Ethanol induced impairment of glucose metabolism involves alterations of GABAergic signaling in pancreatic β-cells

Toxicology

Volumn 326, Issue , 2014, Pages 44-52

  Wang, Shuanglian ^a   Luo, Yan ^b   Feng, Allen ^b,c   Li, Tao ^a   Yang, Xupeng ^a   Nofech Mozes, Roy ^b,c   Yu, Meng ^a   Wang, Changhui ^a   Li, Ziwei ^a   Yi, Fan ^a   Liu, Chuanyong ^a   Lu, Wei Yang ^b,c  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Alcohol overindulgence; GABA receptor; Glucose metabolism; Insulin; Pancreatic islet cells

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA; ALCOHOL; GLUCOSE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; GABRA1 PROTEIN, MOUSE; GABRA1 PROTEIN, RAT; GLUCOSE BLOOD LEVEL; INSULIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD GLUCOSE METER; CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; ELISA KIT; GABAERGIC SYSTEM; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATCH CLAMP TECHNIQUE; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG EFFECTS; MEMBRANE POTENTIAL; METABOLISM; SECRETION (PROCESS); TIME; TOXICITY;

ANIMALS; BLOOD GLUCOSE; CELL LINE; ETHANOL; GABA-A RECEPTOR AGONISTS; GABA-A RECEPTOR ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; INSULIN; INSULIN-SECRETING CELLS; MALE; MEMBRANE POTENTIALS; MICE; RATS; RECEPTORS, GABA-A; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84908266417     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.10.005     Document Type: Article

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