Phenylalanine binding is linked to dimerization of the regulatory domain of phenylalanine hydroxylase

Biochemistry

Volumn 53, Issue 42, 2014, Pages 6625-6627

  Zhang, Shengnan ^a   Roberts, Kenneth M ^a   Fitzpatrick, Paul F ^a  

^a University of Texas Health Science Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE HYDROXYLASE; REGULATORY DOMAIN;

DIMER; MONOMER; PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; PROTEIN BINDING; SERINE;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL BINDING; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIMERIZATION; DISSOCIATION CONSTANT; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; ENZYME STABILITY; ENZYME STRUCTURE; PROTEIN DOMAIN; STRUCTURE ANALYSIS; ULTRACENTRIFUGATION; CHEMISTRY; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

DIMERIZATION; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SERINE;

EID: 84908264368     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi501109s     Document Type: Article

References (16)

1. Fitzpatrick, P. F. (2012) Arch. Biochem. Biophys. 519, 194-201
2. Shiman, R., Jones, S. H., and Gray, D. W. (1990) J. Biol. Chem. 265, 11633-11642
3. Li, J., Dangott, L. J., and Fitzpatrick, P. F. (2010) Biochemistry 49, 3327-3335
4. Doskeland, A. P., Martinez, A., Knappskog, P. M., and Flatmark, T. (1996) Biochem. J. 313, 409-414
5. Kobe, B., Jennings, I. G., House, C. M., Michell, B. J., Goodwill, K. E., Santarsiero, B. D., Stevens, R. C., Cotton, R. G. H., and Kemp, B. E. (1999) Nat. Struct. Biol. 6, 442-448
6. Fitzpatrick, P. F. (1999) Annu. Rev. Biochem. 68, 355-381
7. Wang, L., Erlandsen, H., Haavik, J., Knappskog, P. M., and Stevens, R. C. (2002) Biochemistry 41, 12569-12574
8. Goodwill, K. E., Sabatier, C., Marks, C., Raag, R., Fitzpatrick, P. F., and Stevens, R. C. (1997) Nat. Struct. Biol. 4, 578-585
9. Fitzpatrick, P. F. (2003) Biochemistry 42, 14083-14091
10. Zhang, S., Huang, T., Ilangovan, U., Hinck, A. P., and Fitzpatrick, P. F. (2014) J. Mol. Biol. 426, 1483-1497
11. Li, J., Ilangovan, U., Daubner, S. C., Hinck, A. P., and Fitzpatrick, P. F. (2011) Arch. Biochem. Biophys. 505, 250-255
12. Jaffe, E. K., Stith, L., Lawrence, S. H., Andrake, M., and Dunbrack, R. L., Jr. (2013) Arch. Biochem. Biophys. 530, 73-82
13. Demeler, B. (2005) in Modern Analytical Ultracentrifugation: Techniques and Methods (Scott, D. J., Harding, S. E., and Rowe, A. J., Eds.) pp 210-229, Royal Society of Chemistry, London.
14. Gabrielson, J. P., Randolph, T. W., Kendrick, B. S., and Stoner, M. R. (2007) Anal. Biochem. 361, 24-30
15. Johnson, K. A., Simpson, Z. B., and Blom, T. (2009) Anal. Biochem. 387, 20-29
16. Grant, G. A. (2006) J. Biol. Chem. 281, 33825-33829