Natural killer cell responses to dendritic cells infected by the ANRS HIV-1 vaccine candidate, MVAHIV

Vaccine

Volumn 32, Issue 43, 2014, Pages 5577-5584

  Cummings, Jean Saville ^a,c   Moreno Nieves, Uriel Y ^a   Arnold, Vincent ^a,d   Gilbert, Adrien ^a   Yarbrough, Kevin ^a   Didier, Celine ^a   Lévy, Yves ^b   Barré Sinoussi, Françoise ^a   Scott Algara, Daniel ^a  

^a INSTITUT PASTEUR   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d INSERM   (France)

Author keywords

Dendritic cell; HIV 1; MVA HIV; NK cell; NKp46

Indexed keywords

GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MODIFIED VACCINIA VIRUS ANKARA HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR NKG2D; UNCLASSIFIED DRUG; CYTOKINE; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; KLRK1 PROTEIN, HUMAN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; NCR1 PROTEIN, HUMAN;

ADAPTIVE IMMUNITY; ANTIGEN EXPRESSION; ARTICLE; CELL INTERACTION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOMEGALOVIRUS INFECTION; DEGRANULATION; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VITRO STUDY; INFECTION CONTROL; INNATE IMMUNITY; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; COCULTURE; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; VIROLOGY;

AIDS VACCINES; CELL DEGRANULATION; COCULTURE TECHNIQUES; CYTOKINES; DENDRITIC CELLS; HIV ANTIGENS; HIV INFECTIONS; HUMANS; KILLER CELLS, NATURAL; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K;

EID: 84908505955     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.07.094     Document Type: Article

References (40)

1. Waggoner S.N., Cornberg M., Selin L.K., Welsh R.M. Natural killer cells act as rheostats modulating antiviral T cells. Nature 2012, 481:394-398.
2. Andrews D.M., Estcourt M.J., Andoniou C.E., Wikstrom M.E., Khong A., Voigt V., et al. Innate immunity defines the capacity of antiviral T cells to limit persistent infection. J Exp Med 2010, 207:1333-1343.
3. Lang P.A., Lang K.S., Xu H.C., Grusdat M., Parish I.A., Recher M., et al. Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity. Proc Natl Acad Sci U S A 2012, 109:1210-1215.
4. Martin M.P., Gao X., Lee J.H., Nelson G.W., Detels R., Goedert J.J., et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat Genet 2002, 31:429-434.
5. Martin M.P., Qi Y., Gao X., Yamada E., Martin J.N., Pereyra F., et al. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Genet 2007, 39:733-740.
6. Jost S., Altfeld M. Evasion from NK cell-mediated immune responses by HIV-1. Microbes Infect 2012, 14:904-915.
7. Scott-Algara D., Truong L.X., Versmisse P., David A., Luong T.T., Nguyen N.V., et al. Cutting edge: increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users. J Immunol 2003, 171:5663-5667.
8. Ravet S., Scott-Algara D., Bonnet E., Tran H.K., Tran T., Nguyen N., et al. Distinctive NK-cell receptor repertoires sustain high-level constitutive NK-cell activation in HIV-exposed uninfected individuals. Blood 2007, 109:4296-4305.
9. Moretta A. Natural killer cells and dendritic cells: rendezvous in abused tissues. Nat Rev Immunol 2002, 2:957-964.
10. Walzer T., Dalod M., Robbins S.H., Zitvogel L., Vivier E. Natural-killer cells and dendritic cells: "l'union fait la force". Blood 2005, 106:2252-2258.
11. Marcenaro E., Carlomagno S., Pesce S., Moretta A., Sivori S. NK/DC crosstalk in anti-viral response. Adv Exp Med Biol 2012, 946:295-308.
12. Alter G., Altfeld M. Mutiny or scrutiny: NK cell modulation of DC function in HIV-1 infection. Trends Immunol 2011, 32:219-224.
13. Terme M., Tomasello E., Maruyama K., Crepineau F., Chaput N., Flament C., et al. IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules. J Immunol 2004, 172:5957-5966.
14. Zitvogel L., Terme M., Borg C., Trinchieri G. Dendritic cell-NK cell cross-talk: regulation and physiopathology. Curr Top Microbiol Immunol 2006, 298:157-174.
15. Fernandez N.C., Flament C., Crepineau F., Angevin E., Vivier E., Zitvogel L. Dendritic cells (DC) promote natural killer (NK) cell functions: dynamics of the human DC/NK cell cross talk. Eur Cytokine Netw 2002, 13:17-27.
16. Horowitz A., Behrens R.H., Okell L., Fooks A.R., Riley E.M. NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination. J Immunol 2010, 185:2808-2818.
17. He X.S., Draghi M., Mahmood K., Holmes T.H., Kemble G.W., Dekker C.L., et al. T cell-dependent production of IFN-gamma by NK cells in response to influenza A virus. J Clin Invest 2004, 114:1812-1819.
18. Stickl H., Hochstein-Mintzel V., Mayr A., Huber H.C., Schafer H., Holzner A. MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA). Dtsch Med Wochenschr 1974, 99:2386-2392. (author's transl).
19. Drexler I., Staib C., Sutter G. Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential. Curr Opin Biotechnol 2004, 15:506-512.
20. Brandler S., Lepelley A., Desdouits M., Guivel-Benhassine F., Ceccaldi P.E., Levy Y., et al. Preclinical studies of a modified vaccinia virus Ankara-based HIV candidate vaccine: antigen presentation and antiviral effect. J Virol 2010, 84:5314-5328.
21. Alter G., Malenfant J.M., Altfeld M. CD107a as a functional marker for the identification of natural killer cell activity. J Immunol Methods 2004, 294:15-22.
22. Chahroudi A., Garber D.A., Reeves P., Liu L., Kalman D., Feinberg M.B. Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus. J Virol 2006, 80:8469-8481.
23. Zhang X., Cassis-Ghavami F., Eller M., Currier J., Slike B.M., Chen X., et al. Direct comparison of antigen production and induction of apoptosis by canarypox virus- and modified vaccinia virus ankara-human immunodeficiency virus vaccine vectors. J Virol 2007, 81:7022-7033.
24. Nguyen K.B., Salazar-Mather T.P., Dalod M.Y., Van Deusen J.B., Wei X.Q., Liew F.Y., et al. Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. J Immunol 2002, 169:4279-4287.
25. Ferlazzo G., Pack M., Thomas D., Paludan C., Schmid D., Strowig T., et al. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc Natl Acad Sci USA 2004, 101:16606-16611.
26. Caligiuri M.A. Human natural killer cells. Blood 2008, 112:461-469.
27. Moreno-Nieves U.Y., Didier C., Lévy Y., Barré-Sinoussi F., Scott-Algara D. NK cells are primed by ANRS MVAHIV-infected DCs, via a mechanism involving NKG2D and membrane-bound IL-15, to efficiently control HIV-1 infection in CD4+ T cells. Eur J Immunol 2014, (AHVN) AHVN, (in press). 10.1002/eji.201344149.
28. Matusali G., Potesta M., Santoni A., Cerboni C., Doria M. The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR. J Virol 2012, 86:4496-4504.
29. Nolting A., Dugast A.S., Rihn S., Luteijn R., Carrington M.F., Kane K., et al. MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction. Virology 2010, 406:12-20.
30. Pham T.N., Richard J., Gerard F.C., Power C., Cohen E.A. Modulation of NKG2D-mediated cytotoxic functions of natural killer cells by viral protein R from HIV-1 primary isolates. J Virol 2011, 85:12254-12261.
31. Cerboni C., Neri F., Casartelli N., Zingoni A., Cosman D., Rossi P., et al. Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity. J Gen Virol 2007, 88:242-250.
32. Carrington M., Martin M.P., van Bergen J. KIR-HLA intercourse in HIV disease. Trends Microbiol 2008, 16:620-627.
33. Alter G., Martin M.P., Teigen N., Carr W.H., Suscovich T.J., Schneidewind A., et al. Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J Exp Med 2007, 204:3027-3036.
34. Merino A., Malhotra R., Morton M., Mulenga J., Allen S., Hunter E., et al. Impact of a functional KIR2DS4 allele on heterosexual HIV-1 transmission among discordant Zambian couples. J Infect Dis 2011, 203:487-495.
35. Fang M., Lanier L.L., Sigal L.J. A role for NKG2D in NK cell-mediated resistance to poxvirus disease. PLoS Pathog 2008, 4:e30.
36. Narni-Mancinelli E., Jaeger B.N., Bernat C., Fenis A., Kung S., De Gassart A., et al. Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science 2012, 335:344-348.
37. Nabekura T., Kanaya M., Shibuya A., Fu G., Gascoigne N.R., Lanier L.L. Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection. Immunity 2014, 40(2):225-234.
38. Cooper M.A., Yokoyama W.M. Memory-like responses of natural killer cells. Immunol Rev 2010, 235:297-305.
39. Paust S., Senman B., von Andrian U.H. Adaptive immune responses mediated by natural killer cells. Immunol Rev 2010, 235:286-296.
40. Sun J.C., Beilke J.N., Lanier L.L. Adaptive immune features of natural killer cells. Nature 2009, 457:557-561.