Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro

Genetics in Medicine

Volumn 16, Issue 11, 2014, Pages 838-845

  Natesan, Senthilkumar A ^a   Bladon, Alex J ^a   Coskun, Serdar ^b   Qubbaj, Wafa ^b   Prates, Renata ^c   Munne, Santiago ^c   Coonen, Edith ^d,e   Dreesen, Joseph C F M ^d,e   Stevens, Servi J C ^d,e   Paulussen, Aimee D C ^d,e   Stock Myer, Sharyn E ^f   Wilton, Leeanda J ^f   Jaroudi, Souraya ^c   Wells, Dagan ^c   Brown, Anthony P C ^a   Handyside, Alan H ^a,g  

^a Illumina   (United Kingdom)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^c Reprogenetics LLC   (United States)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f MELBOURNE IVF   (Australia)

^g Bridge Centre   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA;

ARTICLE; BLASTOMA; CHROMOSOME 19; CHROMOSOME MAP; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; EMBRYO; FERTILIZATION IN VITRO; GENE AMPLIFICATION; GENE LOCUS; GENETIC DISORDER; GENOME ANALYSIS; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; INHERITANCE; KARYOTYPE; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; OOCYTE CLEAVAGE; PEUTZ JEGHERS SYNDROME; POLYMERASE CHAIN REACTION SYSTEM; PREIMPLANTATION EMBRYO; RETROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; BLASTOCYST; CLINICAL TRIAL; COMPARATIVE STUDY; FEMALE; GENOTYPING TECHNIQUE; HUMAN GENOME; IN VITRO STUDY; KARYOTYPING; MALE; MULTICENTER STUDY; PARENT; PRENATAL DIAGNOSIS; PROCEDURES; REPRODUCIBILITY;

BLASTOCYST; CHROMOSOME MAPPING; FEMALE; GENOME, HUMAN; GENOTYPING TECHNIQUES; HUMANS; IN VITRO TECHNIQUES; KARYOTYPING; MALE; PARENTS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREIMPLANTATION DIAGNOSIS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES;

EID: 84908422368     PISSN: 10983600     EISSN: 15300366     Source Type: Journal    
DOI: 10.1038/gim.2014.45     Document Type: Article

References (16)

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