메뉴 건너뛰기




Volumn 58, Issue 11, 2014, Pages 6986-6989

In vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins

Author keywords

[No Author keywords available]

Indexed keywords

CEFIXIME; CEFPODOXIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; ERYTHROMYCIN; GAMMA GLUTAMYLTRANSFERASE; PENICILLIN DERIVATIVE; TETRACYCLINE; ANTIINFECTIVE AGENT; BETA LACTAMASE; FIMBRIA PROTEIN; PENICILLIN BINDING PROTEIN; PILQ PROTEIN, BACTERIA;

EID: 84908430626     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.03082-14     Document Type: Article
Times cited : (16)

References (35)
  • 2
    • 33749512799 scopus 로고    scopus 로고
    • Antibiotic resistance in Neisseria gonorrhoeae is diminishing available treatment options for gonorrhea: Some possible remedies
    • Tapsall J. 2006. Antibiotic resistance in Neisseria gonorrhoeae is diminishing available treatment options for gonorrhea: some possible remedies. Expert Rev. Anti Infect. Ther. 4:619-628. http://dx.doi.org/10.1586/14787210.4.4.619.
    • (2006) Expert Rev. Anti Infect. Ther. , vol.4 , pp. 619-628
    • Tapsall, J.1
  • 3
    • 70350627375 scopus 로고    scopus 로고
    • Meeting the public health challenge of multidrug- and extensively drug-resistant Neisseria gonorrhoeae
    • Tapsall JW, Ndowa F, Lewis DA, Unemo M. 2009. Meeting the public health challenge of multidrug- and extensively drug-resistant Neisseria gonorrhoeae. Expert Rev. Anti Infect. Ther. 7:821-834. http://dx.doi.org/10.1586/eri.09.63.
    • (2009) Expert Rev. Anti Infect. Ther. , vol.7 , pp. 821-834
    • Tapsall, J.W.1    Ndowa, F.2    Lewis, D.A.3    Unemo, M.4
  • 4
    • 67650488213 scopus 로고    scopus 로고
    • Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoeae verified by molecular microbiological methods
    • Tapsall J, Read P, Carmody C, Bourne C, Ray S, Limnios A, Sloots T, Wiley J. 2009. Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoeae verified by molecular microbiological methods. J. Med. Microbiol. 58:683-687. http://dx.doi.org/10.1099/jmm.0.007641-0.
    • (2009) J. Med. Microbiol. , vol.58 , pp. 683-687
    • Tapsall, J.1    Read, P.2    Carmody, C.3    Bourne, C.4    Ray, S.5    Limnios, A.6    Sloots, T.7    Wiley, J.8
  • 5
    • 79959189164 scopus 로고    scopus 로고
    • Is Neisseria gonorrhoeae initiating a future era of untreatable gonorrhea? Characterization of the first strain with high-level resistance to ceftriaxone
    • Ohnishi M, Goliparian D, Shimuta K, Saiki T, Hoshina S, Iwasaku K, Nakayama S, Kitikawa J, Unemo M. 2011. Is Neisseria gonorrhoeae initiating a future era of untreatable gonorrhea? Characterization of the first strain with high-level resistance to ceftriaxone. Antimicrob. Agents Chemother. 55:3538-3545. http://dx.doi.org/10.1128/AAC.00325-11.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 3538-3545
    • Ohnishi, M.1    Goliparian, D.2    Shimuta, K.3    Saiki, T.4    Hoshina, S.5    Iwasaku, K.6    Nakayama, S.7    Kitikawa, J.8    Unemo, M.9
  • 6
    • 84857146496 scopus 로고    scopus 로고
    • High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: Novel penA mosaic allele in a successful international clone causes treatment failure
    • Unemo M, Goliparian D, Nicholas RA, Ohnishi M, Gallay A, Sednaoui P. 2012. High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antmicrob. Agents Chemother. 56:1273-1280. http://dx.doi.org/10.1128/AAC.05760-11.
    • (2012) Antmicrob. Agents Chemother. , vol.56 , pp. 1273-1280
    • Unemo, M.1    Goliparian, D.2    Nicholas, R.A.3    Ohnishi, M.4    Gallay, A.5    Sednaoui, P.6
  • 7
    • 0025374274 scopus 로고
    • Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae
    • Brannigan JA, Tirodimos IA, Zhang Q-Y, Dowson CG, Spratt BG. 1990. Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae. Mol. Microbiol. 4:913-919. http://dx.doi.org/10.1111/j.1365-2958.1990.tb00664.x.
    • (1990) Mol. Microbiol. , vol.4 , pp. 913-919
    • Brannigan, J.A.1    Tirodimos, I.A.2    Zhang, Q.-Y.3    Dowson, C.G.4    Spratt, B.G.5
  • 8
    • 77952570638 scopus 로고    scopus 로고
    • Various penA mutations together with mtrR, porB, and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone
    • Lee S-G, Lee H, Jeong SH, Yong D, Chung GT, Lee YS, Chong Y, Lee K. 2010. Various penA mutations together with mtrR, porB, and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone. J. Antimicrob. Chemother. 65:669-675. http://dx.doi.org/10.1093/jac/dkp505.
    • (2010) J. Antimicrob. Chemother. , vol.65 , pp. 669-675
    • Lee, S.-G.1    Lee, H.2    Jeong, S.H.3    Yong, D.4    Chung, G.T.5    Lee, Y.S.6    Chong, Y.7    Lee, K.8
  • 9
    • 0030934312 scopus 로고    scopus 로고
    • Cloning and characterization of the ponA gene encoding penicillin-binding protein 1 from Neisseria gonorrhoeae and Neisseria meningitides
    • Ropp PA, Nicholas RA. 1997. Cloning and characterization of the ponA gene encoding penicillin-binding protein 1 from Neisseria gonorrhoeae and Neisseria meningitides. J. Bacteriol. 179:2783-2787.
    • (1997) J. Bacteriol. , vol.179 , pp. 2783-2787
    • Ropp, P.A.1    Nicholas, R.A.2
  • 10
    • 0036171501 scopus 로고    scopus 로고
    • Mutations in ponA, the gene encoding penicillin-binding protein 1 and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae
    • Ropp PA, Hu M, Olesky M, Nicholas RA. 2002. Mutations in ponA, the gene encoding penicillin-binding protein 1 and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 46:769-777. http://dx.doi.org/10.1128/AAC.46.3.769-777.2002.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 769-777
    • Ropp, P.A.1    Hu, M.2    Olesky, M.3    Nicholas, R.A.4
  • 11
    • 34347372857 scopus 로고    scopus 로고
    • Differential regulation of ponA and pilMNOPQ expression by the MtrR transcriptional regulatory protein in Neisseria gonorrhoeae
    • Folster JP, Dhulipala V, Nicholas RA, Shafer WM. 2007. Differential regulation of ponA and pilMNOPQ expression by the MtrR transcriptional regulatory protein in Neisseria gonorrhoeae. J. Bacteriol. 189:4569-4577. http://dx.doi.org/10.1128/JB.00286-07.
    • (2007) J. Bacteriol. , vol.189 , pp. 4569-4577
    • Folster, J.P.1    Dhulipala, V.2    Nicholas, R.A.3    Shafer, W.M.4
  • 12
    • 0028906903 scopus 로고
    • Resistance of Neisseria gonorrhoeae to hydrophobic agents is modulated by the mtrRCDE efflux system
    • Hagman KE, Pan W, Spratt BG, Balthazar JT, Judd RC, Shafer WM. 1995. Resistance of Neisseria gonorrhoeae to hydrophobic agents is modulated by the mtrRCDE efflux system. Microbiology 141:611-622. http://dx.doi.org/10.1099/13500872-141-3-611.
    • (1995) Microbiology , vol.141 , pp. 611-622
    • Hagman, K.E.1    Pan, W.2    Spratt, B.G.3    Balthazar, J.T.4    Judd, R.C.5    Shafer, W.M.6
  • 13
    • 0036785342 scopus 로고    scopus 로고
    • Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae
    • Veal WL, Nicholas RA, Shafer WM. 2002. Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. J. Bacteriol. 184:5619-5624. http://dx.doi.org/10.1128/JB.184.20.5619-5624.2002.
    • (2002) J. Bacteriol. , vol.184 , pp. 5619-5624
    • Veal, W.L.1    Nicholas, R.A.2    Shafer, W.M.3
  • 14
    • 0036719736 scopus 로고    scopus 로고
    • Identification and analysis of amino acid mutations in porin IB that mediate intermediate-level resistance to penicillin and tetracycline in Neisseria gonorrhoeae
    • Olesky M, Hobbs M, Nicholas RA. 2002. Identification and analysis of amino acid mutations in porin IB that mediate intermediate-level resistance to penicillin and tetracycline in Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 46:2811-2820. http://dx.doi.org/10.1128/AAC.46.9.2811-2820.2002.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 2811-2820
    • Olesky, M.1    Hobbs, M.2    Nicholas, R.A.3
  • 15
    • 0031753295 scopus 로고    scopus 로고
    • Gonococcal resistance to beta-lactams and tetracycline involves mutation in loop 3 of the porin encoded at the penB locus
    • Gill MJ, Simjee S, Al-Hatawi K, Robertson BD, Easmon CSF, Ison CA. 1998. Gonococcal resistance to beta-lactams and tetracycline involves mutation in loop 3 of the porin encoded at the penB locus. Antmicrob. Agents Chemother. 42:2799-2803.
    • (1998) Antmicrob. Agents Chemother. , vol.42 , pp. 2799-2803
    • Gill, M.J.1    Simjee, S.2    Al-Hatawi, K.3    Robertson, B.D.4    Easmon, C.S.F.5    Ison, C.A.6
  • 16
    • 0036895278 scopus 로고    scopus 로고
    • Mosaic-like structure of penicillin-binding protein 2 gene (penA) in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime
    • Ameyama S, Onodera S, Takahata M, Minami S, Maki N, Endo K, Goto H, Suzuki H, Oishi Y. 2002. Mosaic-like structure of penicillin-binding protein 2 gene (penA) in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime. Antimicrob. Agents Chemother. 46:3744-3749. http://dx.doi.org/10.1128/AAC.46.12.3744-3749.2002.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 3744-3749
    • Ameyama, S.1    Onodera, S.2    Takahata, M.3    Minami, S.4    Maki, N.5    Endo, K.6    Goto, H.7    Suzuki, H.8    Oishi, Y.9
  • 17
    • 34250186426 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime and ceftriaxone: Association with genetic polymorphisms in penA, mtrR, porBIb, and ponA
    • Lindberg R, Fredlund H, Nicholas RA, Unemo M. 2007. Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime and ceftriaxone: association with genetic polymorphisms in penA, mtrR, porBIb, and ponA. Antimicrob. Agents Chemother. 51:2117-2122. http://dx.doi.org/10.1128/AAC.01604-06.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 2117-2122
    • Lindberg, R.1    Fredlund, H.2    Nicholas, R.A.3    Unemo, M.4
  • 18
    • 19944429215 scopus 로고    scopus 로고
    • Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in central Japan
    • Ito M, Deguchi T, Mizutani KS, Yasuda M, Yokoi S, Ito S-I, Takahashi Y, Ishihara S, Kawamura Y, Ezaki T. 2005. Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in central Japan. Antimicrob. Agents Chemother. 49:137-143. http://dx.doi.org/10.1128/AAC.49.1.137-143.2005.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 137-143
    • Ito, M.1    Deguchi, T.2    Mizutani, K.S.3    Yasuda, M.4    Yokoi, S.5    Ito, S.-I.6    Takahashi, Y.7    Ishihara, S.8    Kawamura, Y.9    Ezaki, T.10
  • 19
    • 0026776971 scopus 로고
    • Role of interspecies transfer of chromosomal genes in the evolution of penicillin resistance in pathogenic and commensal Neisseria species
    • Spratt BG, Bowler LD, Zhang QY, Zhou J, Smith JM. 1992. Role of interspecies transfer of chromosomal genes in the evolution of penicillin resistance in pathogenic and commensal Neisseria species. J. Mol. Evol. 34:115-125.
    • (1992) J. Mol. Evol. , vol.34 , pp. 115-125
    • Spratt, B.G.1    Bowler, L.D.2    Zhang, Q.Y.3    Zhou, J.4    Smith, J.M.5
  • 21
    • 0029883060 scopus 로고    scopus 로고
    • Cloning and characterization of the catalase gene of Neisseria gonorrhoeae: Use of the gonococcus as a host organism for recombinant DNA
    • Johnson SR, Steiner BM, Perkins GH. 1996. Cloning and characterization of the catalase gene of Neisseria gonorrhoeae: use of the gonococcus as a host organism for recombinant DNA. Infect. Immun. 64:2627-2634.
    • (1996) Infect. Immun. , vol.64 , pp. 2627-2634
    • Johnson, S.R.1    Steiner, B.M.2    Perkins, G.H.3
  • 23
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignments with Burrows-Wheeler transform
    • Li H, Durbin R. 2009. Fast and accurate short read alignments with Burrows-Wheeler transform. Bioinformatics 25:1754-1760. http://dx.doi.org/10.1093/bioinformatics/btp324.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 27
    • 77955801615 scopus 로고    scopus 로고
    • Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    • Goecks J, Nekrutenko A, Taylor J. 2010. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol. 11:R86. http://dx.doi.org/10.1186/gb-2010-11-8-r86.
    • (2010) Genome Biol , vol.11 , pp. R86
    • Goecks, J.1    Nekrutenko, A.2    Taylor, J.3
  • 28
    • 0030464460 scopus 로고    scopus 로고
    • SEAVIEW and PHYLO-Win: Two graphic tools for sequence alignment and molecular phylogeny
    • Galtier N, Gouy M, Carter C. 1996. SEAVIEW and PHYLO-Win: two graphic tools for sequence alignment and molecular phylogeny. Comput. Appl. Biosci. 12:543-548.
    • (1996) Comput. Appl. Biosci. , vol.12 , pp. 543-548
    • Galtier, N.1    Gouy, M.2    Carter, C.3
  • 29
    • 74549125386 scopus 로고    scopus 로고
    • SEAVIEW version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building
    • Gouy M, Guindon S, Gascuel O. 2010. SEAVIEW version 4: a multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Mol. Biol. Evol. 27:221-224. http://dx.doi.org/10.1093/molbev/msp259.
    • (2010) Mol. Biol. Evol. , vol.27 , pp. 221-224
    • Gouy, M.1    Guindon, S.2    Gascuel, O.3
  • 30
    • 84879012055 scopus 로고    scopus 로고
    • Identification of amino acids conferring high-level resistance to cephalosporins in the penA gene from Neisseria gonrrhoeae strain H041
    • Tomberg J, Unemo M, Ohnishi M, Davies C, Nicholas RA. 2013. Identification of amino acids conferring high-level resistance to cephalosporins in the penA gene from Neisseria gonrrhoeae strain H041. Antimicrob. Agents Chemother. 57:3029-3036. http://dx.doi.org/10.1128/AAC.00093-13.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , pp. 3029-3036
    • Tomberg, J.1    Unemo, M.2    Ohnishi, M.3    Davies, C.4    Nicholas, R.A.5
  • 31
    • 1642581491 scopus 로고    scopus 로고
    • A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds
    • Chen CJ, Tobiason DM, Thomas CE, Shafer WM, Seifert HS, Sparling PF. 2004. A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds. J. Bacteriol. 186:730-739. http://dx.doi.org/10.1128/JB.186.3.730-739.2004.
    • (2004) J. Bacteriol. , vol.186 , pp. 730-739
    • Chen, C.J.1    Tobiason, D.M.2    Thomas, C.E.3    Shafer, W.M.4    Seifert, H.S.5    Sparling, P.F.6
  • 32
    • 23844463837 scopus 로고    scopus 로고
    • The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability
    • Zhao S, Tobiason DM, Hu M, Seifert HS, Nicholas RA. 2005. The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability. Mol. Microbiol. 57:1238-1251. http://dx.doi.org/10.1111/j.1365-2958.2005.04752.x.
    • (2005) Mol. Microbiol. , vol.57 , pp. 1238-1251
    • Zhao, S.1    Tobiason, D.M.2    Hu, M.3    Seifert, H.S.4    Nicholas, R.A.5
  • 33
    • 0014335662 scopus 로고
    • Neisseria gonorrhoeae. II. Colonial variation and pathogenicity during 35 months in vitro
    • Kellogg DS, Jr, Cohen IR, Norins LC, Schroeter AL, Reising G. 1968. Neisseria gonorrhoeae. II. Colonial variation and pathogenicity during 35 months in vitro. J. Bacteriol. 96:596-605.
    • (1968) J. Bacteriol. , vol.96 , pp. 596-605
    • Kellogg, D.S.1    Cohen, I.R.2    Norins, L.C.3    Schroeter, A.L.4    Reising, G.5
  • 35
    • 34247850883 scopus 로고    scopus 로고
    • pilQ missense mutations have diverse effects on PilQ multimer formation, piliation and pilus function in Neisseria gonorrhoeae
    • Helm RA, Barnhart MM, Seifert HS. 2007. pilQ missense mutations have diverse effects on PilQ multimer formation, piliation and pilus function in Neisseria gonorrhoeae. J. Bacteriol. 189:3198-3207. http://dx.doi.org/10.1128/JB.01833-06.
    • (2007) J. Bacteriol. , vol.189 , pp. 3198-3207
    • Helm, R.A.1    Barnhart, M.M.2    Seifert, H.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.