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Volumn 34, Issue 9, 2014, Pages 1330-1339

Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (suPAR) in acute liver failure

Author keywords

Acute liver failure; CD87; Monocytes; Organ failure; Prognosis; suPAR

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CD56 ANTIGEN; LIPOPOLYSACCHARIDE; MESSENGER RNA; UROKINASE RECEPTOR; BIOLOGICAL MARKER; PLAUR PROTEIN, HUMAN;

EID: 84908227402     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12512     Document Type: Article
Times cited : (49)

References (33)
  • 2
    • 84866520840 scopus 로고    scopus 로고
    • Prediction of outcome and selection of the liver transplantat candidate in acute liver failure
    • Hadem J, Strassburg CP, Manns MP. Prediction of outcome and selection of the liver transplantat candidate in acute liver failure. Front Physiol 2012; 3: 340.
    • (2012) Front Physiol , vol.3 , pp. 340
    • Hadem, J.1    Strassburg, C.P.2    Manns, M.P.3
  • 3
    • 17844365270 scopus 로고    scopus 로고
    • AASLD position paper: the management of acute liver failure
    • Polson J, Lee WM; American Association for the Study of Liver D. AASLD position paper: the management of acute liver failure. Hepatology 2005; 41: 1179-97.
    • (2005) Hepatology , vol.41 , pp. 1179-1197
    • Polson, J.1    Lee, W.M.2
  • 4
    • 66149098373 scopus 로고    scopus 로고
    • Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure
    • 64 e1.
    • Lee WM, Hynan LS, Rossaro L, et al. Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure. Gastroenterology 2009; 137: 856-64, 64 e1.
    • (2009) Gastroenterology , vol.137 , pp. 856-864
    • Lee, W.M.1    Hynan, L.S.2    Rossaro, L.3
  • 5
    • 84870877532 scopus 로고    scopus 로고
    • Functional role of monocytes and macrophages for the inflammatory response in acute liver injury
    • Zimmermann HW, Trautwein C, Tacke F. Functional role of monocytes and macrophages for the inflammatory response in acute liver injury. Front Physiol 2012; 3: 56.
    • (2012) Front Physiol , vol.3 , pp. 56
    • Zimmermann, H.W.1    Trautwein, C.2    Tacke, F.3
  • 6
    • 84866396691 scopus 로고    scopus 로고
    • Mechanisms of cell death in acute liver failure
    • Bantel H, Schulze-Osthoff K. Mechanisms of cell death in acute liver failure. Front Physiol 2012; 3: 79.
    • (2012) Front Physiol , vol.3 , pp. 79
    • Bantel, H.1    Schulze-Osthoff, K.2
  • 7
    • 84866730075 scopus 로고    scopus 로고
    • Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review
    • Backes Y, van der Sluijs KF, Mackie DP, et al. Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review. Intensive Care Med 2012; 38: 1418-28.
    • (2012) Intensive Care Med , vol.38 , pp. 1418-1428
    • Backes, Y.1    van der Sluijs, K.F.2    Mackie, D.P.3
  • 8
    • 79951557734 scopus 로고    scopus 로고
    • Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients
    • Koch A, Voigt S, Kruschinski C, et al. Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients. Crit Care 2011; 15: R63.
    • (2011) Crit Care , vol.15 , pp. R63
    • Koch, A.1    Voigt, S.2    Kruschinski, C.3
  • 9
    • 0036906177 scopus 로고    scopus 로고
    • uPAR: a versatile signalling orchestrator
    • Blasi F, Carmeliet P. uPAR: a versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002; 3: 932-43.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 932-943
    • Blasi, F.1    Carmeliet, P.2
  • 11
  • 12
    • 84856659379 scopus 로고    scopus 로고
    • Circulating soluble urokinase plasminogen activator is elevated in patients with chronic liver disease, discriminates stage and aetiology of cirrhosis and predicts prognosis
    • Zimmermann HW, Koch A, Seidler S, Trautwein C, Tacke F. Circulating soluble urokinase plasminogen activator is elevated in patients with chronic liver disease, discriminates stage and aetiology of cirrhosis and predicts prognosis. Liver Int 2011; 32: 500-9.
    • (2011) Liver Int , vol.32 , pp. 500-509
    • Zimmermann, H.W.1    Koch, A.2    Seidler, S.3    Trautwein, C.4    Tacke, F.5
  • 13
    • 84879116205 scopus 로고    scopus 로고
    • Soluble urokinase plasminogen activator receptor is compartmentally regulated in decompensated cirrhosis and indicates immune activation and short-term mortality
    • Zimmermann HW, Reuken PA, Koch A, et al. Soluble urokinase plasminogen activator receptor is compartmentally regulated in decompensated cirrhosis and indicates immune activation and short-term mortality. J Intern Med 2013; 274: 86-100.
    • (2013) J Intern Med , vol.274 , pp. 86-100
    • Zimmermann, H.W.1    Reuken, P.A.2    Koch, A.3
  • 14
    • 77956265378 scopus 로고    scopus 로고
    • Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury
    • Bechmann LP, Jochum C, Kocabayoglu P, et al. Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury. J Hepatol 2010; 53: 639-47.
    • (2010) J Hepatol , vol.53 , pp. 639-647
    • Bechmann, L.P.1    Jochum, C.2    Kocabayoglu, P.3
  • 15
    • 79959382649 scopus 로고    scopus 로고
    • Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis
    • Zimmermann HW, Seidler S, Gassler N, et al. Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis. PLoS ONE 2011; 6: e21381.
    • PLoS ONE , vol.2011 , pp. e21381
    • Zimmermann, H.W.1    Seidler, S.2    Gassler, N.3
  • 16
    • 77955096540 scopus 로고    scopus 로고
    • Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis
    • Zimmermann HW, Seidler S, Nattermann J, et al. Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis. PLoS ONE 2010; 5: e11049.
    • (2010) PLoS ONE , vol.5 , pp. e11049
    • Zimmermann, H.W.1    Seidler, S.2    Nattermann, J.3
  • 17
    • 58649089811 scopus 로고    scopus 로고
    • Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver
    • Holt AP, Haughton EL, Lalor PF, et al. Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver. Gastroenterology 2009; 136: 705-14.
    • (2009) Gastroenterology , vol.136 , pp. 705-714
    • Holt, A.P.1    Haughton, E.L.2    Lalor, P.F.3
  • 18
    • 84872159959 scopus 로고    scopus 로고
    • Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics
    • Liaskou E, Zimmermann HW, Li KK, et al. Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics. Hepatology 2013; 57: 385-98.
    • (2013) Hepatology , vol.57 , pp. 385-398
    • Liaskou, E.1    Zimmermann, H.W.2    Li, K.K.3
  • 19
    • 67650608082 scopus 로고    scopus 로고
    • Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients
    • Koch A, Gressner OA, Sanson E, Tacke F, Trautwein C. Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients. Crit Care 2009; 13: R95.
    • (2009) Crit Care , vol.13 , pp. R95
    • Koch, A.1    Gressner, O.A.2    Sanson, E.3    Tacke, F.4    Trautwein, C.5
  • 20
    • 84861338634 scopus 로고    scopus 로고
    • Etiologies and outcomes of acute liver failure in Germany
    • e2
    • Hadem J, Tacke F, Bruns T, et al. Etiologies and outcomes of acute liver failure in Germany. Clin Gastroenterol Hepatol 2012; 10: 664-9 e2.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 664-669
    • Hadem, J.1    Tacke, F.2    Bruns, T.3
  • 21
    • 0033059340 scopus 로고    scopus 로고
    • Cellular glycosylphosphatidylinositol- specific phospholipase D regulates urokinase receptor shedding and cell surface expression
    • Wilhelm OG, Wilhelm S, Escott GM, et al. Cellular glycosylphosphatidylinositol- specific phospholipase D regulates urokinase receptor shedding and cell surface expression. J Cell Physiol 1999; 180: 225-35.
    • (1999) J Cell Physiol , vol.180 , pp. 225-235
    • Wilhelm, O.G.1    Wilhelm, S.2    Escott, G.M.3
  • 22
    • 0030057250 scopus 로고    scopus 로고
    • Modulation of the receptor for urokinase-type plasminogen activator in macrophage- like U937 cells by inflammatory mediators
    • Yoshida E, Tsuchiya K, Sugiki M, et al. Modulation of the receptor for urokinase-type plasminogen activator in macrophage- like U937 cells by inflammatory mediators. Inflammation 1996; 20: 319-26.
    • (1996) Inflammation , vol.20 , pp. 319-326
    • Yoshida, E.1    Tsuchiya, K.2    Sugiki, M.3
  • 23
    • 84864942108 scopus 로고    scopus 로고
    • Plasma suPAR levels are associated with mortality, admission time, and Charlson Comorbidity Index in the acutely admitted medical patient: a prospective observational study
    • Haupt TH, Petersen J, Ellekilde G, et al. Plasma suPAR levels are associated with mortality, admission time, and Charlson Comorbidity Index in the acutely admitted medical patient: a prospective observational study. Crit Care 2012; 16: R130.
    • (2012) Crit Care , vol.16 , pp. R130
    • Haupt, T.H.1    Petersen, J.2    Ellekilde, G.3
  • 24
    • 0030782196 scopus 로고    scopus 로고
    • Structure, function and expression on blood and bone marrow cells of the urokinase- type plasminogen activator receptor, uPAR
    • Plesner T, Behrendt N, Ploug M. Structure, function and expression on blood and bone marrow cells of the urokinase- type plasminogen activator receptor, uPAR. Stem Cells 1997; 15: 398-408.
    • (1997) Stem Cells , vol.15 , pp. 398-408
    • Plesner, T.1    Behrendt, N.2    Ploug, M.3
  • 25
    • 0034625509 scopus 로고    scopus 로고
    • Shedding and cleavage of the urokinase receptor (uPAR): identification and characterisation of uPAR fragments in vitro and in vivo
    • Sidenius N, Sier CF, Blasi F. Shedding and cleavage of the urokinase receptor (uPAR): identification and characterisation of uPAR fragments in vitro and in vivo. FEBS Lett 2000; 475: 52-6.
    • (2000) FEBS Lett , vol.475 , pp. 52-56
    • Sidenius, N.1    Sier, C.F.2    Blasi, F.3
  • 26
    • 84866619398 scopus 로고    scopus 로고
    • CD14, CD16 and HLA-DR reliably identifies human monocytes and their subsets in the context of pathologically reduced HLA-DR expression by CD14(hi)/CD16(neg) monocytes: expansion of CD14(hi)/CD16(pos) and contraction of CD14(lo)/ CD16(pos) monocytes in acute liver failure
    • Abeles RD, Mcphail MJ, Sowter D, et al. CD14, CD16 and HLA-DR reliably identifies human monocytes and their subsets in the context of pathologically reduced HLA-DR expression by CD14(hi)/CD16(neg) monocytes: expansion of CD14(hi)/CD16(pos) and contraction of CD14(lo)/ CD16(pos) monocytes in acute liver failure. Cytometry A 2012; 81: 823-34.
    • (2012) Cytometry A , vol.81 , pp. 823-834
    • Abeles, R.D.1    Mcphail, M.J.2    Sowter, D.3
  • 27
    • 84864351457 scopus 로고    scopus 로고
    • Source and characterization of hepatic macrophages in acetaminophen- induced acute liver failure in humans
    • Antoniades CG, Quaglia A, Taams LS, et al. Source and characterization of hepatic macrophages in acetaminophen- induced acute liver failure in humans. Hepatology 2012; 56: 735-46.
    • (2012) Hepatology , vol.56 , pp. 735-746
    • Antoniades, C.G.1    Quaglia, A.2    Taams, L.S.3
  • 28
    • 79957858196 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor treatment ameliorates liver injury and improves survival in rats with D-galactosamine-induced acute liver failure
    • Zhang L, Kang W, Lei Y, et al. Granulocyte colony-stimulating factor treatment ameliorates liver injury and improves survival in rats with D-galactosamine-induced acute liver failure. Toxicol Lett 2011; 204: 92-9.
    • (2011) Toxicol Lett , vol.204 , pp. 92-99
    • Zhang, L.1    Kang, W.2    Lei, Y.3
  • 29
    • 84863137243 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor mobilizes CD34(+) cells and improves survival of patients with acute-on-chronic liver failure
    • e1
    • Garg V, Garg H, Khan A, et al. Granulocyte colony-stimulating factor mobilizes CD34(+) cells and improves survival of patients with acute-on-chronic liver failure. Gastroenterology 2012; 142: 505-12 e1.
    • (2012) Gastroenterology , vol.142 , pp. 505-512
    • Garg, V.1    Garg, H.2    Khan, A.3
  • 30
    • 20144382507 scopus 로고    scopus 로고
    • Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization
    • Selleri C, Montuori N, Ricci P, et al. Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization. Blood 2005; 105: 2198-205.
    • (2005) Blood , vol.105 , pp. 2198-2205
    • Selleri, C.1    Montuori, N.2    Ricci, P.3
  • 31
    • 84878280950 scopus 로고    scopus 로고
    • Urokinase plasminogen activator receptor: a functional integrator of extracellular proteolysis, cell adhesion, and signal transduction
    • Ferraris GM, Sidenius N. Urokinase plasminogen activator receptor: a functional integrator of extracellular proteolysis, cell adhesion, and signal transduction. Semin Thromb Hemost 2013; 39: 347-55.
    • (2013) Semin Thromb Hemost , vol.39 , pp. 347-355
    • Ferraris, G.M.1    Sidenius, N.2
  • 32
    • 79961132981 scopus 로고    scopus 로고
    • Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
    • Wei C, El Hindi S, Li J, et al. Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med 2011; 17: 952-60.
    • (2011) Nat Med , vol.17 , pp. 952-960
    • Wei, C.1    El Hindi, S.2    Li, J.3
  • 33
    • 84875661389 scopus 로고    scopus 로고
    • Serum sodium based modification of the MELD does not improve prediction of outcome in acute liver failure
    • Manka P, Bechmann LP, Tacke F, et al. Serum sodium based modification of the MELD does not improve prediction of outcome in acute liver failure. BMC Gastroenterol 2013; 13: 58.
    • (2013) BMC Gastroenterol , vol.13 , pp. 58
    • Manka, P.1    Bechmann, L.P.2    Tacke, F.3


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