Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes

mBio

Volumn 5, Issue 4, 2014, Pages

  Kaloriti, Despoina ^a   Jacobsen, Mette ^a   Yin, Zhikang ^a   Patterson, Miranda ^b   Tillmann, Anna ^a,f   Smith, Deborah A ^b   Cook, Emily ^c   You, Tao ^a   Grimm, Melissa J ^d   Bohovych, Iryna ^a   Grebogi, Celso ^a   Segal, Brahm H ^d,e   Gow, Neil A R ^a   Haynes, Ken ^c   Quinn, Janet ^b   Brown, Alistair J P ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF EXETER   (United Kingdom)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

^e UNIVERSITY AT BUFFALO   (United States)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; PROTEIN HOG1; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTOME; UNCLASSIFIED DRUG; ACETOPHENONE DERIVATIVE; APOCYNIN; GLIBENCLAMIDE;

ADAPTATION; ARTICLE; CANDIDA ALBICANS; CATIONIC STRESS; CELL DEATH; CELL STRESS; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGAL CELL; FUNGAL STRAIN; FUNGUS GROWTH; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROARRAY ANALYSIS; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTE; PHAGOCYTOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WESTERN BLOTTING; DRUG EFFECTS; METABOLISM; PHYSIOLOGY;

CANDIDA ALBICANS;

ACETOPHENONES; CANDIDA ALBICANS; GLYBURIDE; HUMANS; NEUTROPHILS; OXIDATIVE STRESS; PHAGOCYTES;

EID: 84908303450     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01334-14     Document Type: Article

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