Modelling Alzheimer-like cognitive deficits in rats using biperiden as putative cognition impairer

Behavioural Brain Research

Volumn 274, Issue , 2014, Pages 307-311

  Szczodry, Olga ^a   van der Staay, Franz Josef ^b   Arndt, Saskia S ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Animal model; Biperiden; Cone field; Learning; Reference memory; Working memory

Indexed keywords

BIPERIDEN; SCOPOLAMINE; MUSCARINIC RECEPTOR BLOCKING AGENT;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE MODEL; LEARNING; MALE; NONHUMAN; RAT; REFERENCE MEMORY; REWARD; SENSORIMOTOR FUNCTION; TASK PERFORMANCE; WORKING MEMORY; ANIMAL; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; MAZE TEST; REACTION TIME; SHORT TERM MEMORY;

ANIMALS; BIPERIDEN; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MAZE LEARNING; MEMORY, SHORT-TERM; MUSCARINIC ANTAGONISTS; RATS; REACTION TIME; REWARD;

EID: 84908641341     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.08.036     Document Type: Article

References (24)

1. Bouger P.C.M., van der Staay F.J. Rats with scopolamine- or MK-801-induced spatial discrimination deficits in the cone field task: animal models for impaired spatial orientation performance. Eur Neuropsychopharmacol 2005, 15:331-346.
2. Klinkenberg I., Blokland A. The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies. Neurosci Biobehav Rev 2010, 34:1307-1350.
3. World Health Organization Alzheimer Disease Organization Dementia: A Public Health Priority 2012, WHO Press.
4. Bartus R.T., Dean R.L., Beer B., Lippaa S. The cholinergic hypothesis of geriatric memory dysfunction. Science 1982, 217:408-414.
5. Van der Staay F.J., Bouger P.C. Effects of the cholinesterase inhibitors donepezil and metrifonate on scopolamine-induced impairments in the spatial cone field orientation task in rats. Behav Brain Res 2005, 156:1-10.
6. Prickaerts J., Honig W., Schmidt B., Blokland A. Metrifonate improves working but not reference memory performance in a spatial cone field task. Eur J Pharmacol 1999, 380:61-65.
7. Klinkenberg I., Blokland A. A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairment. Psychopharmacology (Berl) 2011, 215:549-566.
8. Wall P.M., Flinn J., Messier C. Infralimbic muscarinic M1 receptors modulate anxiety-like behaviour and spontaneous working memory in mice. Psychopharmacology (Berl) 2001, 155:58-68.
9. Leon J.De. Paying attention to pharmacokinetic and pharmacodynamic mechanisms to pro- gress in the area of anticholinergic use in geriatric patients. Curr Drug Metab 2011, 12(7):635-646.
10. Bolden C., Cusack B., Richelson E. Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells. J Pharmacol Exp Ther 1992, 260:576-580.
11. Caccamo A., Oddo S., Billings L.M., Green K.N., Martinez-Coria H., Fisher A., et al. M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron 2006, 49:671-682.
12. Van der Staay F.J., Gieling E.T., Pinzón N.E., Nordquist R.E., Ohl F. The appetitively motivated "cognitive" holeboard: a family of complex spatial discrimination tasks for assessing learning and memory. Neurosci Biobehav Rev 2012, 36:379-403.
13. Van der Staay F.J., Krechting B., Blokland A., Raaijmakers W. The cone field: a spatial discrimination task for the automatic and simultaneous assessment of working and reference memory in rats. J Neurosci Methods 1990, 31:13-22.
14. Van der Staay F., Raaijmakers W., Lammers A., Tonnaer J. Selective fimbria lesions impair acquisition of working and reference memory of rats in a complex spatial discrimination task. Behav Brain Res 1989, 32:151-161.
15. Grimaldi R., Perucca E., Ruberto G., Gelmi C., Trimarchi F., Hollmann M., et al. Pharmacokinetic and pharmacodynamic studies following the intravenous and oral administration of the antiparkinsonian drug biperiden to normal subjects. Eur J Clin Pharmacol 1986, 29:735-737.
16. Van der Staay F.J. Spatial working memory and reference memory of Brown Norway and WAG rats in a holeboard discrimination task. Neurobiol Learn Mem 1999, 71:113-125.
17. Van der Staay F.J., van Nies J., Raaijmakers W. The effects of aging in rats on working and reference memory performance in a spatial holeboard discrimination task. Behav Neural Biol 1990, 53:356-370.
18. Myhrer T., Enger S., Aas P. Antiparkinson drugs used as prophylactics for nerve agents: studies of cognitive side effects in rats. Pharmacol Biochem Behav 2008, 89:633-638.
19. Kimura Y., Ohue M., Kitaura T., Kihira K. Amnesic effects of the anticholinergic drugs, trihexyphenidyl and biperiden: differences in binding properties to the brain muscarinic receptor. Brain Res 1999, 834:6-12.
20. Roldán G., Bolaños-Badillo E., González-Sánchez H., Quirarte G.L., Prado-Alcalá R.A. Selective M1 muscarinic receptor antagonists disrupt memory consolidation of inhibitory avoidance in rats. Neurosci Lett 1997, 230:93-96.
21. Erhardt A., Müller M., Rödel A. Consequences of chronic social stress on behaviour and vasopressin gene expression in the PVN of DBA/2OlaHsd mice - influence of treatment with the CRHR1-antagonist R121919/NBI 30775. J Psychopharmacol 2009, 23:31-39.
22. Van Goethem N.P., Rutten K., van der Staay F.J., Jans L.A.W., Akkerman S., Steinbusch H.W.M., et al. Object recognition testing: rodent species, strains, housing conditions, and estrous cycle. Behav Brain Res 2012, 232:323-334.
23. Riedel G., Platt B., Micheau J. Glutamate receptor function in learning and memory. Behav Brain Res 2003, 140:1-47.
24. Deacon R.M.J., Rawlins J.N.P. T-maze alternation in the rodent. Nat Protoc 2006, 1:7-12.