Deprescribing medication for frail elderly patients in nursing homes: A survey of vancouver family physicians

British Columbia Medical Journal

Volumn 56, Issue 9, 2014, Pages 436-441

  Harriman, Kasandra ^a   Howard, Lisa ^b   McCracken, Rita ^c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Providence Health Care ^*  (Canada)

^c Providence Healthcare   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84908255021     PISSN: 00070556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Heppner HJ, Christ M, Gosch M, et al. Polypharmacy in the elderly from the clinical toxicologist perspective. Z Gerontol Geriatr 2012;45:473-478.
2. Frazier SC. Health outcomes and polypharmacy in elderly individuals: An integrated literature review. J Gerontol Nurs 2005;31:4-11.
3. Jyrkka J, Enlund H, Korhonen MJ, et al. Polypharmacy status as an indicator of mortality in an elderly population. Drugs Aging 2009;26:1039-1048.
4. Hamilton HJ, Gallagher PF, O’Mahony D. Inappropriate prescribing and adverse drug events in older people. BMC Geriatr 2009;9:5.
5. Ramage-Morin PL. Medication use among senior Canadians. Health Rep 2009;20:37-44.
6. Sera LC, McPherson ML. Pharmacokinetics and pharmacodynamic changes associated with aging and implications for drug therapy. Clin Geriatr Med 2012;28:273-286.
7. Haasum Y, Fastbom J, Johnell K. Institutionalization as a risk factor for inappropriate drug use in the elderly: A Swedish nationwide register-based study. Ann Pharmacother 2012;46:339-346.
8. Mangoni AA, van Munster BC, Woodman RJ, et al. Measures of anticholinergic drug exposure, serum anticholinergic activity, and all-cause postdischarge mortality in older hospitalized patients with hip fractures. Am J Geriatr Psychiatry 2013;21: 785-793.
9. Hilmer SN, Gnjidic D, Abernethy DR. Pharmacoepidemiology in the postmarketing assessment of the safety and efficacy of drugs in older adults. J Gerontol A Biol Sci Med Sci 2012;67:181-188.
10. Tinetti ME, Bogardus ST, Jr., Agostini JV. Potential pitfalls of disease-specific guidelines for patients with multiple conditions. N Engl J Med 2004;351:2870-2874.
11. Fialova D, Onder G. Medication errors in elderly people: Contributing factors and future perspectives. Br J Clin Pharmacol 2009;67:641-645.
12. Linjakumpu T, Hartikainen S, Klaukka T, et al. Use of medications and polypharmacy are increasing among the elderly. J Clin Epidemiol 2002;55:809-817.
13. Patterson SM, Hughes C, Kerse N, et al. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev 2012;5: CD008165.
14. Alldred DP, Raynor DK, Hughes C, et al. Interventions to optimise prescribing for older people in care homes. Cochrane Database Syst Rev 2013;2:CD009095.
15. Forsetlund L, Eike MC, Gjerberg E, et al. Effect of interventions to reduce potentially inappropriate use of drugs in nursing homes: A systematic review of randomised controlled trials. BMC Geriatr 2011;11:16.
16. Gnjidic D, Le Couteur DG, Kouladjian L, et al. Deprescribing trials: Methods to reduce polypharmacy and the impact on prescribing and clinical outcomes. Clin Geriatr Med 2012;28:237-253.
17. Gnjidic D, Le Couteur DG, Abernethy DR, et al. A pilot randomized clinical trial utilizing the drug burden index to reduce exposure to anticholinergic and sedative medications in older people. Ann Pharmacother 2010;44:1725-1732.
18. Garfinkel D, Zur-Gil S, Ben-Israel J. The war against polypharmacy: A new costeffective geriatric-palliative approach for improving drug therapy in disabled elderly people. Isr Med Assoc J 2007;9:430-434.
19. Garfinkel D, Mangin D. Feasibility study of a systematic approach for discontinuation of multiple medications in older adults: Addressing polypharmacy. Arch Intern Med 2010;170:1648-1654.
20. Anthierens S, Tansens A, Petrovic M, et al. Qualitative insights into general practitioners views on polypharmacy. BMC Fam Pract 2010;11:65.
21. Schuling J, Gebben H, Veehof LJ, et al. Deprescribing medication in very elderly patients with multimorbidity: The view of Dutch GPs. A qualitative study. BMC Fam Pract 2012;13:56.
22. Iyer S, Naganathan V, McLachlan AJ, et al. Medication withdrawal trials in people aged 65 years and older: A systematic review. Drugs Aging 2008;25:1021-1031.
23. Harrington C, Choiniere J, Goldmann M, et al. Nursing home staffing standards and staffing levels in six countries. J Nurs Scholarsh 2012;44:88-98.
24. Tinetti ME, Fried TR, Boyd CM. Designing health care for the most common chronic condition--multimorbidity. JAMA 2012; 307:2493-2494.
25. Farrell B, Shamji S, Monahan A, et al. Clinical vignettes to help you deprescribe medications in elderly patients: Introduction to the polypharmacy case series. Can Fam Physician 2013;59:1257-1258.