Biocompatible electrospun polymer blends for biomedical applications

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 102, Issue 7, 2014, Pages 1517-1527

  Munj, Hrishikesh Ramesh ^a   Tyler Nelson, M ^a   Karandikar, Prathamesh Sadanand ^a   Lannutti, John Joseph ^a   Tomasko, David Lane ^a  

^a The Ohio State University   (United States)

Author keywords

Electrospinning; Impregnation; Polymer blends; Supercritical CO2

Indexed keywords

BIOCOMPATIBILITY; BIOMECHANICS; BIOMIMETIC PROCESSES; CARBON DIOXIDE; CELL PROLIFERATION; CONTROLLED DRUG DELIVERY; DEGRADATION; ELECTROSPINNING; FUNCTIONAL POLYMERS; IMPREGNATION; MECHANICAL PROPERTIES; MEDICAL APPLICATIONS; NATURAL POLYMERS; RHODAMINE B; SCAFFOLDS (BIOLOGY); STRESS RELAXATION; TARGETED DRUG DELIVERY; TISSUE REGENERATION;

BIOACTIVE PROPERTIES; BIOCOMPATIBLE POLYMER; BIOMEDICAL APPLICATIONS; ELECTROSPUN POLYMERS; ELECTROSPUN SCAFFOLDS; INDIVIDUAL COMPONENTS; SUPERCRITICAL CO2; SYNTHETIC POLYMERS;

POLYMER BLENDS;

BIOMATERIAL; CARBON DIOXIDE; GELATIN; MOLECULAR SCAFFOLD; POLY(METHYL METHACRYLATE); POLYCAPROLACTONE; RHODAMINE B; POLYESTER;

ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; BIOMIMETICS; CELL GROWTH; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; ELECTROSPINNING; POROSITY; TENSILE STRENGTH; TISSUE REPAIR; CHEMISTRY; ELECTROCHEMICAL ANALYSIS;

BIOCOMPATIBLE MATERIALS; DRUG DELIVERY SYSTEMS; ELECTROCHEMICAL TECHNIQUES; GELATIN; POLYESTERS; POLYMETHYL METHACRYLATE;

EID: 84908238375     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.33132     Document Type: Article

References (56)

1. Lee K, Silva EA, Mooney DJ. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments. J R Soc Interface 2011;8:153-170.
2. Nisbet DR, Forsythe JS, Shen W, Finkelstein DI, Horne MK. Review paper: A review of the cellular response on electrospun nanofibers for tissue engineering. J Biomater Appl 2009;24:7-29.
3. Jagur-Grodzinski J. Polymers for tissue engineering, medical devices, and regenerative medicine. Concise general review of recent studies. Polym Adv Technol 2006;17:395-418.
4. Gloria A, De Santis R, Ambrosio L. Polymer-based composite scaffolds for tissue engineering. J Appl Biomater Biomechanics 2010;8:57-67.
5. Place ES, George JH, Williams CK, Stevens MM. Synthetic polymer scaffolds for tissue engineering. Chem Soc Rev 2009;38: 1139-1151.
6. Ulery BD, Nair LS, Laurencin CT. Biomedical applications of biodegradable polymers. J Polym Sci Part B: Polym Phys 2011;49: 832-864.
7. Dash TK, Badireenath Konkimalla V. Poly-ε-caprolactone based formulations for drug delivery and tissue engineering: A review. J Controlled Release 2012;158:15-33.
8. Vaz CM, Van Tuijl S, Bouten CVC, Baaijens FPT. Design of scaffolds for blood vessel tissue engineering using a multi-layering electrospinning technique. Acta Biomaterialia 2005;1:575-582.
9. Ghasemi-Mobarakeh L, Prabhakaran MP, Morshed M, Nasr- Esfahani MH, Ramakrishna S. Electrospun poly(e-caprolactone)/gelatin nanofibrous scaffolds for nerve tissue engineering. Biomater 2008;29:4532-4539.
10. Mano JF, Sousa RA, Boesel LF, Neves NM, Reis RL. Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: State of the art and recent developments. Compos Sci Technol 2004;64:789-817.
11. Zhang F, Sun F, Van Kan JA, Shao PG, Zheng Z, Ge RW, Watt F. Measurement of cell motility on proton beam micromachined 3D scaffolds. Nucl Instrum Methods Phys Res Sect B 2005;231:413- 418.
12. Srouji S, Kizhner T, Livne E. 3D scaffolds for bone marrow stem cell support in bone repair. Future Med 2006;1:519-528.
13. Liu X, Holzwarth JM, Ma PX. Functionalized synthetic biodegradable polymer scaffolds for tissue engineering. Macromol Biosci 2012;12:911-919.
14. Liu X, Won Y, Ma PX. Porogen-induced surface modification of nano-fibrous poly(L-lactic acid) scaffolds for tissue engineering. Biomaterials 2006;27:3980-3987.
15. Liu X, Won Y, Ma PX. Surface modification of interconnected porous scaffolds. J Biomed Mater Res A 2005;74:84-91.
16. Sionkowska A. Current research on the blends of natural and synthetic polymers as new biomaterials: Review. Prog Polym Sci 2011;36.9:1254-1276.
17. Pant HR, Kim CS. Electrospun gelatine/nylon-6 composite nanofibers for biomedical applications. Polym Int 2012;62:1008-1013.
18. Duarte ARC, Mano JF, Reis RL. Supercritical fluids in biomedical and tissue engineering applications: A review. Int Mater Rev 2009;54:214-222.
19. Bhamidipati M, Scurto AM, Detamore MS. The future of carbon dioxide for polymer processing in tissue engineering. Tissue Eng Part B: Rev 2013;19:221-232.
20. Duarte ARC, Santo VE, Alves A, Silva SS, Moreira-Silva J, Silva TH, Marques AP, Sousa RA, Gomes ME, Mano JF, Reis RL. Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine. J Supercrit Fluids 2013;79:177-185.
21. Yanhui Y, Teja AS. Quantification of specific interactions between CO2 and the carbonyl group in polymers via ATR-FTIR measurements. J Supercrit Fluids 2011;56:208-212.
22. Tomasko DL, Li H, Liu D, Han X, Wingert MJ, Lee LJ, Koelling KW. A Review of CO2 Applications in the processing of polymers. Ind Eng Chem Res 2003;42:6431-6456.
23. Roshan Y, Mammucari R, Foster NR. Impregnation of ibuprofen into polycaprolactone using supercritical carbon dioxide. J Phys: Conf Ser 2010;215:012087.
24. Yazan HA, Grant CS. Ibuprofen impregnation into submicron polymeric films in supercritical carbon dioxide. J Supercrit Fluids 2012;71:127-135.
25. Ayodeji O, Graham E, Kniss D, Lannutti JJ, Tomasko DL. Carbon dioxide impregnation of electrospun polycaprolactone fibers. J Supercrit Fluids 2007;41:173-178.
26. Kamiya Y, Mizoguchi K, Terada K, Fujiwara Y, Wang JS. CO2 sorption and dilation of poly(methyl methacrylate). Macromolecules 1998;31:472-478.
27. Di Noto V, Vezzu K, Giffin GA, Conti F, Bertucco A. Effect of High Pressure CO2 on the Structure of PMMA: A FT-IR Study. J Phys Chem B 2011;115:13519-13525.
28. Nelson MT, Munj HR, Tomasko DL, Lannutti JJ. Carbon dioxide infusion of composite electrospun fibers for tissue engineering. J Supercrit Fluids 2012;70:90-99.
29. Kumari S, Basha SK, Sudha PN. Physicochemical and morphological evaluation of chitosan/poly (vinyl alcohol)/methylcellulose chemically cross-linked ternary blends. Polym Bull 2012;68:1387-1393.
30. Liu H, Song W, Chen F, Guo L, Zhang J. Interaction of microstructure and interfacial adhesion on impact performance of polylactide (PLA) ternary blends. Macromolecules 2011;44: 1513-1522.
31. Grande R, Carvalho AJ. Compatible ternary blends of chitosan/poly (vinyl alcohol)/poly (lactic acid) produced by oil-in-water emulsion processing. Biomacromolecules 2011;12:907-914.
32. Mudigoudra BS, Masti SP, Chougale RB. Thermal behavior of poly (vinyl alcohol)/poly (vinyl pyrrolidone)/chitosan ternary polymer blend films. Res J Recent Sci 2012;1:83-86.
33. Gu SY, Wang ZM, Ren J, Zhang CY. Electrospinning of gelatin and gelatin/poly(L-lactide) blend and its characteristics for wound dressing. Mater Sci Eng C 2009;29:1822-1828.
34. Kim CH, Cho KY, Choi EJ, Park JK. Effect of P(lLA-co-eCL) on the compatibility and crystallization behavior of PCL/PLLA blends. J Appl Polym Sci 2000;77:226-231.
35. Domanska U, Pobudkowska A, Pelczarska A, Gierycz P. pKa and solubility of drugs in water, ethanol, and 1-octanol. J Phys Chem B 2009;113:8941-8947.
36. Jopling DW. Stress relaxation studies of chemically crosslinked gelatin films. J Polym Sci Part A: Gen Pap 1965;3:513-526.
37. Sarti GC, Gostoli C, Masoni S. Diffusion of alcohols and relaxation in poly(methyl methacrylate): Effect of thermal history. J Membr Sci 1983;15:181-192.
38. Matthews RG, Ajji A, Dumoulin MM, Prud'homme RE. The effects of stress relaxation on the structure and orientation of tensile drawn poly(ethylene terephthalate). Polymer 2000;41: 7139-7145.
39. Shen Z, McHugh MA, Xu J, Belardi J, Kilic S, Mesiano A, Bane S, Karnikas C, Beckman E, Enick R. CO2-solubility of oligomers and polymers that contain the carbonyl group. Polymer 2003;44:1491- 1498.
40. Shieh YT, Yang HS. Morphological changes of polycaprolactone with high-pressure CO2 treatment. J Supercrit Fluids 2005;33:183- 192.
41. Liu D, Li H, Noon MS, Tomasko DL. CO2-Induced PMMA swelling and multiple thermodynamic property analysis using sanchez lacombe EOS. Macromolecules 2005;38:4416-4424.
42. Tan EPS, Ng SY, Lim CT. Tensile testing of a single ultrafine polymeric fiber. Biomaterials 2005;26:1453-1456.
43. Mousa WF, Kobayashi M, Shinzato S, Kamimura M, Neo M, Yoshihara S, Nakamura T. Biological and mechanical properties of PMMA-based bioactive bone cements. Biomaterials 2000;21: 2137-2146.
44. Yakimets I, Wellner N, Smith AC, Wilson RH, Farhat I, Mitchell J. Mechanical properties with respect to water content of gelatin films in glassy state. Polymer 2005;46:12577-12585.
45. Zhang YZ, Venugopal J, Huang ZM, Lim CT, Ramakrishna S. Crosslinking of the electrospun gelatin nanofibers. Polymer 2006; 47:2911-2911.
46. Kikic I, Vecchione F. Supercritical impregnation of polymers. Curr Opin Solid State Mater Sci 2003;7:399-405.
47. Freiberg S, Zhu XX. Polymer microspheres for controlled drug release. Int J Pharm 2004;282:1-18.
48. Varnell DF, Coleman MM. FTIR studies of polymer blends: V. Further observations on polyester-poly(vinyl chloride) blends. Polymer 1981;22:1324-1328.
49. Singh YP, Singh RP. Compatibility studies on solutions of polymer blends by viscometric and ultrasonic techniques. Eur Polym J 1983;19:535-541.
50. Hancock BC, York P, Rowe RC. The use of solubility parameters in pharmaceutical dosage form design. Int J Pharm 1997;148:1-21.
51. Stefanis E, Panayiotou C. Prediction of hansen solubility parameters with a new group-contribution method. Int J Thermophys 2008;29:568-585.
52. Shirahase T, Komatsu Y, Tominaga Y, Asai S, Sumita M. Miscibility and hydrolytic degradation in alkaline solution of poly(l-lactide) and poly(methyl methacrylate) blends. Polymer 2006;47: 4839-4844.
53. Li WJ, Cooper Jr JA, Mauck RL, Tuan RS. Fabrication and characterization of six electrospun poly(a-hydroxy ester)-based fibrous scaffolds for tissue engineering applications. Acta Biomater 2006; 2:377-385.
54. Bigi A, Cojazzi G, Panzavolta S, Rubini K, Roveri N. Mechanical and thermal properties of gelatin films at different degrees of glutaraldehyde crosslinking. Biomaterials 2001;22:763-768.
55. Wissinger RG, Paulaitis ME. Swelling and sorption in polymer- CO2 mixtures at elevated pressures. J Polym Sci Part B: Polym Phys 1987;25:2497-2510.
56. Ritger PL, Peppas NA. A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J Controlled Release 1987;5:37-42.