Indazole-type alkaloids from nigella sativa seeds exhibit antihyperglycemic effects via AMPK activation in vitro

Journal of Natural Products

Volumn 77, Issue 10, 2014, Pages 2316-2320

  Yuan, Tao ^a,b   Nahar, Pragati ^b   Sharma, Meenakshi ^b   Liu, Ke ^c   Slitt, Angela ^b   Aisa, H A ^a   Seeram, Navindra P ^b  

^a XINJIANG TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY   (China)

^b UNIVERSITY OF RHODE ISLAND   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 O (BETA GLUCOPYRANOSYL) 4 O METHYLNIGELLIDINE; ALKALOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDAZOLE DERIVATIVE; NIGELANOID; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT;

ANTIDIABETIC ACTIVITY; ARTICLE; BLACK CUMIN; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; GLUCOSE INTAKE; HUMAN; HUMAN CELL; LIVER CELL; PLANT SEED; PROTON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CHEMISTRY; HEPG2 CELL LINE; ISOLATION AND PURIFICATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE;

NIGELLA SATIVA;

ALKALOIDS; AMP-ACTIVATED PROTEIN KINASES; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYPOGLYCEMIC AGENTS; INDAZOLES; MOLECULAR STRUCTURE; NIGELLA SATIVA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SEEDS;

EID: 84908439553     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np500398m     Document Type: Article

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