Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling

Immunology

Volumn 143, Issue 3, 2014, Pages 341-353

  Shabani, Mahdi ^a,b   Bayat, Ali Ahmad ^a   Jeddi Tehrani, Mahmood ^a   Rabbani, Hodjatallah ^a,c   Hojjat Farsangi, Mohammad ^d   Ulivieri, Cristina ^e   Amirghofran, Zahra ^b   Baldari, Cosima Tatiana ^e   Shokri, Fazel ^a,f  

^a AVICENNA RESEARCH INSTITUTE   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UNIVERSITY OF SIENA   (Italy)

^f TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

B cell receptor signalling; Fc receptor like 2; Monoclonal antibody

Indexed keywords

B LYMPHOCYTE RECEPTOR; FC RECEPTOR LIKE 1; FC RECEPTOR LIKE 2; FC RECEPTOR LIKE 3; FC RECEPTOR LIKE 4; FC RECEPTOR LIKE 5; GLYCOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; CALCIUM; CELL SURFACE RECEPTOR; FCRL2 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; BURKITT LYMPHOMA CELL LINE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONTROLLED STUDY; CROSS REACTION; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FLUORESCENCE ACTIVATED CELL SORTING; HYBRIDOMA; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; IMMUNORECEPTOR TYROSINE BASED INHIBITION MOTIF; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION;

ANIMALS; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; CALCIUM; CELL LINE; CHO CELLS; CRICETULUS; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 84908283002     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12311     Document Type: Article

References (32)

1. Gauld SB, Dal Porto JM, Cambier JC. B cell antigen receptor signaling: roles in cell development and disease. Science 2002; 296:1641-2.
2. Dal Porto JM, Gauld SB, Merrell KT et al. B cell antigen receptor signaling 101. Mol Immunol 2004; 41:599-613.
3. Weinstein E, Peeva E, Putterman C et al. B-cell biology. Rheum Dis Clin North Am 2004; 30:159-74.
4. Kurosaki T. Regulation of BCR signaling. Mol Immunol 2011; 48:1287-91.
5. Leu CM, Davis RS, Gartland LA et al. FcRH1: an activation coreceptor on human B cells. Blood 2005; 105:1121-6.
6. Jackson TA, Haga CL, Ehrhardt GR et al. FcR-like 2 Inhibition of B cell receptor-mediated activation of B cells. J Immunol 2010; 185:7405-12.
7. Ehrhardt GR, Davis RS, Hsu JT et al. The inhibitory potential of Fc receptor homolog 4 on memory B cells. Proc Natl Acad Sci USA 2003; 100:13489-94.
8. Davis RS. Fc receptor-like molecules. Annu Rev Immunol 2007; 25:525-60.
9. Hatzivassiliou G, Miller I, Takizawa J et al. IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy. Immunity 2001; 14:277-89.
10. Davis RS, Wang YH, Kubagawa H et al. Identification of a family of Fc receptor homologs with preferential B cell expression. Proc Natl Acad Sci USA 2001; 98:9772-7.
11. Nakayama Y, Weissman SM, Bothwell AL. BXMAS1 identifies a cluster of homologous genes differentially expressed in B cells. Biochem Biophys Res Commun 2001; 285:830-7.
12. Xu MJ, Zhao R, Zhao ZJ. Molecular cloning and characterization of SPAP1, an inhibitory receptor. Biochem Biophys Res Commun 2001; 280:768-75.
13. Haga CL, Ehrhardt GR, Boohaker RJ et al. Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment. Proc Natl Acad Sci USA 2007; 104:9770-5.
14. Kochi Y, Myouzen K, Yamada R et al. FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling. J Immunol 2009; 183:5502-10.
15. Sohn HW, Krueger PD, Davis RS et al. FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling. Blood 2011; 118:6332-41.
16. Miller I, Hatzivassiliou G, Cattoretti G et al. IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells. Blood 2002; 99:2662-9.
17. Polson AG, Zheng B, Elkins K et al. Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia. Int Immunol 2006; 18:1363-73.
18. Huttmann A, Klein-Hitpass L, Thomale J et al. Gene expression signatures separate Bcell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status. Leukemia 2006; 20:1774-82.
19. Kazemi T, Asgarian-Omran H, Hojjat-Farsangi M et al. Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia. Int J Cancer 2008; 123:2113-9.
20. Li FJ, Ding S, Pan J et al. FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia. Blood 2008; 112:179-87.
21. Magrath IT, Freeman CB, Pizzo P et al. Characterization of lymphoma-derived cell lines: comparison of cell lines positive and negative for Epstein-Barr virus nuclear antigen. II. Surface markers. J Natl Cancer Inst 1980; 64:477-83.
22. Ben-Bassat H, Goldblum N, Mitrani S et al. Establishment in continuous culture of a new type of lymphocyte from a "Burkitt like" malignant lymphoma (line D.G.-75). Int J Cancer 1977; 19:27-33.
23. Shabani M, Hemmati S, Hadavi R et al. Optimization of gene transfection in murine myeloma cell lines using different transfection reagents. AJMB 2010; 2:123-30.
24. Asgarian-Omran H, Amirzargar AA, Arjmand M et al. Expression, purification and characterization of three overlapping immunodominant recombinant fragments from Bordetella pertussis filamentous hemagglutinin. Avicenna J Med Biotechnol 2013; 5:20-8.
25. Kazemi T, Tahmasebi F, Bayat AA et al. Characterization of novel murine monoclonal antibodies directed against the extracellular domain of human HER2 tyrosine kinase receptor. Hybridoma (Larchmt) 2011; 30:347-53.
26. Ghittoni R, Patrussi L, Pirozzi K et al. Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases. Faseb J 2005; 19:605-7.
27. Won WJ, Foote JB, Odom MR et al. Fc receptor homolog 3 is a novel immunoregulatory marker of marginal zone and B1 B cells. J Immunol 2006; 177:6815-23.
28. Kochi Y, Yamada R, Suzuki A et al. A functional variant in FCRL3, encoding Fc receptor- like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet 2005; 37:478-85.
29. Mackay M, Stanevsky A, Wang T et al. Selective dysregulation of the FccIIB receptor on memory B cells in SLE. J Exp Med 2006; 203:2157-64.
30. Su K, Yang H, Li X et al. Expression profile of FccRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J Immunol 2007; 178:3272-80.
31. Isaak A, Gergely P Jr, Szekeres Z et al. Physiological up-regulation of inhibitory receptors FccRII and CR1 on memory B cells is lacking in SLE patients. Int Immunol 2008; 20:185-92.
32. Catalan D, Aravena O, Sabugo F et al. B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy. Arthritis Res Ther 2010; 12: R68.