Toxicity profile of lisdexamfetamine dimesylate in three independent rat toxicology studies

Basic and Clinical Pharmacology and Toxicology

Volumn 101, Issue 4, 2007, Pages 231-240

  Krishnan, Suma ^a   Montcrief, Scott ^a  

^a SHIRE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DEXAMPHETAMINE; LISDEXAMFETAMINE; NITROGEN; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOMUTILATION; BRAIN WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG ELIMINATION; DRUG FATALITY; DRUG HALF LIFE; DRUG MEGADOSE; FEMALE; HEART WEIGHT; HISTOPATHOLOGY; LD 50; LIVER WEIGHT; MALE; MOTOR ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SPLEEN WEIGHT; TOXICITY TESTING; TOXICOKINETICS; UREA NITROGEN BLOOD LEVEL;

ACUTE TOXICITY TESTS; ADMINISTRATION, ORAL; ANIMALS; BLOOD CHEMICAL ANALYSIS; CENTRAL NERVOUS SYSTEM STIMULANTS; DEXTROAMPHETAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; LETHAL DOSE 50; MALE; ORGAN SIZE; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; SELF MUTILATION; TOXICITY TESTS, CHRONIC;

RATTUS;

EID: 36649028135     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2007.00093.x     Document Type: Article

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