Surface charge and dosage dependent potential developmental toxicity and biodistribution of iron oxide nanoparticles in pregnant CD-1 mice

Reproductive Toxicology

Volumn 50, Issue , 2014, Pages 36-42

  Di Bona, Kristin R ^a   Xu, Yaolin ^b   Ramirez, Paul A ^a   DeLaine, Javeia ^a   Parker, Courtney ^a   Bao, Yuping ^b   Rasco, Jane F ^a  

^a UNIVERSITY OF ALABAMA   (United States)

^b University of Alabama   (United States)

Author keywords

Bioaccumulation; Developmental toxicity; Fetotoxicity; Iron; Iron oxide nanoparticles; Nanoparticles

Indexed keywords

IRON OXIDE; IRON OXIDE NANOPARTICLE; NANOPARTICLE; UNCLASSIFIED DRUG; FERRIC ION; FERRIC OXIDE; METAL NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CD-1 MOUSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DAM (ANIMAL); DEVELOPMENTAL TOXICITY; FEMALE; FETUS; FETUS DEATH; FETUS LIVER; LITTER SIZE; MOUSE; NANOTOXICOLOGY; NONHUMAN; PLACENTA; PRENATAL EXPOSURE; SURFACE CHARGE; TISSUE DISTRIBUTION; ANIMAL; CHEMISTRY; DRUG EFFECTS; MALE; METABOLISM;

ANIMALS; FEMALE; FERRIC COMPOUNDS; FETUS; MALE; METAL NANOPARTICLES; MICE; TISSUE DISTRIBUTION;

EID: 84908230379     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2014.09.010     Document Type: Article

References (53)

1. United States Government Accountability Office Report on Nanotechnology Nanomaterials Are Widely Used in Commerce, but EPA Faces Challenges in Regulating Risk. Int J Occup Environ Health 2010, 16:525-39.
2. Powers M. Nanomedicine and nano device pipeline surges 68%. NanoBiotech News 2006, 1-69.
3. Linkov I., Satterstrom F.K., Corey L.M. Nanotoxicology and nanomedicine: making hard decisions. Nanomedicine-Nanotechnol Biol Med 2008, 4:167-171.
4. Oberdorster G. Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology. J Inter Med 2010, 267:89-105.
5. Teli M.K., Mutalik S., Rajanikant G.K. Nanotechnology and Nanomedicine: going small means aiming big. Curr Pharmaceut Design 2010, 16:1882-1892.
6. Fadeel B., Garcia-Bennett A.E. Better safe than sorry: understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. Adv Drug Del Rev 2010, 62:362-374.
7. Li W.-q., Sun C.-y., Wang F., Wang Y.-c., Zhai Y.-w., Liang M., et al. Achieving a new controllable male contraception by the photothermal effect of gold nanorods. Nano Lett 2013, 13:2477-2484.
8. Caruso F., Hyeon T., Rotello V. Nanomedicine. Chem Soc Rev 2012, 41:2537-2538.
9. Xie J., Huang J., Li X., Sun S., Chen X. Iron oxide nanoparticle platform for biomedical applications. Curr Med Chem 2009, 16:1278-1294.
10. Namdeo M., Saxena S., Tankhiwale R., Bajpai M., Mohan Y.M., Bajpai S.K. Magnetic nanoparticles for drug delivery applications. J Nanosci Nanotechnol 2008, 8:3247-3271.
11. Reimer P., Balzer T. Ferucarbotran (Resovist): a new clinically approved RES-specific contrast agent for contrast-enhanced MRI of the liver: properties, clinical development, and applications. Eur Radiol 2003, 13:1266-1276.
12. Shipley H.J., Engates K.E., Guettner A.M. Study of iron oxide nanoparticles in soil for remediation of arsenic. J Nanopart Res 2010, DOI: 10.1007/s11051-010-9999-xOnline First™.
13. Bakardjieva S., Stengl V., Subrt J., Houskova V., Kalenda P. Photocatalytic efficiency of iron oxides: degradation of 4-chlorophenol. J Phys Chem Solids 2007, 68:721-724.
14. Khedr M.H., Halim K.S.A., Soliman N.K. Synthesis and photocatalytic activity of nano-sized iron oxides. Mater Lett 2009, 63:598-601.
15. Karn B., Kuiken T., Otto M. Nanotechnology and in situ remediation: a review of the benefits and potential risks. Environ Health Perspect 2009, 117:1823-1831.
16. Dickinson M., Scott T.B. The application of zero-valent iron nanoparticles for the remediation of a uranium-contaminated waste effluent. J Hazard Mater 2010, 178:171-179.
17. Li X.Q., Elliott D.W., Zhang W.X. Zero-valent iron nanoparticles for abatement of environmental pollutants: materials and engineering aspects. Crit Rev Solid State Mater Sci 2006, 31:111-122.
18. Chen S.Y., Chen W.H., Shih C.J. Heavy metal removal from wastewater using zero-valent iron nanoparticles. Water Sci Technol 2008, 58:1947-1954.
19. Zhang W.X. Nanoscale iron particles for environmental remediation: an overview. J Nanopart Res 2003, 5:323-332.
20. Mueller N.C., Nowack B. Nanoparticles for remediation: solving big problems with little particles. Elements 2010, 6:395-400.
21. Jain T.K., Reddy M.K., Morales M.A., Leslie-Pelecky D.L., Labhasetwar V. Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol Pharmaceut 2008, 5:316-327.
22. Weissleder R., Stark D.D., Engelstad B.L., Bacon B.R., Compton C.C., White D.L., et al. Superparamagnetic iron-oxide - pharmacokinetics and toxicity. Am J Roentgenol 1989, 152:167-173.
23. Stark D.D., Weissleder R., Elizondo G., Hahn P.F., Saini S., Todd L.E., et al. Superparamagnetic iron-oxide - clinical-application as a contrast agent for MR imaging of the liver. Radiology 1988, 168:297-301.
24. Strijkers G.J., Mulder W.J.M., van Tilborg G.A.F., Nicolay K. MRI contrast agents: current status and future perspectives. Anti-cancer Agents Med Chem 2007, 7.
25. Singh N., Jenkins G.J, Asadi R., Doak S.H. Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION). Nano Review 2010, 1:53-58.
26. Noori A., Parivar K., Modaresi M., Messripour M., YousefiM.H., Amiri G.R. Effect of magnetic iron oxide nanoparticles on pregnancy and testicular development of mice. Afr J Biotechnol 2011, 10:1221-1227.
27. Saunders M. Transplacental transport of nanomaterials. Wiley Interdisciplinary Reviews-Nanomed Nanobiotechnol 2009, 1:671-684.
28. Menezes V., Malek A., Keelan J.A. Nanoparticulate drug delivery in pregnancy: placental passage and fetal exposure. Curr Pharm Biotechnol 2011, 12:731-742.
29. Wigle D.T., Arbuckle T.E., Turner M.C., Berube A., Yang Q.Y., Liu S.L., et al. Epidemiologic evidence of relationships between reproductive and child health outcomes and environmental chemical contaminants. J Toxicol Environ Health-Part B-Crit Rev 2008, 11:373-517.
30. Myllynen P.K., Loughran M.J., Howard C.V., Sormunen R., Walsh A.A., Vahakangas K.H. Kinetics of gold nanoparticles in the human placenta. Reprod Toxicol 2008, 26:130-137.
31. Chu M.Q., Wu Q., Yang H., Yuan R.Q., Hou S.K., Yang Y.F., et al. Transfer of quantum dots from pregnant mice to pups across the placental barrier. Small 2010, 6:670-678.
32. Wick P., Malek A., Manser P., Meili D., Maeder-Althaus X., Diener L., et al. Barrier capacity of human placenta for nanosized materials. Environ Health Perspect 2010, 118:432-436.
33. Yamashita K., Yoshioka Y., Higashisaka K., Mimura K., Morishita Y., Nozaki M., et al. Silica and titanium dioxide nanoparticles cause pregnancy complications in mice. Nat Nanotechnol 2011, 6:321-328.
34. Takeda K., Suzuki K.I., Ishihara A., Kubo-Irie M., Fujimoto R., Tabata M., et al. Nanoparticles transferred from pregnant mice to their offspring can damage the genital and cranial nerve systems. J Health Sci 2009, 55:95-102.
35. Yoshida S., Hiyoshi K., Oshio S., Takano H., Takeda K., Ichinose T. Effects of fetal exposure to carbon nanoparticles on reproductive function in male offspring. Fertil Steril 2010, 93:1695-1699.
36. Park E.-J., Kim H., Kim Y., Park K. Effects of platinum nanoparticles on the postnatal development of mouse pups by maternal exposure. Environ Health Toxicol 2010, 25:279-286.
37. Li J., Chang X., Chen X., Gu Z., Zhao F., Chai Z., et al. Toxicity of inorganic nanomaterials in biomedical imaging. Biotechnol Adv 2014, 32:727-743.
38. 4 magnetic nanoparticles in aqueous solution. IEEE Trans Magnet 2010, 46:1541-1543.
39. Bao L., Low W.L., Jiang J., Ying J.Y. Colloidal synthesis of magnetic nanorods with tunable aspect ratios. J Mater Chem 2012, 22:7117-7120.
40. Xu Y.L., Palchoudhury S., Qin Y., Macher T., Bao Y.P. Make conjugation simple: a facile approach to integrated nanostructures. Langmuir 2012, 28:8767-8772.
41. Palchoudhury S., Xu Y.L., An W., Turner C.H., Bao Y.P. Platinum attachments on iron oxide nanoparticle surfaces. J Appl Phys 2010, 107.
42. Palchoudhury S., Xu Y.L., Goodwin J., Bao Y.P. Synthesis of multiple platinum-attached iron oxide nanoparticles. J Mater Chem 2011, 21:3966-3970.
43. Xu Y.L., Qin Y., Palchoudhury S., Bao Y.P. Water-soluble iron oxide nanoparticles with high stability and selective surface functionality. Langmuir 2011, 27:8990-8997.
44. ICH, Guideline S5 (R2): Detection of Toxicity to Reproduction for Medicinal Products & Toxicity to Male Fertility. 2005.
45. Cima G. AVMA Guidelines for the Euthanasia of Animal: 2013 Edition. J Am Vet Med Assoc 2013, 242:715-716.
46. Harisinghani M., Ross R.W., Guimaraes A.R., Weissleder R. Utility of a new bolus-injectable nanoparticle for clinical cancer staging. Neoplasia 2007, 9:1160-1170.
47. Weissleder R., Ross B.D., Rehemtulla A., Gambhir S.S. Molecular imaging: principles and practice 2010, People's Medical Publishing House, USA.
48. Fish W.W. Rapid colorimetric micromethod for the quantitation of complexed iron in biological samples. Methods Enzymol 1988, 158:357-364.
49. Webb G.N., Byrd R.A. Simultaneous differential staining of cartilage and bone in rodent fetuses - an Alcian Blue and Alizarin Red-S procedure without glacial acetic-acid. Biotechnic Histochem 1994, 69:181-185.
50. Gutaj P., Wender-Ozegowska E., Mantaj U., Zawiejska A., Brazert J. Maternal body mass index and gestational weight gain and their association with perinatal outcome in women with gestational diabetes. Ginekol Pol 2011, 82:827-833.
51. Godfrey K.M., Barker D.J. Fetal programming and adult health. Public Health Nutr 2001, 4:611-624.
52. Danielsson B.R. Maternal toxicity. Methods Mol Biol 2013, 947:311-325.
53. Khurana A., Nejadnik H., Gawande R., Lin G., Lee S., Messing S., et al. Intravenous ferumoxytol allows noninvasive MR imaging monitoring of macrophage migration into stem cell transplants. Radiology 2012, 264:803-811.