메뉴 건너뛰기




Volumn 20, Issue 10, 2014, Pages 930-934

A Postmortem Study to Compare Agonist and Antagonist 5-HT1A Receptor-binding Sites in Alzheimer's Disease

Author keywords

5 HT1A receptor; Alzheimer's disease; F1559; MPPF; PET; Serotonin

Indexed keywords

F15559 F 18; MPPF F 18; RADIOLIGAND; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; UNCLASSIFIED DRUG; 3-CHLORO-4-FLUOROPHENYL-(4-FLUORO-4-(((5-METHYLPYRIMIDIN-2-YLMETHYL)AMINO)METHYL)PIPERIDIN-1-YL)METHANONE; FLUORODEOXYGLUCOSE F 18; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; PROTEIN BINDING; PYRIMIDINE DERIVATIVE; SEROTONIN 1 AGONIST; SEROTONIN 1 ANTAGONIST; SEROTONIN 1A RECEPTOR;

EID: 84908662505     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12306     Document Type: Article
Times cited : (20)

References (29)
  • 1
    • 77956184841 scopus 로고    scopus 로고
    • Small-animal positron emission tomography as a tool for neuropharmacology
    • Lancelot S, Zimmer L. Small-animal positron emission tomography as a tool for neuropharmacology. Trends Pharmacol Sci 2010;9:411-417.
    • (2010) Trends Pharmacol Sci , vol.9 , pp. 411-417
    • Lancelot, S.1    Zimmer, L.2
  • 2
    • 84868149924 scopus 로고    scopus 로고
    • MPTP animal model of Parkinsonism: dopamine cell death or only tyrosine hydroxylase impairment? - A study using PET imaging, autoradiography and immunohistochemistry in the cat
    • Aznavour N, Cendres-Bozzi C, Lemoine L, et al. MPTP animal model of Parkinsonism: dopamine cell death or only tyrosine hydroxylase impairment? - A study using PET imaging, autoradiography and immunohistochemistry in the cat. CNS Neurosci Ther 2012;18:934-941.
    • (2012) CNS Neurosci Ther , vol.18 , pp. 934-941
    • Aznavour, N.1    Cendres-Bozzi, C.2    Lemoine, L.3
  • 3
    • 84860750674 scopus 로고    scopus 로고
    • PET radiotracers for molecular imaging in the brain: past, present and future
    • Zimmer L, Luxen A. PET radiotracers for molecular imaging in the brain: past, present and future. NeuroImage 2012;61:363-370.
    • (2012) NeuroImage , vol.61 , pp. 363-370
    • Zimmer, L.1    Luxen, A.2
  • 5
    • 34447322271 scopus 로고    scopus 로고
    • Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria
    • Dubois B, Feldman HH, Jacova C, et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 2007;6:734-746.
    • (2007) Lancet Neurol , vol.6 , pp. 734-746
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3
  • 6
    • 31444449245 scopus 로고    scopus 로고
    • Serotonin 1A receptors in the living brain of Alzheimer's disease patients
    • Kepe V, Barrio JR, Huang SC, et al. Serotonin 1A receptors in the living brain of Alzheimer's disease patients. Proc Nat Acad Sci USA 2006;103:702-707.
    • (2006) Proc Nat Acad Sci USA , vol.103 , pp. 702-707
    • Kepe, V.1    Barrio, J.R.2    Huang, S.C.3
  • 7
    • 38449084217 scopus 로고    scopus 로고
    • A positron emission tomography study of 5-hydroxytryptamine-1A receptors in Alzheimer disease
    • Lanctot KL, Hussey DF, Herrmann N, et al. A positron emission tomography study of 5-hydroxytryptamine-1A receptors in Alzheimer disease. Am J Geriatr Psychiatry 2007;15:888-898.
    • (2007) Am J Geriatr Psychiatry , vol.15 , pp. 888-898
    • Lanctot, K.L.1    Hussey, D.F.2    Herrmann, N.3
  • 8
    • 40849097282 scopus 로고    scopus 로고
    • A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease
    • Truchot L, Costes N, Zimmer L, et al. A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease. NeuroImage 2008;40:1251-1256.
    • (2008) NeuroImage , vol.40 , pp. 1251-1256
    • Truchot, L.1    Costes, N.2    Zimmer, L.3
  • 9
    • 34548413607 scopus 로고    scopus 로고
    • Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment
    • Truchot L, Costes SN, Zimmer L, et al. Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment. Neurology 2007;69:1012-1017.
    • (2007) Neurology , vol.69 , pp. 1012-1017
    • Truchot, L.1    Costes, S.N.2    Zimmer, L.3
  • 10
    • 33847067140 scopus 로고    scopus 로고
    • A preliminary open-label study of 5-HT1A partial agonist tandospirone for behavioural and psychological symptoms associated with dementia
    • Sato S, Mizukami K, Asada T. A preliminary open-label study of 5-HT1A partial agonist tandospirone for behavioural and psychological symptoms associated with dementia. Int J Neuropsychopharmacol 2007;10:281-283.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 281-283
    • Sato, S.1    Mizukami, K.2    Asada, T.3
  • 11
    • 0021892571 scopus 로고
    • [3H]8-hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-Hydroxytryptamine sites in various regions of the rat brain
    • Hall MD, El Mestikawy S, Emerit MB, Pichat L, Hamon M, Gozlan H. [3H]8-hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-Hydroxytryptamine sites in various regions of the rat brain. J Neurochem 1985;44:1685-1696.
    • (1985) J Neurochem , vol.44 , pp. 1685-1696
    • Hall, M.D.1    El Mestikawy, S.2    Emerit, M.B.3    Pichat, L.4    Hamon, M.5    Gozlan, H.6
  • 12
    • 0026662897 scopus 로고
    • Further evidence for differential affinity states of the serotonine 1A receptor in rat hippocampus
    • Mongeau R, Welner SA, Quirion R, Suranyi-Cadotte BE. Further evidence for differential affinity states of the serotonine 1A receptor in rat hippocampus. Brain Res 1992;590:229-238.
    • (1992) Brain Res , vol.590 , pp. 229-238
    • Mongeau, R.1    Welner, S.A.2    Quirion, R.3    Suranyi-Cadotte, B.E.4
  • 13
    • 0028273228 scopus 로고
    • Heterogeneity of cortical and hippocampal 5-HT1A receptors: reappraisal of homogenate binding with 8-[3H]hydroxydipropylaminotetralin
    • Nénonéné EK, Radja F, Carli M, Grondin L, Reader TA. Heterogeneity of cortical and hippocampal 5-HT1A receptors: reappraisal of homogenate binding with 8-[3H]hydroxydipropylaminotetralin. J Neurochem 1994;62:1822-1834.
    • (1994) J Neurochem , vol.62 , pp. 1822-1834
    • Nénonéné, E.K.1    Radja, F.2    Carli, M.3    Grondin, L.4    Reader, T.A.5
  • 14
    • 77954536179 scopus 로고    scopus 로고
    • 5-HT1A receptor-regulated signal transduction pathways in brain
    • Polter AM, Li X. 5-HT1A receptor-regulated signal transduction pathways in brain. Cell Signal 2010;22:1406-1412.
    • (2010) Cell Signal , vol.22 , pp. 1406-1412
    • Polter, A.M.1    Li, X.2
  • 15
    • 78751662442 scopus 로고    scopus 로고
    • The role of G protein-coupled receptors in the pathology of Alzheimer's disease
    • Thathiah A, De Strooper B. The role of G protein-coupled receptors in the pathology of Alzheimer's disease. Nat Rev Neurosci 2011;12:73-87.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 73-87
    • Thathiah, A.1    De Strooper, B.2
  • 16
    • 33645105867 scopus 로고    scopus 로고
    • A comparison of in vivo and in vitro neuroimaging of 5-HT 1A receptor binding sites in the cat brain
    • Aznavour N, Rbah L, Leger L, et al. A comparison of in vivo and in vitro neuroimaging of 5-HT 1A receptor binding sites in the cat brain. J Chem Neuroanat 2006;31:226-232.
    • (2006) J Chem Neuroanat , vol.31 , pp. 226-232
    • Aznavour, N.1    Rbah, L.2    Leger, L.3
  • 17
    • 47549094635 scopus 로고    scopus 로고
    • Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium
    • Alafuzoff I, Arzberger T, Al-Sarraj S, et al. Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium. Brain Pathol 2008;18:484-496.
    • (2008) Brain Pathol , vol.18 , pp. 484-496
    • Alafuzoff, I.1    Arzberger, T.2    Al-Sarraj, S.3
  • 18
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991;82:239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 19
    • 77949261526 scopus 로고    scopus 로고
    • [18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging
    • Lemoine L, Verdurand M, Vacher B, et al. [18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging. Eur J Nucl Med Mol Imaging 2010;37:594-605.
    • (2010) Eur J Nucl Med Mol Imaging , vol.37 , pp. 594-605
    • Lemoine, L.1    Verdurand, M.2    Vacher, B.3
  • 21
    • 67650222044 scopus 로고    scopus 로고
    • Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist
    • Newman-Tancredi A, Martel JC, Assié MB, et al. Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist. Br J Pharmacol 2009;156:338-353.
    • (2009) Br J Pharmacol , vol.156 , pp. 338-353
    • Newman-Tancredi, A.1    Martel, J.C.2    Assié, M.B.3
  • 23
    • 0030610492 scopus 로고    scopus 로고
    • [3H]WAY-100635 for 5-HT1A receptor autoradiography in human brain: a comparison with [3H]8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia
    • Burnet PWJ, Eastwood SL, Harrison PJ. [3H]WAY-100635 for 5-HT1A receptor autoradiography in human brain: a comparison with [3H]8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia. Neurochem Int 1997;30:565-574.
    • (1997) Neurochem Int , vol.30 , pp. 565-574
    • Burnet, P.W.J.1    Eastwood, S.L.2    Harrison, P.J.3
  • 24
    • 17044459906 scopus 로고    scopus 로고
    • Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635
    • Hall H, Lundkvist C, Halldin C, et al. Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635. Brain Res 1997;745:96-108.
    • (1997) Brain Res , vol.745 , pp. 96-108
    • Hall, H.1    Lundkvist, C.2    Halldin, C.3
  • 25
    • 33644877574 scopus 로고    scopus 로고
    • A 18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging
    • Costes N, Merlet I, Ostrowsky K, et al. A 18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging. J Nucl Med 2005;46:1980-1989.
    • (2005) J Nucl Med , vol.46 , pp. 1980-1989
    • Costes, N.1    Merlet, I.2    Ostrowsky, K.3
  • 26
    • 0035937482 scopus 로고    scopus 로고
    • Gender-specific aging effects on the serotonin 1A receptor
    • Cidis Meltzer C, Drevets WC, Price JC, et al. Gender-specific aging effects on the serotonin 1A receptor. Brain Res 2001;895:9-17.
    • (2001) Brain Res , vol.895 , pp. 9-17
    • Cidis Meltzer, C.1    Drevets, W.C.2    Price, J.C.3
  • 27
    • 0036469258 scopus 로고    scopus 로고
    • Loss of stimulatory effect of guanosine triphosphate on [(35)S]GTPgammaS binding correlates with Alzheimer's disease neurofibrillary pathology in entorhinal cortex and CA1 hippocampal subfield
    • Garcia-Jimenez A, Cowburn RF, Ohm TG, et al. Loss of stimulatory effect of guanosine triphosphate on [(35)S]GTPgammaS binding correlates with Alzheimer's disease neurofibrillary pathology in entorhinal cortex and CA1 hippocampal subfield. J Neurosci Res 2002;67:388-398.
    • (2002) J Neurosci Res , vol.67 , pp. 388-398
    • Garcia-Jimenez, A.1    Cowburn, R.F.2    Ohm, T.G.3
  • 28
    • 13344277367 scopus 로고    scopus 로고
    • Altered G-protein coupling of a frontal cortical low affinity [3H]8-hydroxy-N, N-dipropyl-2-aminotetralin serotonergic binding site in Alzheimer's disease
    • Weinstein D, Magnuson D, Lee J. Altered G-protein coupling of a frontal cortical low affinity [3H]8-hydroxy-N, N-dipropyl-2-aminotetralin serotonergic binding site in Alzheimer's disease. Behav Brain Res 1996;73:325-329.
    • (1996) Behav Brain Res , vol.73 , pp. 325-329
    • Weinstein, D.1    Magnuson, D.2    Lee, J.3
  • 29
    • 67650021262 scopus 로고    scopus 로고
    • Increased binding to 5-HT1A and 5-HT2A receptors is associated with large vessel infarction and relative preservation of cognition
    • Elliott MS, Ballard CG, Kalaria RN, Perry R, Hortobagyi T, Francis PT. Increased binding to 5-HT1A and 5-HT2A receptors is associated with large vessel infarction and relative preservation of cognition. Brain 2009;132:1858-1865.
    • (2009) Brain , vol.132 , pp. 1858-1865
    • Elliott, M.S.1    Ballard, C.G.2    Kalaria, R.N.3    Perry, R.4    Hortobagyi, T.5    Francis, P.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.