Osteochondral tissue regeneration through polymeric delivery of DNA encoding for the SOX trio and RUNX2

Acta Biomaterialia

Volumn 10, Issue 10, 2014, Pages 4103-4112

  Needham, Clark J ^a   Shah, Sarita R ^a   Dahlin, Rebecca L ^a   Kinard, Lucas A ^a   Lam, Johnny ^a   Watson, Brendan M ^a   Lu, Steven ^a   Kasper, F Kurtis ^a   Mikos, Antonios G ^a  

^a Rice University   (United States)

Author keywords

bPEI HA; OPF; Polymeric gene delivery; RUNX 2; SOX trio

Indexed keywords

BONE; CARTILAGE; COMPUTERIZED TOMOGRAPHY; DNA; ENCODING (SYMBOLS); GENE THERAPY; HYALURONIC ACID; HYDROGELS; POLYETHYLENE GLYCOLS; QUALITY CONTROL; REPAIR; SCAFFOLDS (BIOLOGY); SIGNAL ENCODING; TISSUE REGENERATION; TRANSCRIPTION;

BRANCHED POLY(ETHYLENIMINE)-HYALURONIC ACID; DNA ENCODING; GENE DELIVERY; OPF; OSTEOCHONDRAL TISSUES; POLY(ETHYLENIMINE); POLYMERIC DELIVERY; POLYMERIC GENE DELIVERY; RUNX-2; SOX TRIO;

GENE TRANSFER;

HYALURONIC ACID; MACROGOL DERIVATIVE; MOLECULAR SCAFFOLD; OLIGO[POLY(ETHYLENE GLYCOL) FUMARATE]; POLYETHYLENEIMINE; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX; TRANSCRIPTION FACTOR SOX5; TRANSCRIPTION FACTOR SOX6; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; DNA; HYDROGEL; OLIGO(POLY(ETHYLENE GLYCOL)FUMARATE); POLYESTER; RUNX2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE REGENERATION; CARTILAGE INJURY; CARTILAGE REGENERATION; COMPLEX FORMATION; CONTROLLED STUDY; EXPLANT; GENE TARGETING; GENE THERAPY; HEALING; HISTOPATHOLOGY; HYDROGEL; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; RAT; TISSUE REGENERATION; TISSUE REPAIR; ANIMAL; BIOSYNTHESIS; BONE; CARTILAGE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; INJURIES; LEWIS RAT; METABOLISM; PHARMACOLOGY; PROCEDURES; RADIOGRAPHY;

ANIMALS; BONE AND BONES; BONE REGENERATION; CARTILAGE; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA; GENETIC THERAPY; HYALURONIC ACID; HYDROGELS; POLYESTERS; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; RATS; RATS, INBRED LEW; SOX TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84908253782     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.05.011     Document Type: Article

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