Green tea extract and its major constituent, epigallocatechin-3-gallate, induce epithelial beta-defensin secretion and prevent beta-defensin degradation by Porphyromonas gingivalis

Journal of Periodontal Research

Volumn 49, Issue 5, 2014, Pages 615-623

  Lombardo Bedran, T B ^a   Feghali, K ^b   Zhao, L ^c   Palomari Spolidorio, D M ^a   Grenier, D ^b  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITÉ LAVAL   (Canada)

^c SICHUAN UNIVERSITY   (China)

Author keywords

Porphyromonas gingivalis; Beta defensin; Epigallocatechin gallate; Epithelial cells; Green tea; Periodontal disease

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA DEFENSIN; CATECHIN; DEFB1 PROTEIN, HUMAN; DEFB4A PROTEIN, HUMAN; ENZYME INHIBITOR; EPIGALLOCATECHIN GALLATE; IMIDAZOLE DERIVATIVE; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRILE; PLANT EXTRACT; PYRIDINE DERIVATIVE;

ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CAMELLIA SINENSIS; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; EPITHELIUM CELL; GINGIVA; HUMAN; METABOLISM; PORPHYROMONAS GINGIVALIS; PROTEIN DEGRADATION; SECRETION (PROCESS); SIGNAL TRANSDUCTION; UPREGULATION;

BETA-DEFENSINS; BUTADIENES; CAMELLIA SINENSIS; CATECHIN; CELL LINE; CELL SURVIVAL; ENZYME INHIBITORS; EPITHELIAL CELLS; GINGIVA; HUMANS; IMIDAZOLES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; PORPHYROMONAS GINGIVALIS; PROTEOLYSIS; PYRIDINES; UP-REGULATION;

EID: 84908604484     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/jre.12142     Document Type: Article

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