Fibrosis and renal aging

Kidney International Supplements

Volumn 4, Issue 1, 2014, Pages 75-78

  Yang, Hai Chun ^a   Fogo, Agnes B ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

aging; angiotensin; glomerulosclerosis; PPARg; stem cells

Indexed keywords

ADIPONECTIN; ALDOSTERONE; ANGIOTENSIN 1A RECEPTOR; ANGIOTENSIN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET DERIVED GROWTH FACTOR; RAPAMYCIN; RESVERATROL; SPERMIDINE; TRANSFORMING GROWTH FACTOR BETA;

AGING; ALDOSTERONE BLOOD LEVEL; ARTERIOSCLEROSIS; BONE MARROW CELL; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CALORIC RESTRICTION; CELL AGING; CELL DIFFERENTIATION; CELL TRANSDIFFERENTIATION; DISEASE COURSE; DNA MODIFICATION; GLOMERULOSCLEROSIS; GLOMERULUS FILTRATION RATE; HEMATOPOIETIC STEM CELL; HUMAN; KIDNEY; KIDNEY BLOOD FLOW; KIDNEY FIBROSIS; LIFESPAN; LIPID OXIDATION; LONGEVITY; MULTIPOTENT STEM CELL; NONHUMAN; PLASMA RENIN ACTIVITY; PROTEIN PHOSPHORYLATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SCAR FORMATION; URINARY EXCRETION; WNT SIGNALING PATHWAY;

EID: 84908507176     PISSN: 21571724     EISSN: 21571716     Source Type: Journal    
DOI: 10.1038/kisup.2014.14     Document Type: Short Survey

References (23)

1. Glassock RJ, Winearls C. Ageing and the glomerular filtration rate: truths and consequences. Trans Am Clin Climatol Assoc 2009; 120: 419-428.
2. Zhou XJ, Saxena R, Liu Z et al. Renal senescence in 2008: progress and challenges. Int Urol Nephrol 2008; 40: 823-839.
3. Lopez-Otin C, Blasco MA, Partridge L et al. The hallmarks of aging. Cell 2013; 153: 1194-1217.
4. Zurbig P, Decramer S, Dakna M et al. The human urinary proteome reveals high similarity between kidney aging and chronic kidney disease. Proteomics 2009; 9: 2108-2117.
5. Melk A, Mansfield ES, Hsieh SC et al. Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling. Kidney Int 2005; 68: 2667-2679.
6. Benigni A, Corna D, Zoja C et al. Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest 2009; 119: 524-530.
7. Santos EL, de Picoli Souza K, da Silva ED et al. Long term treatment with ACE inhibitor enalapril decreases body weight gain and increases life span in rats. Biochem Pharmacol 2009; 78: 951-958.
8. Ma LJ, Nakamura S, Aldigier JC et al. Regression of glomerulosclerosis with high-dose angiotensin inhibition is linked to decreased plasminogen activator inhibitor-1. J Am Soc Nephrol 2005; 16: 966-976.
9. Ma LJ, Nakamura S, Whitsitt JS et al. Regression of sclerosis in aging by an angiotensin inhibition-induced decrease in PAI-1. Kidney Int 2000; 58: 2425-2436.
10. Rando TA. Stem cells, ageing and the quest for immortality. Nature 2006; 441: 1080-1086.
11. Yuan R, Peters LL, Paigen B. Mice as a mammalian model for research on the genetics of aging. ILAR J 2011; 52: 4-15.
12. Muller-Sieburg C, Sieburg HB. Stem cell aging: survival of the laziest? Cell Cycle 2008; 7: 3798-3804.
13. Yang HC, Rossini M, Ma LJ et al. Cells derived from young bone marrow alleviate renal aging. J Am Soc Nephrol 2011; 22: 2028-2036.
14. Brack AS, Conboy MJ, Roy S et al. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 2007; 317: 807-810.
15. Liu H, Fergusson MM, Castilho RM et al. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 2007; 317: 803-806.
16. Torres PU, Prie D, Molina-Bletry V et al. Klotho: an antiaging protein involved in mineral and vitamin D metabolism. Kidney Int 2007; 71: 730-737.
17. Sagrinati C, Netti GS, Mazzinghi B et al. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J Am Soc Nephrol 2006; 17: 2443-2456.
18. Zhang J, Hansen KM, Pippin JW et al. De novo expression of podocyte proteins in parietal epithelial cells in experimental aging nephropathy. Am J Physiol Renal Physiol 2012; 302: F571-F580.
19. Harrison DE, Strong R, Sharp ZD et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460: 392-395.
20. Chen C, Liu Y, Zheng P. mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells. Sci Signal 2009; 2: ra75.
21. Shinmura D, Togashi I, Miyoshi S et al. Pretreatment of human mesenchymal stem cells with pioglitazone improved efficiency of cardiomyogenic transdifferentiation and cardiac function. Stem Cells 2011; 29: 357-366.
22. Yang HC, Deleuze S, Zuo Y et al. The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury. J Am Soc Nephrol 2009; 20: 2380-2388.
23. Barbieri M, Bonafe M, Rizzo MR et al. Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity. Exp Gerontol 2004; 39: 1095-1100.