby J, Claiborne Johnston S, Yaffe K. 2005. Midlife cardiovascular risk factors and risk of dementia in late life. Neurology 64: 277-281.
27. Zlokovic BV. 2011. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci 12: 723-738.