β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase

Molecular Carcinogenesis

Volumn 53, Issue 10, 2014, Pages 793-806

  Kim, Chulwon ^a   Cho, Somi K ^b   Kapoor, Shweta ^c   Kumar, Ansu ^c   Vali, Shireen ^c,d   Abbasi, Taher ^d   Kim, Sung Hoon ^a   Sethi, Gautam ^e   Ahn, Kwang Seok ^a  

^a Kyung Hee University   (South Korea)

^b Jeju National University   (South Korea)

^c Lam Research India Pvt Ltd   (India)

^d CELLWORKS GROUP INC   (United States)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Apoptosis; sHP 1; STAT3; Caryophyllene oxide

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; CARYOPHYLLENE OXIDE; IL6 PROTEIN, HUMAN; INTERLEUKIN 6; JAK2 PROTEIN, HUMAN; JANUS KINASE 2; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PTPN6 PROTEIN, HUMAN; SESQUITERPENE; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; DRUG EFFECT; DRUG SCREENING; ENZYME INDUCTION; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN PROCESSING; SHP-1; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION; Β-CARYOPHYLLENE OXIDE;

APOPTOSIS; SHP-1; STAT3; Β-CARYOPHYLLENE OXIDE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INDUCTION; GENE EXPRESSION; HUMANS; INTERLEUKIN-6; JANUS KINASE 2; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; SESQUITERPENES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR;

EID: 84908316861     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22035     Document Type: Article

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