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Volumn 52, Issue 11, 2014, Pages 1052-1061

Differential toxicological endpoints of di(2-ethylhexyl) phthalate (DEHP) exposure in MCF-7 and MDA-MB-231 cell lines: Possible estrogen receptor α (ERα) independent modulations

Author keywords

Cell cycle; DEHP; Estrogen receptors ; Label free quantification; Secretome

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA, HUMAN; LACTOFERRIN; LTF PROTEIN, HUMAN; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; POLLUTANT; TAMOXIFEN; TUMOR PROTEIN;

EID: 84908564315     PISSN: 00195189     EISSN: 09751009     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (38)
  • 1
    • 84908597588 scopus 로고    scopus 로고
    • USFDA, Safety assessment of di (2-ethylhexyl) phthalate (DEHP) release from medical devices
    • Washington, DC
    • USFDA, Safety assessment of di (2-ethylhexyl) phthalate (DEHP) release from medical devices. US Food and drug administration. Washington, DC, 2002. http://www.fda.gov/cdrh/ost/dehp-pvc.pdf.
    • (2002) US Food and drug administration
  • 3
    • 79960872887 scopus 로고    scopus 로고
    • Modeling human exposure to phthalate esters: A comparison of indirect and biomonitoring estimation methods
    • Clark KE, David RM, Guinn R, Kramarz KW, Lampi MA & Staples CA, Modeling human exposure to phthalate esters: A comparison of indirect and biomonitoring estimation methods, Hum Ecol Risk Assess, 17 (2011) 923.
    • (2011) Hum Ecol Risk Assess , vol.17 , pp. 923
    • Clark, K.E.1    David, R.M.2    Guinn, R.3    Kramarz, K.W.4    Lampi, M.A.5    Staples, C.A.6
  • 4
    • 2142698524 scopus 로고    scopus 로고
    • Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro
    • Okubo T, Suzuki T, Yokoyama Y, Kano K & Kano I, Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro, Biol Pharm Bull, 26 (2003) 1219.
    • (2003) Biol Pharm Bull , vol.26 , pp. 1219
    • Okubo, T.1    Suzuki, T.2    Yokoyama, Y.3    Kano, K.4    Kano, I.5
  • 5
    • 8444237811 scopus 로고    scopus 로고
    • Phthalates inhibit tamoxifeninduced apoptosis in MCF-7 human breast cancer cells
    • Kim IY, Han SY & Moon A, Phthalates inhibit tamoxifeninduced apoptosis in MCF-7 human breast cancer cells, J Toxicol Environ Health A, 67 (2004) 2025.
    • (2004) J Toxicol Environ Health A , vol.67 , pp. 2025
    • Kim, I.Y.1    Han, S.Y.2    Moon, A.3
  • 7
    • 70350602531 scopus 로고    scopus 로고
    • Comparison of in vitro hormone activities of selected phthalates using reporter gene assays
    • Shen O, Du G, Sun H, Wu W, Jiang Y, Song L & Wang X, Comparison of in vitro hormone activities of selected phthalates using reporter gene assays, Toxicol Lett, 191 (2009) 9.
    • (2009) Toxicol Lett , vol.191 , pp. 9
    • Shen, O.1    Du, G.2    Sun, H.3    Wu, W.4    Jiang, Y.5    Song, L.6    Wang, X.7
  • 8
    • 84863017101 scopus 로고    scopus 로고
    • Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway
    • Hsieh TH, Tsai CF, Hsu CY, Kuo PL, Lee JN, Chai CY, Wang SC & Tsai EM, Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway, FASEB J, 26 (2012) 778.
    • (2012) FASEB J , vol.26 , pp. 778
    • Hsieh, T.H.1    Tsai, C.F.2    Hsu, C.Y.3    Kuo, P.L.4    Lee, J.N.5    Chai, C.Y.6    Wang, S.C.7    Tsai, E.M.8
  • 9
    • 27144543670 scopus 로고    scopus 로고
    • Investigations on cellular proliferation induced by zearalenone and its derivatives in relation to the estrogenic parameters
    • Minervini F, Giannoccaro A, Cavallini A & Angelo V, Investigations on cellular proliferation induced by zearalenone and its derivatives in relation to the estrogenic parameters, Toxicol Lett, 159 (2005) 272.
    • (2005) Toxicol Lett , vol.159 , pp. 272
    • Minervini, F.1    Giannoccaro, A.2    Cavallini, A.3    Angelo, V.4
  • 12
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • Furr BJA & Jordan VC, The pharmacology and clinical uses of tamoxifen, Pharmacol Ther, 25 (1984) 127.
    • (1984) Pharmacol Ther , vol.25 , pp. 127
    • Furr, B.J.A.1    Jordan, V.C.2
  • 13
    • 0033253548 scopus 로고    scopus 로고
    • The breast cancer prevention trial: Should women at high risk take tamoxifen?
    • McKeon VA, The breast cancer prevention trial: Should women at high risk take tamoxifen? J Obstet Gynecol Neonatal Nurs, 28 (1999) 34.
    • (1999) J Obstet Gynecol Neonatal Nurs , vol.28 , pp. 34
    • McKeon, V.A.1
  • 14
    • 0034606697 scopus 로고    scopus 로고
    • Estimation of tamoxifens’s efficiency for preventing the formation and growth of breast tumors
    • Radmacher MD & Simon R, Estimation of tamoxifens’s efficiency for preventing the formation and growth of breast tumors, J Natl Cancer Inst, 92 (2000) 48.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 48
    • Radmacher, M.D.1    Simon, R.2
  • 15
    • 0029792201 scopus 로고    scopus 로고
    • Cell-cycle arrest, micronucleus formation, and cell death in growth inhibition of MCF-7 breast cancer cells by tamoxifen and cisplatin
    • Otto A, Paddenberg R, Schubert S & Mannhertz H, Cell-cycle arrest, micronucleus formation, and cell death in growth inhibition of MCF-7 breast cancer cells by tamoxifen and cisplatin, J Cancer Res Clin Oncol, 22 (1996) 603.
    • (1996) J Cancer Res Clin Oncol , vol.22 , pp. 603
    • Otto, A.1    Paddenberg, R.2    Schubert, S.3    Mannhertz, H.4
  • 17
    • 0029157380 scopus 로고
    • Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells
    • Teixeira C, Reed JC & Pratt MA, Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells, Cancer Res, 55 (1995) 3902.
    • (1995) Cancer Res , vol.55 , pp. 3902
    • Teixeira, C.1    Reed, J.C.2    Pratt, M.A.3
  • 18
    • 13844312665 scopus 로고    scopus 로고
    • Differential proteomics: An overview of gel and non-gel based approaches
    • Monteoliva L & Albar JP, Differential proteomics: an overview of gel and non-gel based approaches, Brief Funct Genomic Proteomic, 3 (2004) 220.
    • (2004) Brief Funct Genomic Proteomic , vol.3 , pp. 220
    • Monteoliva, L.1    Albar, J.P.2
  • 20
    • 84872684824 scopus 로고    scopus 로고
    • Proteomic analysis of endothelial cell secretome: A mean of studying the pleiotropic effects of Hmg-CoA reductase inhibitors
    • Brioschi M, Lento S, Tremoli E & Banfi C, Proteomic analysis of endothelial cell secretome: A mean of studying the pleiotropic effects of Hmg-CoA reductase inhibitors, J Proteomics, 78 (2013) 346.
    • (2013) J Proteomics , vol.78 , pp. 346
    • Brioschi, M.1    Lento, S.2    Tremoli, E.3    Banfi, C.4
  • 21
    • 73649116726 scopus 로고    scopus 로고
    • Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach
    • Xue H, Lu B, Zhang J, Wu M, Huang Q, Wu Q, Sheng H, Wu D, Hu J & Lai M, Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach, J Proteome Res, 9 (2010) 545.
    • (2010) J Proteome Res , vol.9 , pp. 545
    • Xue, H.1    Lu, B.2    Zhang, J.3    Wu, M.4    Huang, Q.5    Wu, Q.6    Sheng, H.7    Wu, D.8    Hu, J.9    Lai, M.10
  • 22
    • 0034728669 scopus 로고    scopus 로고
    • Improving the reproducibility of the MCF-7 cell proliferation assay for the detection of xenoestrogens
    • Payne J, Jones C, Lakhani S & Kortenkamp A, Improving the reproducibility of the MCF-7 cell proliferation assay for the detection of xenoestrogens, Sci Total Environ, 248 (2000) 51.
    • (2000) Sci Total Environ , vol.248 , pp. 51
    • Payne, J.1    Jones, C.2    Lakhani, S.3    Kortenkamp, A.4
  • 23
    • 33846330891 scopus 로고    scopus 로고
    • Di-(2-ethylhexyl) phthalate suppresses tamoxifen-induced apoptosis in GH3 pituitary cells
    • Kim HS, Ishizaka M, Kazusaka A & Fujita F, Di-(2-ethylhexyl) phthalate suppresses tamoxifen-induced apoptosis in GH3 pituitary cells, Arch Toxicol, 81 (2007) 27.
    • (2007) Arch Toxicol , vol.81 , pp. 27
    • Kim, H.S.1    Ishizaka, M.2    Kazusaka, A.3    Fujita, F.4
  • 24
    • 34250805606 scopus 로고    scopus 로고
    • Tamoxifen-induced rapid death of MCF-7 breast cancer cells is mediated via extracellularly signal-regulated kinase signaling and can be abrogated by estrogen
    • Zheng A, Kallio A & Harkonen P, Tamoxifen-induced rapid death of MCF-7 breast cancer cells is mediated via extracellularly signal-regulated kinase signaling and can be abrogated by estrogen, Endocrinology, 148 (2007) 2764.
    • (2007) Endocrinology , vol.148 , pp. 2764
    • Zheng, A.1    Kallio, A.2    Harkonen, P.3
  • 25
    • 0016738010 scopus 로고
    • Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining
    • Krishan A, Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining, J Cell Biol, 66 (1975) 188.
    • (1975) J Cell Biol , vol.66 , pp. 188
    • Krishan, A.1
  • 27
    • 63049138916 scopus 로고    scopus 로고
    • Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures
    • Li GZ, Vissers JP, Silva JC, Golick D, Gorenstein MV & Geromanos SJ, Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures, Proteomics, 9 (2009) 1696.
    • (2009) Proteomics , vol.9 , pp. 1696
    • Li, G.Z.1    Vissers, J.P.2    Silva, J.C.3    Golick, D.4    Gorenstein, M.V.5    Geromanos, S.J.6
  • 28
    • 0036910768 scopus 로고    scopus 로고
    • Estrogen regulation of transferrin gene expression in MCF-7 human breast cancer cells
    • Vyhlidal C, Li X & Safe S, Estrogen regulation of transferrin gene expression in MCF-7 human breast cancer cells, J Mol Endocrinol, 29 (2002) 305.
    • (2002) J Mol Endocrinol , vol.29 , pp. 305
    • Vyhlidal, C.1    Li, X.2    Safe, S.3
  • 29
    • 77953286506 scopus 로고    scopus 로고
    • Lactoferrin: The path from protein to gene
    • Teng CT, Lactoferrin: The path from protein to gene, Biometals, 23 (2010) 359.
    • (2010) Biometals , vol.23 , pp. 359
    • Teng, C.T.1
  • 30
    • 0026554632 scopus 로고    scopus 로고
    • Estrogen response module of the mouse lactoferrin gene contains overlapping chicken ovalbumin upstream promoter transcription factor and estrogen receptorbinding elements
    • Liu Y & Teng CT, Estrogen response module of the mouse lactoferrin gene contains overlapping chicken ovalbumin upstream promoter transcription factor and estrogen receptorbinding elements, Mol Endocrinol, 6 (1996) 355.
    • (1996) Mol Endocrinol , vol.6 , pp. 355
    • Liu, Y.1    Teng, C.T.2
  • 33
    • 77956396298 scopus 로고    scopus 로고
    • Identification of toxicological biomarkers of di(2-ethylhexyl) phthalate in proteins secreted by HepG2 cells using proteomic analysis
    • Choi S, Park SY, Jeong J, Cho E, Phark S, Lee M, Kwak D, Lim JY, Jung WW & Sul D, Identification of toxicological biomarkers of di(2-ethylhexyl) phthalate in proteins secreted by HepG2 cells using proteomic analysis, Proteomics, 10 (2010) 1831.
    • (2010) Proteomics , vol.10 , pp. 1831
    • Choi, S.1    Park, S.Y.2    Jeong, J.3    Cho, E.4    Phark, S.5    Lee, M.6    Kwak, D.7    Lim, J.Y.8    Jung, W.W.9    Sul, D.10
  • 34
    • 0036667379 scopus 로고    scopus 로고
    • Downregulation of lactoferrin by PPARα ligands: Role in perturbation of hepatocyte proliferation and apoptosis
    • Hasmall S, Orphanides G, James N, Pennie W, Hedley K, Soames A, Kimber I & Roberts R, Downregulation of lactoferrin by PPARα ligands: Role in perturbation of hepatocyte proliferation and apoptosis, Toxicol Sci, 68 (2002) 304.
    • (2002) Toxicol Sci , vol.68 , pp. 304
    • Hasmall, S.1    Orphanides, G.2    James, N.3    Pennie, W.4    Hedley, K.5    Soames, A.6    Kimber, I.7    Roberts, R.8
  • 36
    • 0036005888 scopus 로고    scopus 로고
    • Tumor necrosis factor or tumor promoting factor?
    • Balkwill F, Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor, 13 (2002) 135.
    • (2002) Cytokine Growth Factor , vol.13 , pp. 135
    • Balkwill, F.1
  • 37
    • 0027515007 scopus 로고
    • Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo
    • Machnicki M, Zimecki M & Zagulski T, Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo, Int J Exp Pathol, 74 (1993) 433.
    • (1993) Int J Exp Pathol , vol.74 , pp. 433
    • Machnicki, M.1    Zimecki, M.2    Zagulski, T.3
  • 38
    • 0031959269 scopus 로고    scopus 로고
    • Lactoferrin lowers serum interleukin 6 and tumor necrosis factor alpha levels in mice subjected to surgery
    • Zimecki M, Właszczyk A, Zagulski T & Kübler A, Lactoferrin lowers serum interleukin 6 and tumor necrosis factor alpha levels in mice subjected to surgery, Arch Immunol Ther Exp, 42 (1998) 97.
    • (1998) Arch Immunol Ther Exp , vol.42 , pp. 97
    • Zimecki, M.1    Właszczyk, A.2    Zagulski, T.3    Kübler, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.