Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study

Life Sciences

Volumn 116, Issue 1, 2014, Pages 8-15

  Guimarães, Adriana G ^a   Scotti, Luciana ^b   Scotti, Marcus Tullius ^b   Mendonҫa, Francisco J B ^c   Melo, Nayara S R ^a   Alves, Rafael S ^a   De Lucca, Waldecy ^a   Bezerra, Daniel P ^d   Gelain, Daniel P ^e   Quintans, Lucindo J ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^c STATE UNIVERSITY OF PARAÍBA   (Brazil)

^d INSTITUTO OSWALDO CRUZ   (Brazil)

^e FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Cancer pain; Carvacrol; Hyperalgesia; Monoterpene; Nociception

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CARVACROL; INTERLEUKIN 10; MORPHINE; MUSCIMOL; PROTEIN FOS; ANALGESIC AGENT; TERPENE;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CANCER PAIN; CONTROLLED STUDY; DRUG MECHANISM; FORELIMB; GRIP STRENGTH; HYPERALGESIA; LOCUS CERULEUS; LUMBAR SPINAL CORD; MALE; MECHANICAL STIMULATION; MOLECULAR DOCKING; MOUSE; MOVEMENT EVOKED NOCICEPTION; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; PALPATION INDUCED NOCICEPTION; PERIAQUEDUCTAL GRAY MATTER; PROTEIN PROTEIN INTERACTION; RAPHE MAGNUS NUCLEUS; SARCOMA 180; SARCOMA CELL; TUMOR GROWTH; ANIMAL; COMPLICATION; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PAIN; PATHOLOGY; SPINAL CORD;

ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERALGESIA; INTERLEUKIN-10; MALE; MICE; MOLECULAR DOCKING SIMULATION; MONOTERPENES; MUSCIMOL; NOCICEPTION; PAIN; PERIAQUEDUCTAL GRAY; RECEPTORS, GABA-A; SARCOMA 180; SPINAL CORD;

EID: 84908275057     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.08.020     Document Type: Article

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