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Volumn 16, Issue 10, 2014, Pages 1345-1360

Bone marrow-derived mesenchymal stromal cells improve vascular regeneration and reduce leukocyte-endothelium activation in critical ischemic murine skin in a dose-dependent manner

Author keywords

Angiogenesis; Arteriogenesis; Conditioned medium; Immunomodulation; Mesenchymal stromal cells; Paracrine function; Vascular regeneration

Indexed keywords

ANGIOPOIETIN 2; CHEMOKINE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE CHEMOATTRACTANT; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84908512584     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2014.05.008     Document Type: Article
Times cited : (23)

References (81)
  • 1
    • 77955820309 scopus 로고    scopus 로고
    • Concise review: hitting the right spot with mesenchymal stromal cells
    • Tolar J., Le Blanc K., Keating A., Blazar B.R. Concise review: hitting the right spot with mesenchymal stromal cells. Stem Cells 2010, 28:1446-1455.
    • (2010) Stem Cells , vol.28 , pp. 1446-1455
    • Tolar, J.1    Le Blanc, K.2    Keating, A.3    Blazar, B.R.4
  • 2
    • 58449135981 scopus 로고    scopus 로고
    • Why are MSCs therapeutic? New data: new insight
    • Caplan A.I. Why are MSCs therapeutic? New data: new insight. JPathol 2009, 217:318-324.
    • (2009) JPathol , vol.217 , pp. 318-324
    • Caplan, A.I.1
  • 3
    • 79959951133 scopus 로고    scopus 로고
    • The MSC: an injury drugstore
    • Caplan A.I., Correa D. The MSC: an injury drugstore. Cell Stem Cell 2011, 9:11-15.
    • (2011) Cell Stem Cell , vol.9 , pp. 11-15
    • Caplan, A.I.1    Correa, D.2
  • 4
    • 0035075998 scopus 로고    scopus 로고
    • Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats
    • Chen J., Li Y., Wang L., Zhang Z., Lu D., Lu M., et al. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 2001, 32:1005-1011.
    • (2001) Stroke , vol.32 , pp. 1005-1011
    • Chen, J.1    Li, Y.2    Wang, L.3    Zhang, Z.4    Lu, D.5    Lu, M.6
  • 5
    • 33846639224 scopus 로고    scopus 로고
    • Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftment
    • Iso Y., Spees J.L., Serrano C., Bakondi B., Pochampally R., Song Y., et al. Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftment. Biochem Biophys Res Commun 2007, 354:700-706.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 700-706
    • Iso, Y.1    Spees, J.L.2    Serrano, C.3    Bakondi, B.4    Pochampally, R.5    Song, Y.6
  • 6
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • Kinnaird T., Stabile E., Burnett M.S., Lee C.W., Barr S., Fuchs S., et al. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 2004, 94:678-685.
    • (2004) Circ Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Lee, C.W.4    Barr, S.5    Fuchs, S.6
  • 7
    • 34547670282 scopus 로고    scopus 로고
    • Paracrine effects of direct intramyocardial implantation of bone marrow derived cells to enhance neovascularization in chronic ischaemic myocardium
    • Tse H., Siu C., Zhu S., Songyan L., Zhang Q., Lai W., et al. Paracrine effects of direct intramyocardial implantation of bone marrow derived cells to enhance neovascularization in chronic ischaemic myocardium. Eur J Heart Failure 2007, 9:747-753.
    • (2007) Eur J Heart Failure , vol.9 , pp. 747-753
    • Tse, H.1    Siu, C.2    Zhu, S.3    Songyan, L.4    Zhang, Q.5    Lai, W.6
  • 8
    • 80052933197 scopus 로고    scopus 로고
    • Basic and therapeutic aspects of angiogenesis
    • Potente M., Gerhardt H., Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell 2011, 146:873-887.
    • (2011) Cell , vol.146 , pp. 873-887
    • Potente, M.1    Gerhardt, H.2    Carmeliet, P.3
  • 9
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005, 438:932-936.
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 10
    • 84867230063 scopus 로고    scopus 로고
    • Effects of bone marrow mesenchymal stem cells in a rat model of myocardial infarction
    • Wang T., Sun S., Wan Z., Weil M.H., Tang W. Effects of bone marrow mesenchymal stem cells in a rat model of myocardial infarction. Resuscitation 2012, 83:1391-1396.
    • (2012) Resuscitation , vol.83 , pp. 1391-1396
    • Wang, T.1    Sun, S.2    Wan, Z.3    Weil, M.H.4    Tang, W.5
  • 11
    • 0033565540 scopus 로고    scopus 로고
    • VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells
    • Asahara T., Takahashi T., Masuda H., Kalka C., Chen D., Iwaguro H., et al. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 1999, 18:3964-3972.
    • (1999) EMBO J , vol.18 , pp. 3964-3972
    • Asahara, T.1    Takahashi, T.2    Masuda, H.3    Kalka, C.4    Chen, D.5    Iwaguro, H.6
  • 12
    • 1842486565 scopus 로고    scopus 로고
    • Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms
    • Kinnaird T., Stabile E., Burnett M.S., Shou M., Lee C.W., Barr S., et al. Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 2004, 109:1543-1549.
    • (2004) Circulation , vol.109 , pp. 1543-1549
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Shou, M.4    Lee, C.W.5    Barr, S.6
  • 13
    • 84859488945 scopus 로고    scopus 로고
    • Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin
    • Schlosser S., Dennler C., Eberli D., Schweizer R. Paracrine effects of mesenchymal stem cells enhance vascular regeneration in ischemic murine skin. Microvasc Res 2012, 83:267-275.
    • (2012) Microvasc Res , vol.83 , pp. 267-275
    • Schlosser, S.1    Dennler, C.2    Eberli, D.3    Schweizer, R.4
  • 14
    • 84866182681 scopus 로고    scopus 로고
    • Mesenchymal stem cells secrete multiple cytokines that promote angiogenesis and have contrasting effects on chemotaxis and apoptosis
    • Boomsma R.A., Geenen D.L. Mesenchymal stem cells secrete multiple cytokines that promote angiogenesis and have contrasting effects on chemotaxis and apoptosis. PloS One 2012, 7:e35685.
    • (2012) PloS One , vol.7 , pp. e35685
    • Boomsma, R.A.1    Geenen, D.L.2
  • 15
    • 34848874465 scopus 로고    scopus 로고
    • The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF
    • Sadat S., Gehmert S., Song Y.H., Yen Y., Bai X., Gaiser S., et al. The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF. Biochem Biophys Res Commun 2007, 363:674-679.
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 674-679
    • Sadat, S.1    Gehmert, S.2    Song, Y.H.3    Yen, Y.4    Bai, X.5    Gaiser, S.6
  • 16
    • 33644805745 scopus 로고    scopus 로고
    • Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells
    • Nakagami H., Maeda K., Morishita R., Iguchi S., Nishikawa T., Takami Y., et al. Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vasc Biol 2005, 25:2542-2547.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2542-2547
    • Nakagami, H.1    Maeda, K.2    Morishita, R.3    Iguchi, S.4    Nishikawa, T.5    Takami, Y.6
  • 17
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
    • Gale N.W., Yancopoulos G.D. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev 1999, 13:1055-1066.
    • (1999) Genes Dev , vol.13 , pp. 1055-1066
    • Gale, N.W.1    Yancopoulos, G.D.2
  • 18
    • 55449131657 scopus 로고    scopus 로고
    • Angiopoietin-2 stimulates blood flow recovery after femoral artery occlusion by inducing inflammation and arteriogenesis
    • Tressel S.L., Kim H., Ni C., Chang K., Velasquez-Castano J.C., Taylor W.R., et al. Angiopoietin-2 stimulates blood flow recovery after femoral artery occlusion by inducing inflammation and arteriogenesis. Arterioscl Thromb Vasc Biol 2008, 28:1989-1995.
    • (2008) Arterioscl Thromb Vasc Biol , vol.28 , pp. 1989-1995
    • Tressel, S.L.1    Kim, H.2    Ni, C.3    Chang, K.4    Velasquez-Castano, J.C.5    Taylor, W.R.6
  • 19
    • 84866688637 scopus 로고    scopus 로고
    • Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2
    • Lekas M., Lekas P., Mei S.H., Deng Y., Dumont D.J., Stewart D.J. Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2. PloS One 2012, 7:e43568.
    • (2012) PloS One , vol.7 , pp. e43568
    • Lekas, M.1    Lekas, P.2    Mei, S.H.3    Deng, Y.4    Dumont, D.J.5    Stewart, D.J.6
  • 20
    • 79751504754 scopus 로고    scopus 로고
    • Mesenchymal stem cells: mechanisms of inflammation
    • Singer N.G., Caplan A.I. Mesenchymal stem cells: mechanisms of inflammation. Annu Rev Pathol 2011, 6:1-24.
    • (2011) Annu Rev Pathol , vol.6 , pp. 1-24
    • Singer, N.G.1    Caplan, A.I.2
  • 22
    • 23944519424 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
    • Zappia E., Casazza S., Pedemonte E., Benvenuto F., Bonanni I., Gerdoni E., et al. Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. Blood 2005, 106:1755-1761.
    • (2005) Blood , vol.106 , pp. 1755-1761
    • Zappia, E.1    Casazza, S.2    Pedemonte, E.3    Benvenuto, F.4    Bonanni, I.5    Gerdoni, E.6
  • 23
    • 84867810334 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome
    • Xu J., Wang D., Liu D., Fan Z., Zhang H., Liu O., et al. Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome. Blood 2012, 120:3142-3151.
    • (2012) Blood , vol.120 , pp. 3142-3151
    • Xu, J.1    Wang, D.2    Liu, D.3    Fan, Z.4    Zhang, H.5    Liu, O.6
  • 24
  • 25
    • 81855177169 scopus 로고    scopus 로고
    • Modulation of immune response and T-cell regulation by donor adipose-derived stem cells in a rodent hind-limb allotransplant model
    • Kuo Y.R., Chen C.C., Goto S., Lee I.T., Huang C.W., Tsai C.C., et al. Modulation of immune response and T-cell regulation by donor adipose-derived stem cells in a rodent hind-limb allotransplant model. Plast Reconstr Surg 2011, 128:661e-672e.
    • (2011) Plast Reconstr Surg , vol.128 , pp. 661e-672e
    • Kuo, Y.R.1    Chen, C.C.2    Goto, S.3    Lee, I.T.4    Huang, C.W.5    Tsai, C.C.6
  • 26
    • 84862281756 scopus 로고    scopus 로고
    • Markers for characterization of bone marrow multipotential stromal cells
    • Boxall S.A., Jones E. Markers for characterization of bone marrow multipotential stromal cells. Stem Cells Int 2012, 2012:975871.
    • (2012) Stem Cells Int , vol.2012 , pp. 975871
    • Boxall, S.A.1    Jones, E.2
  • 27
    • 84872498915 scopus 로고    scopus 로고
    • Cardiac stem cell therapy to modulate inflammation upon myocardial infarction
    • Akker F., Deddens J.C., Doevendans P.A., Sluijter J.P. Cardiac stem cell therapy to modulate inflammation upon myocardial infarction. Biochim Biophys Acta 2012, 1830:2449-2458.
    • (2012) Biochim Biophys Acta , vol.1830 , pp. 2449-2458
    • Akker, F.1    Deddens, J.C.2    Doevendans, P.A.3    Sluijter, J.P.4
  • 29
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
    • Lee R.H., Pulin A.A., Seo M.J., Kota D.J., Ylostalo J., Larson B.L., et al. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 2009, 5:54-63.
    • (2009) Cell Stem Cell , vol.5 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3    Kota, D.J.4    Ylostalo, J.5    Larson, B.L.6
  • 30
    • 0037055666 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial
    • Tateishi-Yuyama E., Matsubara H., Murohara T., Ikeda U., Shintani S., Masaki H., et al. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet 2002, 360:427-435.
    • (2002) Lancet , vol.360 , pp. 427-435
    • Tateishi-Yuyama, E.1    Matsubara, H.2    Murohara, T.3    Ikeda, U.4    Shintani, S.5    Masaki, H.6
  • 31
    • 80052325733 scopus 로고    scopus 로고
    • Improved mobilization of the CD34(+) and CD133(+) bone marrow-derived circulating progenitor cells by freshly isolated intracoronary bone marrow cell transplantation in patients with ischemic heart disease
    • Turan R.G., Bozdag-Turan I., Ortak J., Akin I., Kische S., Schneider H., et al. Improved mobilization of the CD34(+) and CD133(+) bone marrow-derived circulating progenitor cells by freshly isolated intracoronary bone marrow cell transplantation in patients with ischemic heart disease. Stem Cells Dev 2011, 20:1491-1501.
    • (2011) Stem Cells Dev , vol.20 , pp. 1491-1501
    • Turan, R.G.1    Bozdag-Turan, I.2    Ortak, J.3    Akin, I.4    Kische, S.5    Schneider, H.6
  • 32
    • 3042710733 scopus 로고    scopus 로고
    • Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial
    • Wollert K.C., Meyer G.P., Lotz J., Ringes-Lichtenberg S., Lippolt P., Breidenbach C., et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004, 364:141-148.
    • (2004) Lancet , vol.364 , pp. 141-148
    • Wollert, K.C.1    Meyer, G.P.2    Lotz, J.3    Ringes-Lichtenberg, S.4    Lippolt, P.5    Breidenbach, C.6
  • 34
    • 84875070796 scopus 로고    scopus 로고
    • Stem cell derived endothelial cells for cardiovascular disease; a therapeutic perspective
    • Reed D.M., Foldes G., Harding S.E., Mitchell J.A. Stem cell derived endothelial cells for cardiovascular disease; a therapeutic perspective. Br J Clin Pharmacol 2013, 75:897-906.
    • (2013) Br J Clin Pharmacol , vol.75 , pp. 897-906
    • Reed, D.M.1    Foldes, G.2    Harding, S.E.3    Mitchell, J.A.4
  • 35
    • 60849136593 scopus 로고    scopus 로고
    • Mesenchymal stem cell homing: the devil is in the details
    • Karp J.M., Teo G.S. Mesenchymal stem cell homing: the devil is in the details. Cell Stem Cell 2009, 4:206-216.
    • (2009) Cell Stem Cell , vol.4 , pp. 206-216
    • Karp, J.M.1    Teo, G.S.2
  • 36
    • 77951444290 scopus 로고    scopus 로고
    • Time-dependent migration of systemically delivered bone marrow mesenchymal stem cells to the infarcted heart
    • Assis A.C., Carvalho J.L., Jacoby B.A., Ferreira R.L., Castanheira P., Diniz S.O., et al. Time-dependent migration of systemically delivered bone marrow mesenchymal stem cells to the infarcted heart. Cell Transplant 2010, 19:219-230.
    • (2010) Cell Transplant , vol.19 , pp. 219-230
    • Assis, A.C.1    Carvalho, J.L.2    Jacoby, B.A.3    Ferreira, R.L.4    Castanheira, P.5    Diniz, S.O.6
  • 38
    • 84872914245 scopus 로고    scopus 로고
    • Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion
    • Eggenhofer E., Benseler V., Kroemer A., Popp F.C., Geissler E.K., Schlitt H.J., et al. Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion. Front Immunol 2012, 3:297.
    • (2012) Front Immunol , vol.3 , pp. 297
    • Eggenhofer, E.1    Benseler, V.2    Kroemer, A.3    Popp, F.C.4    Geissler, E.K.5    Schlitt, H.J.6
  • 39
    • 66249097415 scopus 로고    scopus 로고
    • Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantation
    • Santo S., Yang Z., Ballmoos M.W., Voelzmann J., Diehm N., Baumgartner I., et al. Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantation. PloS One 2009, 4:e5643.
    • (2009) PloS One , vol.4 , pp. e5643
    • Santo, S.1    Yang, Z.2    Ballmoos, M.W.3    Voelzmann, J.4    Diehm, N.5    Baumgartner, I.6
  • 40
    • 34748845732 scopus 로고    scopus 로고
    • Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis
    • Hung S.C., Pochampally R.R., Chen S.C., Hsu S.C., Prockop D.J. Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis. Stem Cells 2007, 25:2363-2370.
    • (2007) Stem Cells , vol.25 , pp. 2363-2370
    • Hung, S.C.1    Pochampally, R.R.2    Chen, S.C.3    Hsu, S.C.4    Prockop, D.J.5
  • 41
    • 84863884154 scopus 로고    scopus 로고
    • Conditioned media from mesenchymal stem cells enhanced bone regeneration in rat calvarial bone defects
    • Osugi M., Katagiri W., Yoshimi R., Inukai T., Hibi H., Ueda M. Conditioned media from mesenchymal stem cells enhanced bone regeneration in rat calvarial bone defects. Tissue Eng Part A 2012, 18:1479-1489.
    • (2012) Tissue Eng Part A , vol.18 , pp. 1479-1489
    • Osugi, M.1    Katagiri, W.2    Yoshimi, R.3    Inukai, T.4    Hibi, H.5    Ueda, M.6
  • 42
    • 0033559266 scopus 로고    scopus 로고
    • Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation
    • Phinney D.G., Kopen G., Isaacson R.L., Prockop D.J. Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation. JCell Biochem 1999, 72:570-585.
    • (1999) JCell Biochem , vol.72 , pp. 570-585
    • Phinney, D.G.1    Kopen, G.2    Isaacson, R.L.3    Prockop, D.J.4
  • 43
    • 80155135685 scopus 로고    scopus 로고
    • Morphology and hemodynamics during vascular regeneration in critically ischemic murine skin studied by intravital microscopy techniques
    • Schweizer R., Merz K., Schlosser S., Spanholtz T., Contaldo C., Stein J.V., et al. Morphology and hemodynamics during vascular regeneration in critically ischemic murine skin studied by intravital microscopy techniques. Eur Surg Res 2011, 47:222-230.
    • (2011) Eur Surg Res , vol.47 , pp. 222-230
    • Schweizer, R.1    Merz, K.2    Schlosser, S.3    Spanholtz, T.4    Contaldo, C.5    Stein, J.V.6
  • 44
    • 77955983297 scopus 로고    scopus 로고
    • The choice of anesthesia influences oxidative energy metabolism and tissue survival in critically ischemic murine skin
    • Schlosser S., Spanholtz T., Merz K., Dennler C., Banic A., Erni D., et al. The choice of anesthesia influences oxidative energy metabolism and tissue survival in critically ischemic murine skin. JSurg Res 2010, 162:308-313.
    • (2010) JSurg Res , vol.162 , pp. 308-313
    • Schlosser, S.1    Spanholtz, T.2    Merz, K.3    Dennler, C.4    Banic, A.5    Erni, D.6
  • 45
    • 0032851428 scopus 로고    scopus 로고
    • Quantitative assessment of microhemodynamics in ischemic skin flap tissue by intravital microscopy
    • discussion 14-5
    • Erni D., Sakai H., Banic A., Tschopp H.M., Intaglietta M. Quantitative assessment of microhemodynamics in ischemic skin flap tissue by intravital microscopy. Ann Plast Surg 1999, 43:405-414. discussion 14-5.
    • (1999) Ann Plast Surg , vol.43 , pp. 405-414
    • Erni, D.1    Sakai, H.2    Banic, A.3    Tschopp, H.M.4    Intaglietta, M.5
  • 46
    • 33947186447 scopus 로고    scopus 로고
    • Hemoglobin vesicles reduce hypoxia-related inflammation in critically ischemic hamster flap tissue
    • Plock J.A., Tromp A.E., Contaldo C., Spanholtz T., Sinovcic D., Sakai H., et al. Hemoglobin vesicles reduce hypoxia-related inflammation in critically ischemic hamster flap tissue. Crit Care Med 2007, 35:899-905.
    • (2007) Crit Care Med , vol.35 , pp. 899-905
    • Plock, J.A.1    Tromp, A.E.2    Contaldo, C.3    Spanholtz, T.4    Sinovcic, D.5    Sakai, H.6
  • 47
    • 0031171594 scopus 로고    scopus 로고
    • [Cap-Image-a new kind of computer-assisted video image analysis system for dynamic capillary microscopy]
    • [in German]
    • Klyscz T., Jünger M., Jung F., Zeintl H. [Cap-Image-a new kind of computer-assisted video image analysis system for dynamic capillary microscopy]. Biomed Tech (Berl) 1997, 42:168-175. [in German].
    • (1997) Biomed Tech (Berl) , vol.42 , pp. 168-175
    • Klyscz, T.1    Jünger, M.2    Jung, F.3    Zeintl, H.4
  • 48
    • 28144460797 scopus 로고    scopus 로고
    • Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?
    • Plock J.A., Contaldo C., Sakai H., Tsuchida E., Leunig M., Banic A., et al. Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?. Am J Physiol Heart Circ Physiol 2005, 289:H2624-H2631.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. H2624-H2631
    • Plock, J.A.1    Contaldo, C.2    Sakai, H.3    Tsuchida, E.4    Leunig, M.5    Banic, A.6
  • 49
    • 84995335174 scopus 로고    scopus 로고
    • Correlation between expression of P38 MAPK-signaling and uPA in breast cancer
    • Han Y., Liu L., Yan D., Wang G. Correlation between expression of P38 MAPK-signaling and uPA in breast cancer. Chin J Clin Oncol 2008, 5:161-164.
    • (2008) Chin J Clin Oncol , vol.5 , pp. 161-164
    • Han, Y.1    Liu, L.2    Yan, D.3    Wang, G.4
  • 50
    • 78649329575 scopus 로고    scopus 로고
    • Dose-dependent systolic contribution of differentiated stem cells in post-infarct ventricular function
    • Shim W.S., Tan G., Gu Y., Qian L., Li S., Chung Y.Y., et al. Dose-dependent systolic contribution of differentiated stem cells in post-infarct ventricular function. JHeart Lung Transpl 2010, 29:1415-1426.
    • (2010) JHeart Lung Transpl , vol.29 , pp. 1415-1426
    • Shim, W.S.1    Tan, G.2    Gu, Y.3    Qian, L.4    Li, S.5    Chung, Y.Y.6
  • 51
    • 84878141282 scopus 로고    scopus 로고
    • [Transplantation of adipose tissue-derived stem cells promotes soft tissue wound repair in rats]
    • [inChinese]
    • Nan H., Gao J.H., Lu F., Fu B.C. [Transplantation of adipose tissue-derived stem cells promotes soft tissue wound repair in rats]. Nan Fang Yi Ke Da Xue Xue Bao 2010, 30:2633-2636. [inChinese].
    • (2010) Nan Fang Yi Ke Da Xue Xue Bao , vol.30 , pp. 2633-2636
    • Nan, H.1    Gao, J.H.2    Lu, F.3    Fu, B.C.4
  • 52
    • 44349145552 scopus 로고    scopus 로고
    • Intravenously administered bone marrow cells migrate to damaged brain tissue and improve neural function in ischemic rats
    • Wu J., Sun Z., Sun H.S., Weisel R.D., Keating A., Li Z.H., et al. Intravenously administered bone marrow cells migrate to damaged brain tissue and improve neural function in ischemic rats. Cell Transplant 2008, 16:993-1005.
    • (2008) Cell Transplant , vol.16 , pp. 993-1005
    • Wu, J.1    Sun, Z.2    Sun, H.S.3    Weisel, R.D.4    Keating, A.5    Li, Z.H.6
  • 53
    • 33845992844 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-3 is a myocardial mesenchymal stem cell homing factor
    • Schenk S., Mal N., Finan A., Zhang M., Kiedrowski M., Popovic Z., et al. Monocyte chemotactic protein-3 is a myocardial mesenchymal stem cell homing factor. Stem Cells 2007, 25:245-251.
    • (2007) Stem Cells , vol.25 , pp. 245-251
    • Schenk, S.1    Mal, N.2    Finan, A.3    Zhang, M.4    Kiedrowski, M.5    Popovic, Z.6
  • 54
    • 53049098859 scopus 로고    scopus 로고
    • Optimization of a therapeutic protocol for intravenous injection of human mesenchymal stem cells after cerebral ischemia in adult rats
    • Omori Y., Honmou O., Harada K., Suzuki J., Houkin K., Kocsis J.D. Optimization of a therapeutic protocol for intravenous injection of human mesenchymal stem cells after cerebral ischemia in adult rats. Brain Res 2008, 1236:30-38.
    • (2008) Brain Res , vol.1236 , pp. 30-38
    • Omori, Y.1    Honmou, O.2    Harada, K.3    Suzuki, J.4    Houkin, K.5    Kocsis, J.D.6
  • 55
    • 4444312162 scopus 로고    scopus 로고
    • Influence of mechanical, cellular, and molecular factors on collateral artery growth (arteriogenesis)
    • Heil M., Schaper W. Influence of mechanical, cellular, and molecular factors on collateral artery growth (arteriogenesis). Circ Res 2004, 95:449-458.
    • (2004) Circ Res , vol.95 , pp. 449-458
    • Heil, M.1    Schaper, W.2
  • 56
    • 84856793345 scopus 로고    scopus 로고
    • Distinct microhemodynamic efficacy of arteriogenesis and angiogenesis in critically ischemic skin flaps
    • Merz K., Schlosser S., Giovanoli P., Schweizer R. Distinct microhemodynamic efficacy of arteriogenesis and angiogenesis in critically ischemic skin flaps. Microvascular 2012, 83:249-256.
    • (2012) Microvascular , vol.83 , pp. 249-256
    • Merz, K.1    Schlosser, S.2    Giovanoli, P.3    Schweizer, R.4
  • 57
    • 3242695063 scopus 로고    scopus 로고
    • Improvement of postnatal neovascularization by human adipose tissue-derived stem cells
    • Miranville A., Heeschen C., Sengenes C., Curat C.A., Busse R., Bouloumie A. Improvement of postnatal neovascularization by human adipose tissue-derived stem cells. Circulation 2004, 110:349-355.
    • (2004) Circulation , vol.110 , pp. 349-355
    • Miranville, A.1    Heeschen, C.2    Sengenes, C.3    Curat, C.A.4    Busse, R.5    Bouloumie, A.6
  • 59
    • 84880943141 scopus 로고    scopus 로고
    • Acomparison of the reparative and angiogenic properties of mesenchymal stem cells derived from the bone marrow of BALB/c and C57/BL6 mice in a model of limb ischemia
    • Cunha F.F., Martins L., Martin P.K., Stilhano R.S., Han S.W. Acomparison of the reparative and angiogenic properties of mesenchymal stem cells derived from the bone marrow of BALB/c and C57/BL6 mice in a model of limb ischemia. Stem Cell Res Ther 2013, 4:86.
    • (2013) Stem Cell Res Ther , vol.4 , pp. 86
    • Cunha, F.F.1    Martins, L.2    Martin, P.K.3    Stilhano, R.S.4    Han, S.W.5
  • 60
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nature Med 2000, 6:389-395.
    • (2000) Nature Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 61
    • 84861820220 scopus 로고    scopus 로고
    • Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling
    • Felcht M., Luck R., Schering A., Seidel P., Srivastava K., Hu J., et al. Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling. JClin Invest 2012, 122:1991-2005.
    • (2012) JClin Invest , vol.122 , pp. 1991-2005
    • Felcht, M.1    Luck, R.2    Schering, A.3    Seidel, P.4    Srivastava, K.5    Hu, J.6
  • 62
    • 84882679528 scopus 로고    scopus 로고
    • Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGFβ1 in diabetic eyes undergoing vitrectomy
    • Loukovaara S., Robciuc A., Holopainen J.M., Lehti K., Pessi T., Liinamaa J., et al. Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGFβ1 in diabetic eyes undergoing vitrectomy. Acta Ophthalmol 2013, 91:531-539.
    • (2013) Acta Ophthalmol , vol.91 , pp. 531-539
    • Loukovaara, S.1    Robciuc, A.2    Holopainen, J.M.3    Lehti, K.4    Pessi, T.5    Liinamaa, J.6
  • 63
    • 67650753834 scopus 로고    scopus 로고
    • The role of the angiopoietins in vascular morphogenesis
    • Thomas M., Augustin H.G. The role of the angiopoietins in vascular morphogenesis. Angiogenesis 2009, 12:125-137.
    • (2009) Angiogenesis , vol.12 , pp. 125-137
    • Thomas, M.1    Augustin, H.G.2
  • 64
    • 0035121532 scopus 로고    scopus 로고
    • Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness
    • Korff T., Kimmina S., Martiny-Baron G., Augustin H.G. Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. FASEB J 2001, 15:447-457.
    • (2001) FASEB J , vol.15 , pp. 447-457
    • Korff, T.1    Kimmina, S.2    Martiny-Baron, G.3    Augustin, H.G.4
  • 65
    • 77953685336 scopus 로고    scopus 로고
    • Enhanced cell therapy strategy to treat chronic limb-threatening ischemia
    • Eton D., Yu H. Enhanced cell therapy strategy to treat chronic limb-threatening ischemia. JVasc Surg 2010, 52:199-204.
    • (2010) JVasc Surg , vol.52 , pp. 199-204
    • Eton, D.1    Yu, H.2
  • 66
    • 9444292842 scopus 로고    scopus 로고
    • Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction
    • Kawada H., Fujita J., Kinjo K., Matsuzaki Y., Tsuma M., Miyatake H., et al. Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood 2004, 104:3581-3587.
    • (2004) Blood , vol.104 , pp. 3581-3587
    • Kawada, H.1    Fujita, J.2    Kinjo, K.3    Matsuzaki, Y.4    Tsuma, M.5    Miyatake, H.6
  • 68
    • 37549045010 scopus 로고    scopus 로고
    • Late-outgrowth endothelial cells attenuate intimal hyperplasia contributed by mesenchymal stem cells after vascular injury
    • Wang C.H., Cherng W.J., Yang N.I., Kuo L.T., Hsu C.M., Yeh H.I., et al. Late-outgrowth endothelial cells attenuate intimal hyperplasia contributed by mesenchymal stem cells after vascular injury. Arterioscler Thromb Vasc Biol 2008, 28:54-60.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 54-60
    • Wang, C.H.1    Cherng, W.J.2    Yang, N.I.3    Kuo, L.T.4    Hsu, C.M.5    Yeh, H.I.6
  • 69
    • 80054958024 scopus 로고    scopus 로고
    • Concise review: circulating endothelial progenitor cells for vascular medicine
    • Asahara T., Kawamoto A., Masuda H. Concise review: circulating endothelial progenitor cells for vascular medicine. Stem Cells 2011, 29:1650-1655.
    • (2011) Stem Cells , vol.29 , pp. 1650-1655
    • Asahara, T.1    Kawamoto, A.2    Masuda, H.3
  • 70
    • 53249095498 scopus 로고    scopus 로고
    • The immune system and cardiac repair
    • Frangogiannis N.G. The immune system and cardiac repair. Pharmacol Res 2008, 58:88-111.
    • (2008) Pharmacol Res , vol.58 , pp. 88-111
    • Frangogiannis, N.G.1
  • 71
    • 1942437470 scopus 로고    scopus 로고
    • Inflammation- and ischemia-induced shedding of venular glycocalyx
    • Mulivor A.W., Lipowsky H.H. Inflammation- and ischemia-induced shedding of venular glycocalyx. Am J Physiol Heart Circ Physiol 2004, 286:H1672-H1680.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , pp. H1672-H1680
    • Mulivor, A.W.1    Lipowsky, H.H.2
  • 72
    • 80053282797 scopus 로고    scopus 로고
    • Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock
    • Pati S., Gerber M.H., Menge T.D., Wataha K.A., Zhao Y., Baumgartner J.A., et al. Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PloS One 2011, 6:e25171.
    • (2011) PloS One , vol.6 , pp. e25171
    • Pati, S.1    Gerber, M.H.2    Menge, T.D.3    Wataha, K.A.4    Zhao, Y.5    Baumgartner, J.A.6
  • 73
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S., Pittenger M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005, 105:1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 74
    • 34247619261 scopus 로고    scopus 로고
    • Effect of hypoxia on gene expression of bone marrow-derived mesenchymal stem cells and mononuclear cells
    • Ohnishi S., Yasuda T., Kitamura S., Nagaya N. Effect of hypoxia on gene expression of bone marrow-derived mesenchymal stem cells and mononuclear cells. Stem Cells 2007, 25:1166-1177.
    • (2007) Stem Cells , vol.25 , pp. 1166-1177
    • Ohnishi, S.1    Yasuda, T.2    Kitamura, S.3    Nagaya, N.4
  • 75
    • 0036212058 scopus 로고    scopus 로고
    • Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor
    • Thomas J., Liu F., Link D.C. Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor. Curr Opin Hematol 2002, 9:183-189.
    • (2002) Curr Opin Hematol , vol.9 , pp. 183-189
    • Thomas, J.1    Liu, F.2    Link, D.C.3
  • 76
    • 33751544459 scopus 로고    scopus 로고
    • Interleukin-1alpha-induced chemokines in mouse granulosa cells: impact on keratinocyte chemoattractant chemokine, a CXC subfamily
    • Son D.S., Roby K.F. Interleukin-1alpha-induced chemokines in mouse granulosa cells: impact on keratinocyte chemoattractant chemokine, a CXC subfamily. Mol Endocrinol 2006, 20:2999-3013.
    • (2006) Mol Endocrinol , vol.20 , pp. 2999-3013
    • Son, D.S.1    Roby, K.F.2
  • 77
    • 0028076987 scopus 로고
    • Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells
    • Lira S.A., Zalamea P., Heinrich J.N., Fuentes M.E., Carrasco D., Lewin A.C., et al. Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells. JExp Med 1994, 180:2039-2048.
    • (1994) JExp Med , vol.180 , pp. 2039-2048
    • Lira, S.A.1    Zalamea, P.2    Heinrich, J.N.3    Fuentes, M.E.4    Carrasco, D.5    Lewin, A.C.6
  • 78
    • 84855371090 scopus 로고    scopus 로고
    • Regulation of the inflammatory response in cardiac repair
    • Frangogiannis N.G. Regulation of the inflammatory response in cardiac repair. Circ Res 2012, 110:159-173.
    • (2012) Circ Res , vol.110 , pp. 159-173
    • Frangogiannis, N.G.1
  • 79
    • 79955601433 scopus 로고    scopus 로고
    • The emerging role of innate immunity in the heart and vascular system: for whom the cell tolls
    • Mann D.L. The emerging role of innate immunity in the heart and vascular system: for whom the cell tolls. Circ Res 2011, 108:1133-1145.
    • (2011) Circ Res , vol.108 , pp. 1133-1145
    • Mann, D.L.1
  • 80
    • 23844475067 scopus 로고    scopus 로고
    • Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction
    • Amado L.C., Saliaris A.P., Schuleri K.H., St John M., Xie J.S., Cattaneo S., et al. Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. Proc Natl Acad Sci U S A 2005, 102:11474-11479.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11474-11479
    • Amado, L.C.1    Saliaris, A.P.2    Schuleri, K.H.3    St John, M.4    Xie, J.S.5    Cattaneo, S.6
  • 81
    • 0027074215 scopus 로고
    • Microvascular ischemia-reperfusion injury in striated muscle: significance of "reflow paradox"
    • Menger M.D., Pelikan S., Steiner D., Messmer K. Microvascular ischemia-reperfusion injury in striated muscle: significance of "reflow paradox". Am J Physiol 1992, 263:H1901-H1906.
    • (1992) Am J Physiol , vol.263 , pp. H1901-H1906
    • Menger, M.D.1    Pelikan, S.2    Steiner, D.3    Messmer, K.4


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