Role of mas receptor antagonist (A779) on pressure diuresis and natriuresis and renal blood flow in the absence of angiotensin II receptors type 1 and 2 in female and male rats

Journal of Physiology and Pharmacology

Volumn 65, Issue 5, 2014, Pages 633-639

  Mansoori, A ^a,b   Oryan, S ^b   Nematbakhsh, Mehdi ^a,c  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b KHARAZMI UNIVERSITY   (Iran)

^c IsfahanMN Institute of Basic Applied Sciences Research   (Iran)

Author keywords

Angiotensin 1 7; Angiotensin converting enzyme; Angiotensin II receptors; Mas receptor; Renal blood flow; Renin; Sodium excretion; Urine output

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4, 5, 6, 7 TETRAHYDRO 1H IMIDAZO [4, 5 C] PYRIDINE 6 CARBOXYLIC ACID; ALDOSTERONE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN [1-7] [7 DEXTRO ALANINE]; BRADYKININ; DIPEPTIDYL CARBOXYPEPTIDASE; LOSARTAN; RENIN; UNCLASSIFIED DRUG; VASOPRESSIN V2 RECEPTOR; 1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 7-ALA-ANGIOTENSIN (1-7); ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN II; G PROTEIN COUPLED RECEPTOR; IMIDAZOLE DERIVATIVE; ONCOPROTEIN; PEPTIDE FRAGMENT; PROTO-ONCOGENE PROTEINS C-MAS-1; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIURESIS; ENZYME ACTIVITY; FEMALE; KIDNEY BLOOD FLOW; KIDNEY PERFUSION; KIDNEY VASCULAR RESISTANCE; MALE; NATRIURESIS; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; RENAL SYSTEM PARAMETERS; SODIUM EXCRETION; URINARY TRACT FUNCTION; URINE FLOW RATE; URINE VOLUME; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; KIDNEY; KIDNEY CIRCULATION; METABOLISM; PHYSIOLOGY; PRESSURE; SEX DIFFERENCE; VASCULAR RESISTANCE; WISTAR RAT;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN II TYPE 2 RECEPTOR BLOCKERS; ANIMALS; DIURESIS; FEMALE; IMIDAZOLES; KIDNEY; LOSARTAN; MALE; NATRIURESIS; PEPTIDE FRAGMENTS; PRESSURE; PROTO-ONCOGENE PROTEINS; PYRIDINES; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, G-PROTEIN-COUPLED; RENAL CIRCULATION; SEX FACTORS; VASCULAR RESISTANCE;

EID: 84908464918     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article

References (68)

1. Oparil S, Miller AP. Gender and blood pressure. J Clin Hypertens 2005; 7: 300-309.
2. Silbiger SR, Neugarten J. The role of gender in the progression of renal disease. Advances in renal replacement therapy. Adv Ren Replace Ther 2003; 10: 3-14.
3. Sullivan JC. Sex and the renin-angiotensin system: inequality between the sexes in response to RAS stimulation and inhibition. Am J Physiol Regul Integr Comp Physiol 2008; 294: R1220-R1226.
4. Tharaux PL, Chatziantoniou C, Fakhouri F, Dussaule JC. Angiotensin II activates collagen I gene through a mechanism involving the MAP/ER kinase pathway. Hypertension 2000; 36: 330-336.
5. Jawien J, Toton-Zuranska J, Gajda M, et al. Angiotensin- (1-7) receptor Mas agonist ameliorates progress of atherosclerosis in apoE-knockout mice. J Physiol Pharmacol 2012; 63: 77-85.
6. Schneider MP, Wach PF, Durley MK, Pollock JS, Pollock DM. Sex differences in acute ANG II-mediated hemodynamic responses in mice. Am J Physiol Regul Integr Comp Physiol 2010; 299: R899-R906.
7. Sampson AK, Moritz KM, Jones ES, Flower RL, Widdop RE, Denton KM. Enhanced angiotensin II type 2 receptor mechanisms mediate decreases in arterial pressure attributable to chronic low-dose angiotensin II in female rats. Hypertension 2008; 52: 666-671.
8. Dilauro M, Burns KD. Angiotensin-(1-7) and its effects in the kidney. ScientificWorldJournal 2009; 9: 522-535.
9. Bosnyak S, Jones ES, Christopoulos A, Aguilar MI, Thomas WG, Widdop RE. Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. Clin Sci (London) 2011; 121: 297-303.
10. Olszanecki R, Suski M, Gebska A, et al. The influence of angiotensin-(1-7) peptidomimetic (AVE 0991) and nebivolol on angiotensin i metabolism in aorta of apoE-knockout mice. J Physiol Pharmacol 2013; 64: 317-320.
11. Dahl T, Hultstrom M, Iversen B, Helle F. Adenosine sensitization after angiotensin II stimulation in afferent arterioles from normal rats does not occur during twokidney, one-clip hypertension. Acta Physiol (Oxford) 2011; 201: 289-294.
12. Lyngso C, Erikstrup N, Hansen JL. Functional interactions between 7TM receptors in the renin-angiotensin systemdimerization or crosstalk? Mol Cell Endocrinol 2009; 302: 203-212.
13. Zhuo JL, Li XC. New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II. Peptides 2011: 32: 1551-1565.
14. Campbell DJ. The renin-angiotensin and the kallikrein-kinin systems. Int J Biochem Cell Biol 2003; 35: 784-791.
15. Fernandes L, Fortes ZB, Nigro D, Tostes RC, Santos R., Catelli de Carvalho MH. Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneouslyhypertensive rats studied in vivo. Hypertension 2001; 37: 703-709.
16. Burgelova M, Kramer HJ, Teplan V, Thumova M, Cervenka L. Effects of angiotensin-(1-7) blockade on renal function in rats with enhanced intrarenal Ang II activity. Kidney Int 2005; 67: 1453-1461.
17. Castro CH, Santos R., Ferreira AJ, Bader M, Alenina N, Almeida AP. Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. Hypertension 2005; 46: 937-942.
18. Velkoska E, Dean R, Griggs K, Burchill L, Burrell L. Angiotensin-(1-7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy. Clin Sci (London) 2011; 120: 335-345.
19. Khraibi AA, Liang M, Berndt TJ. Role of gender on renal interstitial hydrostatic pressure and sodium excretion in rats. Am J Hypertens 2001; 14: 893-896.
20. Handa RK, Ferrario CM, Strandhoy JW. Renal actions of angiotensin-(1-7): in vivo and in vitro studies. Am J Physiol 1996; 270: F141-F147.
21. Andreatta van Leyen S, Romero MF, Khosla MC, Douglas JG. Modulation of phospholipase A2 activity and sodium transport by angiotensin-(l-7). Kidney Int 1993; 44: 932-936.
22. Sampson AK, Moritz KM, Denton KM. Postnatal ontogeny of angiotensin receptors and ACE2 in male and female rats. Gend Med 2012: 9: 21-32.
23. Zhuo J, Song K, Abdelrahman A, Mendelsohn FA. Blockade by intravenous losartan of AT1 angiotensin II receptors in rat brain, kidney and adrenals demonstrated by in vitro autoradiography. Clin Exp Pharmacol Physiol 1994; 21: 557-567.
24. Santos R., Haibara AS, Campagnole-Santos MJ, et al. Scientific contributions-characterization of a new selective antagonist for angiotensin-(1-7), D-Pro7-angiotensin-(1-7). Hypertension 2003; 41: 737-743.
25. Moon JY. ACE2 and angiotensin-(1-7) in hypertensive renal disease. Electrolyte Blood Press 2011; 9: 41-44.
26. Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, et al. A novel angiotensin-converting enzymerelated carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000; 87: e1-e9.
27. Ishiyama Y, Gallagher PE, Averill DB, Tallant EA, Brosnihan KB, Ferrario CM. Upregulation of angiotensinconverting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors. Hypertension 2004; 43: 970-976.
28. Li JH, Zhu HJ, Huang XR, Lai KN, Johnson RJ, Lan HY. Smad7 inhibits fibrotic effect of TGF-b on renal tubular epithelial cells by blocking Smad2 activation. J Am Soc Nephrol 2002; 13: 1464-1472.
29. Stegbauer J, Vonend O, Oberhauser V, Rump LC. Effects of angiotensin-(1-7) and other bioactive components of the renin-angiotensin system on vascular resistance and noradrenaline release in rat kidney. J Hypertens 2003; 21: 1391-1399.
30. Iyer SN, Ferrario CM, Chappell MC. Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system. Hypertension 1998; 31: 356-361.
31. Fan X, Wang Y, Sun K, et al. Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of captopril in women. Clin Pharmacol Ther 2007; 82: 187-196.
32. Ruggenenti P, Perna A, Zoccali C, et al. Chronic proteinuric nephropathies. II. Outcomes and response to treatment in a prospective cohort of 352 patients: differences between women and men in relation to the ACE gene polymorphism. J Am Soc Nephrol 2000; 11: 88-96.
33. Vickers C, Hales P, Kaushik V, et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 2002; 277: 14838-14843.
34. Igase M, Strawn WB, Gallagher PE, Geary RL, Ferrario CM. Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2005; 289: H1013-H1019.
35. Ferrario CM. Angiotensin-converting enzyme 2 and angiotensin-(1-7) an evolving story in cardiovascular regulation. Hypertension 2006; 47: 515-521.
36. Souza AP, Sobrinho DB, Almeida JF, et al. Angiotensin II type 1 receptor blockade restores angiotensin-(1-7)-induced coronary vasodilation in hypertrophic rat hearts. Clin Sci (London) 2013; 125: 449-459.
37. Ueda S, Masumori-Maemoto S, Wada A, Ishii M, Brosnihan KB, Umemura S. Angiotensin (1-7) potentiates bradykinininduced vasodilatation in man. J Hypertens 2001; 19: 2001-2009.
38. Tom B, de Vries R, Saxena PR, Danser AJ. Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C-and N-domain blockade. Hypertension 2001; 38: 95-99.
39. Prada JA, Ferreira AJ, Katovich MJ, et al. Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension 2008; 51: 1312-1317.
40. Vanhoutte PM. Endothelium and control of vascular function. State of the art lecture. Hypertension 1989; 13: 658-667.
41. Mattson DL, Cowley A. Kinin actions on renal papillary blood flow and sodium excretion. Hypertension 1993; 21: 961-965.
42. Lara L, De Carvalho T, Leao-Ferreira LR, Lopes AG, Caruso-Neves C. Modulation of the (Na(+)+K+) ATPase activity by angiotensin-(1-7) in MDCK cells. Regul Pept 2005; 129: 221-226.
43. Hall JE, Brands MW, Henegar JR. Angiotensin II and longterm arterial pressure regulation: the overriding dominance of the kidney. J Am Soc Nephrol 1999; 10 (Suppl. 12): S258-S265.
44. Simoes e Silva AC, Bello AP, Baracho NC, Khosla MC, Santos RA. Diuresis and natriuresis produced by long term administration of a selective angiotensin-(1-7) antagonist in normotensive and hypertensive rats. Regul Pept 1998; 74: 177-184.
45. Vallon V, Richter K, Heyne N, Osswald H. Effect of intratubular application of angiotensin 1-7 on nephron function. Kidney Blood Press Res 1997; 20: 233-239.
46. Simoes-e-Silva A, Baracho N, Passaglio K, Santos R. Renal actions of angiotensin-(1-7). Braz J Med Biol Res 1997; 30: 503-513.
47. Chappell MC, Diz DI, Yunis C, Ferrario CM. Differential actions of angiotensin-(1-7) in the kidney. Kidney Int 1998; 54: S3-S6.
48. Magaldi AJ, Cesar KR, de Araujo M, Simoes e Silva AC, Santos RA. Angiotensin-(1-7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors. Pflugers Archiv 2003; 447: 223-230.
49. Souza Dos Santos RA, Passaglio KT, Pesquero JB, Bader M, Simoes e Silva AC. Interactions between angiotensin-(1-7), kinins, and angiotensin II in kidney and blood vessels. Hypertension 2001; 38: 660-664.
50. Garcia NH, Garvin JL. Angiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubule. J Am Soc Nephrol 1994; 5: 1133-1138.
51. Ferreira AJ, Pinheiro SV, Castro CH, et al. Renal function in transgenic rats expressing an angiotensin-(1-7)-producing fusion protein. Regul Pept 2006; 137: 128-133.
52. Joyner J, Neves LA, Stovall K, Ferrario CM, Brosnihan KB. Angiotensin-(1-7) serves as an aquaretic by increasing water intake and diuresis in association with downregulation of aquaporin-1 during pregnancy in rats. Am J Physiol Regul Integr Comp Physiol 2008; 294: R1073-R1080.
53. Lopez Ordieres MG, Gironacci M, Rodriguez de Lores Arnaiz G, Pena C. Effect of angiotensin-(1-7) on ATPase activities in several tissues. Regul Pept 1998; 77: 135-139.
54. Oudit GY, Kassiri Z, Patel MP, et al. Angiotensin IImediated oxidative stress and inflammation mediate the agedependent cardiomyopathy in ACE2 null mice. Cardiovasc Res 2007; 75: 29-39.
55. Muthalif MM, Benter IF, Uddin MR, Harper JL, Malik KU. Signal transduction mechanisms involved in angiotensin-(1- 7)-stimulated arachidonic acid release and prostanoid synthesis in rabbit aortic smooth muscle cells. J Pharmacol Exp Ther 1998; 284: 388-398.
56. Santos R., Simoes e Silva AC, Magaldi AJ, et al. Evidence for a physiological role of angiotensin-(1-7) in the control of hydroelectrolyte balance. Hypertension 1996; 27: 875-884.
57. Safari T, Nematbakhsh M, Hilliard LM, Evans RG, Denton KM. Sex differences in the renal vascular response to angiotensin II involves the Mas receptor. Acta Physiol (Oxf) 2012; 206: 150-156.
58. Su Z, Zimpelmann J, Burns K. Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells. Kidney Int 2006; 69: 2212-2218.
59. Chappell MC, Modrall JG, Diz DI, Ferrario CM. Novel aspects of the renal renin-angiotensin system: angiotensin- (1-7), ACE2 and blood pressure regulation. Contrib Nephrol 2004; 143: 77-89.
60. AbdAlla S, Lother H, Abdel-tawab AM, Quitterer U. The angiotensin II AT2 receptor is an AT1 receptor antagonist. J Biol Chem 2001; 276: 39721-39726.
61. AbdAlla S, Lother H, Quitterer U. AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. Nature 2000; 407: 94-98.
62. Kostenis E, Milligan G, Christopoulos A, et al. G-proteincoupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor. Circulation 2005; 111: 1806-1813.
63. Canals M, Jenkins L, Kellett E, Milligan G. Up-regulation of the angiotensin II type 1 receptor by the MAS protooncogene is due to constitutive activation of Gq/G11 by MAS. J Biol Chem 2006; 281: 16757-16767.
64. Porrello ER, Delbridge L, Thomas WG. The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor. Front Biosci (Landmark). 2008; 14: 958-972.
65. van der Wouden EA, Ochodnicky P, van Dokkum RP, et al. The role of angiotensin (1-7) in renal vasculature of the rat. J Hypertens 2006; 24: 1971-1978.
66. Kobori H, Nangaku M, Navar LG, Nishiyama A. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 2007; 59: 251-287.
67. Kimbrough H, Vaughan E, Carey RM, Ayers C. Effect of intrarenal angiotensin II blockade on renal function in conscious dogs. Circ Res 1977; 40: 174-178.
68. Cervenka L, Wang CT, Navar LG. Effects of acute AT1 receptor blockade by candesartan on arterial pressure and renal function in rats. Am J Physiol 1998; 274: F940-F945.