4-Hydroxyisoleucine improves insulin resistance by promoting mitochondrial biogenesis and act through AMPK and Akt dependent pathway

Fitoterapia

Volumn 99, Issue , 2014, Pages 307-317

  Rawat, Arun Kumar ^a   Korthikunta, Venkateswarlu ^a   Gautam, Sudeep ^a   Pal, Savita ^a   Tadigoppula, Narender ^a   Tamrakar, Akhilesh Kumar ^a   Srivastava, Arvind Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

4 Hydroxyisoleucine; Glucose tolerance; Insulin resistance; L6 myotube; Mitochondrial biogenesis

Indexed keywords

4 HYDROXYISOLEUCINE; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 2; CARNITINE PALMITOYLTRANSFERASE I; FENOFIBRATE; FRUCTOSE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PROTEIN KINASE B; STREPTOZOCIN; UNCLASSIFIED DRUG; 4-HYDROXYISOLEUCINE; GLUCOSE BLOOD LEVEL; ISOLEUCINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BIOGENESIS; BLOOD SAMPLING; CONTROLLED STUDY; DIETARY INTAKE; DRUG EFFICACY; ENERGY METABOLISM; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID ANALYSIS; LIPID BLOOD LEVEL; LIVER; MALE; MITOCHONDRION; MUSCLE TISSUE; MYOTUBE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORAL GLUCOSE TOLERANCE TEST; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION; REGULATOR GENE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; SPRAGUE DAWLEY RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOOD GLUCOSE; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION REGULATION; INSULIN RESISTANCE; ISOLEUCINE; MALE; MITOCHONDRIA; MUSCLE FIBERS, SKELETAL; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84908505693     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2014.10.006     Document Type: Article

References (39)

1. K.G.M.M. Alberti, and P. Zimmet Definition, diagnosis and classification of diabetes mellitus and its complications Part 1: diagnosis and classification of diabetes mellitus Provisional report of a WHO consultation, Diabetic medicine. 15 1998 539 553
2. J. Tuomilehto, J. Lindström, J.G. Eriksson, T.T. Valle, H. Hämäläinen, and P. Ilanne-Parikka Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance N Engl J Med 344 2001 1343 1350
3. D.E. Kelley, M. Mokan, J.-A. Simoneau, and L. Mandarino Interaction between glucose and free fatty acid metabolism in human skeletal muscle J Clin Investig 92 1993 91
4. R.M. Bezerra, M. Ueno, M.S. Silva, D.Q. Tavares, C.R. Carvalho, and M.J. Saad A high-fructose diet induces insulin resistance but not blood pressure changes in normotensive rats Braz J Med Biol Res 34 2001 1155 1160
5. I. Zavaroni, S. Sander, S. Scott, and G.M. Reaven Effect of fructose feeding on insulin secretion and insulin action in the rat Metabolism 29 1980 970 973
6. A. Stark, B. Timar, and Z. Madar Adaption of Sprague Dawley rats to long-term feeding of high fat of high fructose diets Eur J Nutr 39 2000 229 234
7. S. Smyth, and A. Heron Diabetes and obesity: the twin epidemics Nat Med 12 2006 75 80
8. F.E. Koehn, and G.T. Carter The evolving role of natural products in drug discovery Nat Rev Drug Discov 4 2005 206 220
9. C.J. Bailey, and C. Day Traditional plant medicines as treatments for diabetes Diabetes Care 12 1989 553 564
10. S. Ocvirk, M. Kistler, S. Khan, S.H. Talukder, and H. Hauner Traditional medicinal plants used for the treatment of diabetes in rural and urban areas of Dhaka, Bangladesh - an ethnobotanical survey J Ethnobiol Ethnomed 9 2013 43
11. R. Sharma, and T. Raghuram Hypoglycaemic effect of fenugreek seeds in non-insulin dependent diabetic subjects Nutr Res 10 1990 731 739
12. N.H.A. El-Soud, M. Khalil, J. Hussein, F. Oraby, and A.H. Farrag Antidiabetic effects of fenugreek alkaliod extract in streptozotocin induced hyperglycemic rats J Appl Sci Res 3 2007 1073 1083
13. T. Zia, S.N. Hasnain, and S. Hasan Evaluation of the oral hypoglycaemic effect of Trigonella foenum-graecum L. (methi) in normal mice J Ethnopharmacol 75 2001 191 195
14. M. AlHabori, and A. Raman Antidiabetic and hypocholesterolaemic effects of fenugreek Phytother Res 12 1998 233 242
15. Y. Sauvaire, P. Petit, C. Broca, M. Manteghetti, Y. Baissac, and J. Fernandez-Alvarez 4-Hydroxyisoleucine: a novel amino acid potentiator of insulin secretion Diabetes 47 1998 206 210
16. C. Broca, R. Gross, P. Petit, Y. Sauvaire, M. Manteghetti, and M. Tournier 4-Hydroxyisoleucine: experimental evidence of its insulinotropic and antidiabetic properties Am J Physiol 277 1999 E617 E623
17. N. Jaiswal, C.K. Maurya, K. Venkateswarlu, P. Sukanya, A.K. Srivastava, and T. Narender 4-Hydroxyisoleucine stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells via phosphatidylinositol-3-kinase-dependent pathway Eur J Nutr 51 2012 893 898
18. L. Fowden, H.M. Pratt, and A. Smith 4-Hydroxyisoleucine from seed of Trigonella foenum-graecum Phytochemistry 12 1973 1707 1711
19. N.W. Alcock, D.H. Crout, M.V. Gregorio, E. Lee, G. Pike, and C.J. Samuel Stereochemistry of the 4-hydroxyisoleucine from Trigonella foenum-graecum Phytochemistry 28 1989 1835 1841
20. R.M.N. Bezerra, M. Ueno, M.S. Silva, D.Q. Tavares, C.R.O. Carvalho, and M.J.A. Saad A high fructose diet affects the early steps of insulin action in muscle and liver of rats J Nutr 130 2000 1531 1535
21. K. Sawada, K. Kawabata, T. Yamashita, K. Kawasaki, N. Yamamoto, and H. Ashida Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells Lipids Health Dis 11 2012 36 44
22. G. Naresh, N. Jaiswal, P. Sukanya, A.K. Srivastava, A.K. Tamrakar, and T. Narender Glucose uptake stimulatory effect of 4-hydroxypipecolic acid by increased GLUT 4 translocation in skeletal muscle cells Bioorg Med Chem Lett 22 2012 5648 5651
23. S. Kwon, Y.J. Kim, and M.K. Kim Effect of fructose or sucrose feeding with different levels on oral glucose tolerance test in normal and type 2 diabetic rats Nutr Res Pract 2 2008 252 258
24. S. Weksler-Zangen, I. Raz, S. Lenzen, A. Jörns, S. Ehrenfeld, and G. Amir Impaired glucose-stimulated insulin secretion is coupled with exocrine pancreatic lesions in the Cohen diabetic rat Diabetes 57 2008 279 287
25. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(- delta delta C(T)) method Methods 25 2001 402 408
26. Q.-X. Li, Z.-Y. Xiong, B.-P. Hu, H.-F. Zhang, W.-Y. Gou, and H.-C. Wang Aging-associated insulin resistance predisposes to hypertension and its reversal by exercise: the role of vascular vasorelaxation to insulin Basic Res Cardiol 104 2009 269 284
27. Z. Wu, P. Puigserver, U. Andersson, C. Zhang, G. Adelmant, and V. Mootha Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1 Cell 98 1999 115 124
28. L.H. Storlien, N.D. Oakes, D.A. Pan, M. Kusunoki, and A.B. Jenkins Syndromes of insulin resistance in the rat: inducement by diet and amelioration with benfluorex Diabetes 42 1993 457 462
29. M.-K. Lee, P.D. Miles, M. Khoursheed, K.-M. Gao, A. Moossa, and J.M. Olefsky Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat Diabetes 43 1994 1435 1439
30. C. Broca, V. Breil, C. Cruciani-Guglielmacci, M. Manteghetti, C. Rouault, and M. Derouet Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat Am J Physiol Endocrinol Metab 287 2004 E463 E471
31. D. Carling The AMP-activated protein kinase cascade - a unifying system for energy control Trends Biochem Sci 29 2004 18 24
32. L. Ji, X. Zhang, W. Liu, Q. Huang, W. Yang, and F. Fu AMPK-regulated and Akt-dependent enhancement of glucose uptake is essential in ischemic preconditioning-alleviated reperfusion injury PLoS One 8 2013 e69910
33. L. Chen, F. Wang, X. Sun, J. Zhou, L. Gao, and Y. Jiao Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium Exp Mol Med 42 2010 205 215
34. J.S. Fisher, J. Gao, D.-H. Han, J.O. Holloszy, and L.A. Nolte Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin American Journal of Physiology-Endocrinology And Metabolism 282 2002 E18 E23
35. S.N. Jakobsen, D.G. Hardie, N. Morrice, and H.E. Tornqvist 5′-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside J Biol Chem 276 2001 46912 46916
36. S. Jäger, C. Handschin, J.S. Pierre, and B.M. Spiegelman AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α Proc Natl Acad Sci 104 2007 12017 12022
37. A. Santel, and M.T. Fuller Control of mitochondrial morphology by a human mitofusin J Cell Sci 114 2001 867 874
38. K. Lee, J. Kerner, and C.L. Hoppel Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex J Biol Chem 286 2011 25655 25662
39. W. Winder, B. Holmes, D. Rubink, E. Jensen, M. Chen, and J. Holloszy Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle J Appl Physiol 88 2000 2219 2226