Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 43, 2014, Pages 15579-15584

  Lindsay, Ken J ^a   Du, Jianhai ^a   Sloat, Stephanie R ^a   Contreras, Laura ^b   Linton, Jonathan D ^a   Turner, Sally J ^a   Sadilek, Martin ^c   Satrústegui, Jorgina ^b   Hurley, James B ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Aerobic glycolysis; Glutamine metabolism; M ller glia; Photoreceptors; Retina

Indexed keywords

ASPARTATE GLUTAMATE CARRIER 1; ASPARTIC ACID; CARRIER PROTEIN; GLYCOLYTIC ENZYME; LACTIC ACID; MALIC ACID; PYRUVATE KINASE; UNCLASSIFIED DRUG; AMINO ACID TRANSPORTER; ANTIPORTER; ASPARTATE-GLUTAMATE CARRIER; CARBON; GLUCOSE; GLUTAMINE; ISOENZYME; LACTOSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GAS LIQUID CHROMATOGRAPHY; GLIA CELL; GLYCOLYSIS; HUMAN; HUMAN CELL; METABOLITE; MUELLER CELL; NERVE CELL; NONHUMAN; PHOTORECEPTOR CELL; PROTEIN EXPRESSION; RAT; RETINA; SYMBIOSIS; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; GLIA; HELA CELL LINE; LIGHT; MACROGLIA; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; RADIATION RESPONSE; RETINA NERVE CELL;

AMINO ACID TRANSPORT SYSTEMS, ACIDIC; ANIMALS; ANTIPORTERS; ASPARTIC ACID; CARBON ISOTOPES; CELLS, CULTURED; EPENDYMOGLIAL CELLS; GLUCOSE; GLUTAMINE; GLYCOLYSIS; HELA CELLS; HUMANS; ISOENZYMES; LACTOSE; LIGHT; MICE; MODELS, BIOLOGICAL; NEUROGLIA; OXIDATION-REDUCTION; PHOTORECEPTOR CELLS, VERTEBRATE; PYRUVATE KINASE; RETINAL NEURONS;

EID: 84908518423     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1412441111     Document Type: Article

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