Solid tumor-targeting theranostic polymer nanoparticle in nuclear medicinal Fields

Scientific World Journal

Volumn 2014, Issue , 2014, Pages

  Makino, Akira ^a   Kimura, Shunsaku ^b  

^a UNIVERSITY OF FUKUI   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COPOLYMER; MACROGOL; NANOPARTICLE; POLY(EPSILON CAPROLACTONE) B POLY(ETHYLENE GLYCOL); POLY(ETHYLENE GLYCOL) B POLY(LACTIC ACID); POLY(LAURYLMETHACRYLATE) B POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE]; POLY(METHYL METHACRYLATE CO METHACRYLOXYSUCCINIMIDE); POLY(SARCOSINE) B POLY(LACTIC ACID); POLY(TRIETHOXYSILYLPROPYLMETHACRYLATE) B POLY(POLYETHYLENE GLYCOL METHACRYLATE); POLYMER; POLY[7 (2 METHACRYLOYLOXYETHOXY) 4 METHYLCOUMARIN] B POLY(HYDROXYETHYLMETHACRYLATE) B POLY(ETHYLENE GLYCOL); RADIOISOTOPE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

ARTICLE; CROSS LINKING; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEM; MICELLE; PLASMA CLEARANCE; POSITRON EMISSION TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLID TUMOR; THERMOSTABILITY; ANIMAL; CHEMISTRY; HUMAN; NEOPLASMS; NUCLEAR MEDICINE; PATHOLOGY; PROCEDURES; SURFACE PROPERTY;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; HUMANS; NANOPARTICLES; NEOPLASMS; NUCLEAR MEDICINE; POLYMERS; RADIOISOTOPES; SURFACE PROPERTIES;

EID: 84908315941     PISSN: 23566140     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2014/424513     Document Type: Article

References (59)

1. Hao R., Xing R. J., Xu Z. C., Hou Y. L., Goo S., Sun S. H., Synthesis, functionalization, and biomedical applications of multifunctional magnetic nanoparticles. Advanced Materials 2010 22 25 2729 2742 10.1002/adma.201000260 2-s2.0-77955202927
2. Horcajada P., Gref R., Baati T., Allan P. K., Maurin G., Couvreur P., Férey G., Morris R. E., Serre C., Metal-organic frameworks in biomedicine. Chemical Reviews 2012 112 2 1232 1268 10.1021/cr200256v 2-s2.0-84856956939
3. Peer D., Karp J. M., Hong S., Farokhzad O. C., Margalit R., Langer R., Nanocarriers as an emerging platform for cancer therapy. Nature Nanotechnology 2007 2 12 751 760 10.1038/nnano.2007.387 2-s2.0-36849067019
4. Ferrari M., Cancer nanotechnology: opportunities and challenges. Nature Reviews Cancer 2005 5 3 161 171 10.1038/nrc1566 2-s2.0-14644439267
5. Jain R. K., Stylianopoulos T., Delivering nanomedicine to solid tumors. Nature Reviews Clinical Oncology 2010 7 11 653 664 10.1038/nrclinonc.2010.139 2-s2.0-78049452610
6. Jiao Z., Wang X., Chen Z., Advance of amphiphilic block copolymeric micelles as drug delivery. Asian Journal of Chemistry 2013 25 4 1765 1769 2-s2.0-84875152179
7. Elsabahy M., Wooley K. L., Design of polymeric nanoparticles for biomedical delivery applications. Chemical Society Reviews 2012 41 7 2545 2561 10.1039/c2cs15327k 2-s2.0-84858673601
8. Ge Z., Liu S., Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance. Chemical Society Reviews 2013 42 17 7289 7325 10.1039/c3cs60048c 2-s2.0-84881454232
9. Ganta S., Devalapally H., Shahiwala A., Amiji M., A review of stimuli-responsive nanocarriers for drug and gene delivery. Journal of Controlled Release 2008 126 3 187 204 10.1016/j.jconrel.2007.12.017 2-s2.0-39649120532
10. Park J. H., Lee S., Kim J.-H., Park K., Kim K., Kwon I. C., Polymeric nanomedicine for cancer therapy. Progress in Polymer Science 2008 33 1 113 137 10.1016/j.progpolymsci.2007.09.003 2-s2.0-37249068568
11. Fang J., Nakamura H., Maeda H., The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Advanced Drug Delivery Reviews 2011 63 3 136 151 10.1016/j.addr.2010.04.009 2-s2.0-79953054576
12. Iyer A. K., Khaled G., Fang J., Maeda H., Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discovery Today 2006 11 17-18 812 818 10.1016/j.drudis.2006.07.005 2-s2.0-33747762229
13. Maeda H., Wu J., Sawa T., Matsumura Y., Hori K., Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. Journal of Controlled Release 2000 65 1-2 271 284 10.1016/S0168-3659(99)00248-5 2-s2.0-0034000453
14. Brannon-Peppas L., Blanchette J. O., Nanoparticle and targeted systems for cancer therapy. Advanced Drug Delivery Reviews 2012 64 206 212 10.1016/j.addr.2012.09.033 2-s2.0-84870242534
15. Egusquiaguirre S. P., Igartua M., Hernández R. M., Pedraz J. L., Nanoparticle delivery systems for cancer therapy: advances in clinical and preclinical research. Clinical and Translational Oncology 2012 14 2 83 93 10.1007/s12094-012-0766-6 2-s2.0-84860471928
16. Tanisaka H., Kizaka-Kondoh S., Makino A., Tanaka S., Hiraoka M., Kimura S., Near-infrared fluorescent labeled peptosome for application to cancer imaging. Bioconjugate Chemistry 2008 19 1 109 117 10.1021/bc7001665 2-s2.0-38949131498
17. Chen Y., Li X., Near-infrared fluorescent nanocapsules with reversible response to thermal/PH modulation for optical imaging. Biomacromolecules 2011 12 12 4367 4372 10.1021/bm201350d 2-s2.0-84863011292
18. Makino A., Kizaka-Kondoh S., Yamahara R., Hara I., Kanzaki T., Ozeki E., Hiraoka M., Kimura S., Near-infrared fluorescence tumor imaging using nanocarrier composed of poly(l-lactic acid)-block-poly(sarcosine) amphiphilic polydepsipeptide. Biomaterials 2009 30 28 5156 5160 10.1016/j.biomaterials.2009.05.046 2-s2.0-67849128549
19. Weissleder R., A clearer vision for in vivo imaging. Nature Biotechnology 2001 19 4 316 317 10.1038/86684 2-s2.0-0035318612
20. Bailey D. L., Willowson K. P., Quantitative SPECT/CT: SPECT joins PET as a quantitative imaging modality. European Journal of Nuclear Medicine and Molecular Imaging 2013 41 1 17 25 10.1007/s00259-013-2542-4 2-s2.0-84883695297
21. Li Y., Rizvi S. M. A., Blair J. M., Cozzi P. J., Qu C. F., Ow K. T., Tam P. N., Perkins A. C., Russell P. J., Allen B. J., Antigenic expression of human metastatic prostate cancer cell lines for in vitro multiple-targeted α -therapy with 213Bi-conjugates. International Journal of Radiation Oncology Biology Physics 2004 60 3 896 908 10.1016/j.ijrobp.2004.04.035 2-s2.0-2942542582
22. Cornelissen B., Darbar S., Hernandez R., Kersemans V., Tullis I., Barber P. R., Smart S., Vojnovic B., Reilly R., Vallis K. A., ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance 111In-DTPA-hEGF auger electron radiation therapy. Journal of Nuclear Medicine 2011 52 5 776 783 10.2967/jnumed.110.084392 2-s2.0-79955768559
23. 111In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer. The Journal of Nuclear Medicine 2007 48 8 1357 1368 10.2967/jnumed.106.037937 2-s2.0-34547786032
24. Cambien B., Franken P. R., Lamit A., Mauxion T., Richard-Fiardo P., Guglielmi J., Crescence L., Mari B., Pourcher T., Darcourt J., Bardiès M., Vassaux G., (TcO4-)-Tc-99m-, auger-mediated thyroid stunning: dosimetric requirements and associated molecular events. PLoS ONE 2014 9 3 e92729 10.1371/journal.pone.0092729 2-s2.0-84899767274
25. Bloomer W. D., Adelstein S. J., 5-125I-iododeoxyuridine as prototype for radionuclide therapy with Auger emitters. Nature 1977 265 5595 620 621 10.1038/265620a0 2-s2.0-0017623694
26. Rossin R., Pan D. P. J., Qi K., Turner J. L., Sun X., Wooley K. L., Welch M. J., 64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: synthesis, radiolabeling, and biologic evaluation. Journal of Nuclear Medicine 2005 46 7 1210 1218 2-s2.0-23844533668
27. Qi K., Ma Q., Remsen E. E., Clark C. G. Jr., Wooley K. L., Determination of the bioavailability of biotin conjugated onto shell cross-linked (SCK) nanoparticles. Journal of the American Chemical Society 2004 126 21 6599 6607 10.1021/ja039647k 2-s2.0-2542551131
28. Sudimack J., Lee R. J., Targeted drug delivery via the folate receptor. Advanced Drug Delivery Reviews 2000 41 2 147 162 10.1016/S0169-409X(99)00062-9 2-s2.0-0343882023
29. Pressly E. D., Rossin R., Hagooly A., Fukukawa K.-I., Messmore B. W., Welch M. J., Wooley K. L., Lamm M. S., Hule R. A., Pochan D. J., Hawker C. J., Structural effects on the biodistribution and positron emission tomograpgy (PET) imaging of well-defined 64Cu-labeled nanoparticles comprised of amphiphilic block graft copolymers. Biomacromolecules 2007 8 10 3126 3134 10.1021/bm700541e 2-s2.0-35548931193
30. Allmeroth M., Moderegger D., Gündel D., Buchholz H.-G., Mohr N., Koynov K., Rösch F., Thews O., Zentel R., PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: a quantitative study using radiolabeling and positron emission tomography. Journal of Controlled Release 2013 172 1 77 85 10.1016/j.jconrel.2013.07.027 2-s2.0-84883550358
31. Allmeroth M., Moderegger D., Gündel D., Koynov K., Buchholz H.-G., Mohr K., Rösch F., Zentel R., Thews O., HPMA-LMA copolymer drug carriers in oncology: an in vivo PET study to assess the tumor line-specific polymer uptake and body distribution. Biomacromolecules 2013 14 9 3091 3101 10.1021/bm400709z 2-s2.0-84883797597
32. Yang Z., Zheng S., Harrison W. J., Harder J., Wen X., Gelovani J. G., Qiao A., Li C., Long-circulating near-infrared fluorescence core-cross-linked polymeric micelles: synthesis, characterization, and dual nuclear/optical imaging. Biomacromolecules 2007 8 11 3422 3428 10.1021/bm7005399 2-s2.0-36649028267
33. Zhang R., Xiong C., Huang M., Zhou M., Huang Q., Wen X., Liang D., Li C., Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts. Biomaterials 2011 32 25 5872 5879 10.1016/j.biomaterials.2011.04.070 2-s2.0-79957918283
34. Hong Y., Zhu H., Hu J., Lin X., Wang F., Li C., Yang Z., Synthesis and radiolabeling of 111In-core-cross linked polymeric micelle-octreotide for near-infrared fluoroscopy and single photon emission computed tomography imaging. Bioorganic and Medicinal Chemistry Letters 2014 24 12 2781 2785 10.1016/j.bmcl.2014.03.050 2-s2.0-84900806513
35. Zhang R., Lu W., Wen X., Huang M., Zhou M., Liang D., Li C., Annexin A5-conjugated polymeric micelles for dual SPECT and optical detection of apoptosis. Journal of Nuclear Medicine 2011 52 6 958 964 10.2967/jnumed.110.083220 2-s2.0-79958136891
36. Jensen A. I., Binderup T., Kumar Ek P., Kjær A., Rasmussen P. H., Andresen T. L., Positron emission tomography based analysis of long-circulating cross-linked triblock polymeric micelles in a U87MG mouse xenograft model and comparison of DOTA and CB-TE2A as chelators of copper-64. Biomacromolecules 2014 15 5 1625 1633 10.1021/bm401871w 2-s2.0-84900441285
37. Okada M., Chemical syntheses of biodegradable polymers. Progress in Polymer Science 2002 27 1 87 133 10.1016/S0079-6700(01)00039-9 2-s2.0-0036466620
38. Hoang B., Lee H., Reilly R. M., Allen C., Noninvasive monitoring of the fate of111in-labeled block copolymer micelles by high resolution and high sensitivity microSPECT/CT imaging. Molecular Pharmaceutics 2009 6 2 581 592 10.1021/mp8002418 2-s2.0-64649097532
39. Lee H., Hoang B., Fonge H., Reilly R. M., Allen C., In vivo distribution of polymeric nanoparticles at the whole-body, tumor, and cellular levels. Pharmaceutical Research 2010 27 11 2343 2355 10.1007/s11095-010-0068-z 2-s2.0-78549283951
40. Reilly R. M., Kiarash R., Cameron R. G., Porlier N., Sandhu J., Hill R. P., Vallis K., Hendler A., Gariépy J., 111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR. Journal of Nuclear Medicine 2000 41 3 429 438 2-s2.0-0033622156
41. Fonge H., Lee H., Reilly R. M., Allen C., Multifunctional block copolymer micelles for the delivery of 111in to EGFR-positive breast cancer cells for targeted Auger electron radiotherapy. Molecular Pharmaceutics 2010 7 1 177 186 10.1021/mp900201v 2-s2.0-76249103637
42. Hoang B., Reilly R. M., Allen C., Block copolymer micelles target auger electron radiotherapy to the nucleus of HER2-positive breast cancer cells. Biomacromolecules 2012 13 2 455 465 10.1021/bm201479t 2-s2.0-84856904042
43. Hoang B., Ekdawi S. N., Reilly R. M., Allen C., Active targeting of block copolymer micelles with trastuzumab fab fragments and nuclear localization signal leads to increased tumor uptake and nuclear localization in HER2-overexpressing xenografts. Molecular Pharmaceutics 2013 10 11 4229 4241 10.1021/mp400315p 2-s2.0-84887346589
44. 111In-labeled polymeric micelles. International Journal of Nanomedicine 2013 8 1385 1391 10.2147/IJN.S42003 2-s2.0-84876256423
45. Peng C.-L., Shih Y.-H., Lee P.-C., Hsieh T. M.-H., Luo T.-Y., Shieh M.-J., Multimodal image-guided photothermal therapy mediated by188Re-labeled micelles containing a cyanine-type photosensitizer. ACS Nano 2011 5 7 5594 5607 10.1021/nn201100m 2-s2.0-79961079165
46. Peng C.-L., Shih Y.-H., Liang K.-S., Chiang P.-F., Yeh C.-H., Tang I.-C., Yao C.-J., Lee S.-Y., Luo T.-Y., Shieh M.-J., Development of in situ forming thermosensitive hydrogel for radiotherapy combined with chemotherapy in a mouse model of hepatocellular carcinoma. Molecular Pharmaceutics 2013 10 5 1854 1864 10.1021/mp3006424 2-s2.0-84877309937
47. Yu D. H., Lu Q., Xie J., Fang C., Chen H. Z., Peptide-conjugated biodegradable nanoparticles as a carrier to target paclitaxel to tumor neovasculature. Biomaterials 2010 31 8 2278 2292 10.1016/j.biomaterials.2009.11.047 2-s2.0-74449088244
48. Sumitani S., Oishi M., Yaguchi T., Murotani H., Horiguchi Y., Suzuki M., Ono K., Yanagie H., Nagasaki Y., Pharmacokinetics of core-polymerized, boron-conjugated micelles designed for boron neutron capture therapy for cancer. Biomaterials 2012 33 13 3568 3577 10.1016/j.biomaterials.2012.01.039 2-s2.0-84862776877
49. Sumitani S., Nagasaki Y., Boron neutron capture therapy assisted by boron-conjugated nanoparticles. Polymer Journal 2012 44 6 522 530 10.1038/pj.2012.30 2-s2.0-84861920967
50. Makino A., Hara E., Hara I., Yamahara R., Kurihara K., Ozeki E., Yamamoto F., Kimura S., Control of in vivo blood clearance time of polymeric micelle by stereochemistry of amphiphilic polydepsipeptides. Journal of Controlled Release 2012 161 3 821 825 10.1016/j.jconrel.2012.05.006 2-s2.0-84864620978
51. Yamamoto F., Yamahara R., Makino A., Kurihara K., Tsukada H., Hara E., Hara I., Kizaka-Kondoh S., Ohkubo Y., Ozeki E., Kimura S., Radiosynthesis and initial evaluation of 18F labeled nanocarrier composed of poly(L-lactic acid)-block-poly(sarcosine) amphiphilic polydepsipeptide. Nuclear Medicine and Biology 2013 40 3 387 394 10.1016/j.nucmedbio.2012.12.008 2-s2.0-84875245502
52. Hara E., Makino A., Kurihara K., Ueda M., Hara I., Kawabe T., Yamamoto F., Ozeki E., Togashi K., Kimura S., Radionuclide therapy using nanoparticle of131I-Lactosome in combination with percutaneous ethanol injection therapy. Journal of Nanoparticle Research 2013 15 2131 10.1007/s11051-013-2131-2 2-s2.0-84887898985
53. Hara E., Makino A., Kurihara K., Yamamoto F., Ozeki E., Kimura S., Pharmacokinetic change of nanoparticulate formulation "Lactosome" on multiple administrations. International Immunopharmacology 2012 14 3 261 266 10.1016/j.intimp.2012.07.011 2-s2.0-84865294413
54. Ishida T., Kiwada H., Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes. International Journal of Pharmaceutics 2008 354 1-2 56 62 10.1016/j.ijpharm.2007.11.005 2-s2.0-40849138014
55. Abu Lila A. S., Kiwada H., Ishida T., The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage. Journal of Controlled Release 2013 172 1 38 47 10.1016/j.jconrel.2013.07.026 2-s2.0-84883504398
56. Hara E., Makino A., Kurihara K., Sugai M., Shimizu A., Hara I., Ozeki E., Kimura S., Evasion from accelerated blood clearance of nanocarrier named as "lactosome" induced by excessive administration of Lactosome. Biochimica et Biophysica Acta-General Subjects 2013 1830 8 4046 4052 10.1016/j.bbagen.2013.03.024 2-s2.0-84877805205
57. Hara E., Ueda M., Makino A., Hara I., Ozeki E., Kimura S., Factors influences in vivo disposition of polymeric micelles on multiple administrations. ACS Medicinal Chemistry Letters 2014 5 8 873 877 10.1021/ml500112u
58. Lu P.-L., Chen Y.-C., Ou T.-W., Chen H.-H., Tsai H.-C., Wen C.-J., Lo C.-L., Wey S.-P., Lin K.-J., Yen T.-C., Hsiue G.-H., Multifunctional hollow nanoparticles based on graft-diblock copolymers for doxorubicin delivery. Biomaterials 2011 32 8 2213 2221 10.1016/j.biomaterials.2010.11.051 2-s2.0-78651443581
59. Wacker M. G., Nanotherapeutics-product development along the nanomaterial discussion. Journal of Pharmaceutical Sciences 2014 103 3 777 784 10.1002/jps.23879 2-s2.0-84894456426