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Volumn 15, Issue 11, 2014, Pages 850.e11-850.e15

Impact of Polypharmacy on Occurrence of Delirium in Elderly Emergency Patients

Author keywords

Delirium; Drug induced delirium; Elderly; Geriatrics; Polypharmacy

Indexed keywords

BENZAMIDE; BENZAMIDE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BUTYROPHENONE DERIVATIVE; CIPROFLOXACIN; DOPAMINE RECEPTOR STIMULATING AGENT; HISTAMINE H1 RECEPTOR ANTAGONIST; HYDROXYZINE; HYPNOTIC AGENT; LEVODOPA; LEVOFLOXACIN; LITHIUM; MEPROBAMATE; METHYLPREDNISOLONE; MORPHINE; MOXIFLOXACIN; NEUROLEPTIC AGENT; NORFLOXACIN; OFLOXACIN; OPIATE; PHENOTHIAZINE DERIVATIVE; PREDNISOLONE; PREDNISONE; QUINOLONE DERIVATIVE; THIOXANTHENE DERIVATIVE; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; ZOLPIDEM; ZOPICLONE;

EID: 84908224608     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2014.08.012     Document Type: Article
Times cited : (103)

References (47)
  • 1
    • 33745403310 scopus 로고    scopus 로고
    • Occurrence and outcome of delirium in medical in-patient: A systematic literature review
    • Siddiqi N., Horne A.O., House A.O., Holmes J.D. Occurrence and outcome of delirium in medical in-patient: A systematic literature review. Age Ageing 2006, 35:350-364.
    • (2006) Age Ageing , vol.35 , pp. 350-364
    • Siddiqi, N.1    Horne, A.O.2    House, A.O.3    Holmes, J.D.4
  • 2
    • 34247569324 scopus 로고    scopus 로고
    • Delirium in older people
    • Young J., Inouye S.K. Delirium in older people. BMJ 2007, 334:842-846.
    • (2007) BMJ , vol.334 , pp. 842-846
    • Young, J.1    Inouye, S.K.2
  • 4
    • 0031932070 scopus 로고    scopus 로고
    • Delirium risk factors in elderly hospitalized patients
    • Elie M., Cole M.G., Primeau F.J., et al. Delirium risk factors in elderly hospitalized patients. JGen Intern Med 1998, 13:204-212.
    • (1998) JGen Intern Med , vol.13 , pp. 204-212
    • Elie, M.1    Cole, M.G.2    Primeau, F.J.3
  • 5
    • 77952965251 scopus 로고    scopus 로고
    • Delirium in the emergency department: An independent predictor of death within 6 months
    • Han J.H., Shintani A., Eden S., et al. Delirium in the emergency department: An independent predictor of death within 6 months. Ann Emerg Med 2010, 56:244-252.
    • (2010) Ann Emerg Med , vol.56 , pp. 244-252
    • Han, J.H.1    Shintani, A.2    Eden, S.3
  • 6
    • 77954343606 scopus 로고    scopus 로고
    • Hospital use, institutionalisation and mortality associated with delirium
    • Eeles E.M., Hubbard R.E., White S.V., et al. Hospital use, institutionalisation and mortality associated with delirium. Age Ageing 2010, 39:470-475.
    • (2010) Age Ageing , vol.39 , pp. 470-475
    • Eeles, E.M.1    Hubbard, R.E.2    White, S.V.3
  • 7
    • 77954964464 scopus 로고    scopus 로고
    • Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: A meta-analysis
    • Witlox J., Eurelings L.S., de Jonghe J.F., et al. Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: A meta-analysis. JAMA 2010, 304:443-451.
    • (2010) JAMA , vol.304 , pp. 443-451
    • Witlox, J.1    Eurelings, L.S.2    de Jonghe, J.F.3
  • 8
    • 0242576066 scopus 로고    scopus 로고
    • Does delirium increase hospital stay?
    • McCusker J., Cole M.G., Dendukuri N., et al. Does delirium increase hospital stay?. JAm Geriatr Soc 2003, 51:1539-1546.
    • (2003) JAm Geriatr Soc , vol.51 , pp. 1539-1546
    • McCusker, J.1    Cole, M.G.2    Dendukuri, N.3
  • 9
    • 67649389937 scopus 로고    scopus 로고
    • Delirium accelerates cognitive decline in Alzheimer disease
    • Fong T.G., Jones R.N., Shi P., et al. Delirium accelerates cognitive decline in Alzheimer disease. Neurology 2009, 72:1570-1575.
    • (2009) Neurology , vol.72 , pp. 1570-1575
    • Fong, T.G.1    Jones, R.N.2    Shi, P.3
  • 10
    • 67649210721 scopus 로고    scopus 로고
    • Delirium in elderly adults: Diagnosis, prevention and treatment
    • Fong T.G., Tulebaev S.R., Inouye S.K. Delirium in elderly adults: Diagnosis, prevention and treatment. Nat Rev Neurol 2009, 5:210-220.
    • (2009) Nat Rev Neurol , vol.5 , pp. 210-220
    • Fong, T.G.1    Tulebaev, S.R.2    Inouye, S.K.3
  • 11
    • 3242675065 scopus 로고    scopus 로고
    • An approach to drug induced delirium in the elderly
    • Alagiakrishnan K., Wiens C.A. An approach to drug induced delirium in the elderly. Postgrad Med J 2004, 80:388-393.
    • (2004) Postgrad Med J , vol.80 , pp. 388-393
    • Alagiakrishnan, K.1    Wiens, C.A.2
  • 12
    • 0034920302 scopus 로고    scopus 로고
    • Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients
    • Han L., McCusker J., Cole M., et al. Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients. Arch Intern Med 2001, 161:1099-1105.
    • (2001) Arch Intern Med , vol.161 , pp. 1099-1105
    • Han, L.1    McCusker, J.2    Cole, M.3
  • 13
    • 73849151729 scopus 로고    scopus 로고
    • Drug-induced, dementia-associated and nondementia, non-drug delirium hospitalizations in the United States, 1998-2005: An analysis of the national inpatient sample
    • Lin R.Y., Heacok L.C., Fogel J.F. Drug-induced, dementia-associated and nondementia, non-drug delirium hospitalizations in the United States, 1998-2005: An analysis of the national inpatient sample. Drugs Aging 2010, 27:51-61.
    • (2010) Drugs Aging , vol.27 , pp. 51-61
    • Lin, R.Y.1    Heacok, L.C.2    Fogel, J.F.3
  • 14
    • 0029917496 scopus 로고    scopus 로고
    • Precipiting factors for delirium in hospitalised elderly persons. Predictive model and interrelationship with baseline vulnerability
    • Inouye S.K., Charpentier P. Precipiting factors for delirium in hospitalised elderly persons. Predictive model and interrelationship with baseline vulnerability. JAMA 1996, 275:852-857.
    • (1996) JAMA , vol.275 , pp. 852-857
    • Inouye, S.K.1    Charpentier, P.2
  • 15
    • 0035092435 scopus 로고    scopus 로고
    • Suboptimal prescribing in older inpatients and outpatients
    • Hanlon J.T., Schmader K.E., Ruby C.M., et al. Suboptimal prescribing in older inpatients and outpatients. JAm Geriatr Soc 2001, 49:200-209.
    • (2001) JAm Geriatr Soc , vol.49 , pp. 200-209
    • Hanlon, J.T.1    Schmader, K.E.2    Ruby, C.M.3
  • 17
    • 79955678615 scopus 로고    scopus 로고
    • Criteria for drug selection in frail elderly persons
    • Huisman-Baron M., van der Veen L., Jansen P.A., et al. Criteria for drug selection in frail elderly persons. Drugs Aging 2011, 28:391-402.
    • (2011) Drugs Aging , vol.28 , pp. 391-402
    • Huisman-Baron, M.1    van der Veen, L.2    Jansen, P.A.3
  • 19
    • 33750081453 scopus 로고    scopus 로고
    • Epidemiology of medication-related adverse events in nursing homes
    • Handler S.M., Wright R.M., Ruby C.M., et al. Epidemiology of medication-related adverse events in nursing homes. Am J Geriatr Pharmacother 2006, 4:264-272.
    • (2006) Am J Geriatr Pharmacother , vol.4 , pp. 264-272
    • Handler, S.M.1    Wright, R.M.2    Ruby, C.M.3
  • 20
    • 77649260624 scopus 로고    scopus 로고
    • Polypharmacy in nursing home residents in the United States: Results of the 2004 National Nursing Home Survey
    • Dwyer L.L., Han B., Woodwell D.A., et al. Polypharmacy in nursing home residents in the United States: Results of the 2004 National Nursing Home Survey. Am J Geriatr Pharmacother 2010, 8:63-72.
    • (2010) Am J Geriatr Pharmacother , vol.8 , pp. 63-72
    • Dwyer, L.L.1    Han, B.2    Woodwell, D.A.3
  • 21
    • 14044252070 scopus 로고    scopus 로고
    • Potential drug-disease interactionsin frail, hospitalized elderly veterans
    • Lindblad C.I., Artz M.B., Pieper C.F., et al. Potential drug-disease interactionsin frail, hospitalized elderly veterans. Ann Pharmacother 2005, 39:412-417.
    • (2005) Ann Pharmacother , vol.39 , pp. 412-417
    • Lindblad, C.I.1    Artz, M.B.2    Pieper, C.F.3
  • 22
    • 0033755482 scopus 로고    scopus 로고
    • Drug-drug interactions in medical patients: Effects of in-hospital treatment and relation to multiple drug use
    • Kohler G.I., Bode-Boger S.M., Busse R., et al. Drug-drug interactions in medical patients: Effects of in-hospital treatment and relation to multiple drug use. Int J Clin Pharmacol Ther 2000, 38:504-513.
    • (2000) Int J Clin Pharmacol Ther , vol.38 , pp. 504-513
    • Kohler, G.I.1    Bode-Boger, S.M.2    Busse, R.3
  • 23
    • 34547813703 scopus 로고    scopus 로고
    • Potential drug interactions during a three-decade study period: A cross-sectional study of a prescription register
    • Astrand E., Astrand B., Antonov K., et al. Potential drug interactions during a three-decade study period: A cross-sectional study of a prescription register. Eur J Clin Pharmacol 2007, 63:851-859.
    • (2007) Eur J Clin Pharmacol , vol.63 , pp. 851-859
    • Astrand, E.1    Astrand, B.2    Antonov, K.3
  • 24
    • 34748920945 scopus 로고    scopus 로고
    • The relationship between number of drugs and potentialdrug-drug interactions in the elderly: A study of over 600,000 elderly patients from the Swedish Prescribed Drug Register
    • Johnell K., Klarin I. The relationship between number of drugs and potentialdrug-drug interactions in the elderly: A study of over 600,000 elderly patients from the Swedish Prescribed Drug Register. Drug Saf 2007, 30:911-918.
    • (2007) Drug Saf , vol.30 , pp. 911-918
    • Johnell, K.1    Klarin, I.2
  • 25
    • 52649138472 scopus 로고    scopus 로고
    • Frequency of and risk factors for preventable medication-related hospital admission in The Netherlands
    • HARM Study Group
    • Leendertse A.J., Egberts A.C., Stoker L.J., et al. Frequency of and risk factors for preventable medication-related hospital admission in The Netherlands. Arch Intern Med 2008, 168:1890-1896. HARM Study Group.
    • (2008) Arch Intern Med , vol.168 , pp. 1890-1896
    • Leendertse, A.J.1    Egberts, A.C.2    Stoker, L.J.3
  • 26
    • 33846042587 scopus 로고    scopus 로고
    • Is inappropriate medication use a major cause of adverse drug reactions in the elderly?
    • Laroche M.L., Charmes J.P., Nouaille Y., et al. Is inappropriate medication use a major cause of adverse drug reactions in the elderly?. Br J Clin Pharmacol 2007, 63:177-186.
    • (2007) Br J Clin Pharmacol , vol.63 , pp. 177-186
    • Laroche, M.L.1    Charmes, J.P.2    Nouaille, Y.3
  • 27
    • 20044362718 scopus 로고    scopus 로고
    • Potentially inappropriate medication use among elderly home care patients in Europe
    • Fialová D., Topinkova E., Gambassi G., et al. Potentially inappropriate medication use among elderly home care patients in Europe. JAMA 2005, 293:1348-1358.
    • (2005) JAMA , vol.293 , pp. 1348-1358
    • Fialová, D.1    Topinkova, E.2    Gambassi, G.3
  • 28
    • 43249127769 scopus 로고    scopus 로고
    • The Confusion Assessment Method: A systematic review of current usage
    • Wei L.A., Fearing M.A., Sternberg E.J., et al. The Confusion Assessment Method: A systematic review of current usage. JAm Geriatr Soc 2008, 56:823-830.
    • (2008) JAm Geriatr Soc , vol.56 , pp. 823-830
    • Wei, L.A.1    Fearing, M.A.2    Sternberg, E.J.3
  • 29
    • 33846110894 scopus 로고    scopus 로고
    • Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems
    • Viktil K.K., Blix H.S., Moger T.A., et al. Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems. Br J Clin Pharmacol 2007, 63:187-195.
    • (2007) Br J Clin Pharmacol , vol.63 , pp. 187-195
    • Viktil, K.K.1    Blix, H.S.2    Moger, T.A.3
  • 30
    • 0141538307 scopus 로고    scopus 로고
    • Reduction of polypharmacy in the elderly: A systemic review of the role of the pharmacist
    • Rollason V., Vogt N. Reduction of polypharmacy in the elderly: A systemic review of the role of the pharmacist. Drugs Aging 2003, 20:817-832.
    • (2003) Drugs Aging , vol.20 , pp. 817-832
    • Rollason, V.1    Vogt, N.2
  • 31
    • 12144288693 scopus 로고    scopus 로고
    • Asystematic literature review of factors affecting outcome in older medical patients admitted to hospital
    • Campbell S.E., Seymour D.G., Primrose W.R. Asystematic literature review of factors affecting outcome in older medical patients admitted to hospital. Age Ageing 2004, 33:110-115.
    • (2004) Age Ageing , vol.33 , pp. 110-115
    • Campbell, S.E.1    Seymour, D.G.2    Primrose, W.R.3
  • 32
    • 0037408404 scopus 로고    scopus 로고
    • The effect of mental status screening on the care of elderly emergency department patients
    • Hustey F.M., Meldon S.W., Smith M.D., et al. The effect of mental status screening on the care of elderly emergency department patients. Ann Emerg Med 2003, 41:678-684.
    • (2003) Ann Emerg Med , vol.41 , pp. 678-684
    • Hustey, F.M.1    Meldon, S.W.2    Smith, M.D.3
  • 33
    • 62249209537 scopus 로고    scopus 로고
    • Delirium in older emergency department patients: Recognition, risk factors, and psychomotor subtypes
    • Han J.H., Zimmerman E.E., Cutler N., et al. Delirium in older emergency department patients: Recognition, risk factors, and psychomotor subtypes. Acad Emerg Med 2009, 16:193-200.
    • (2009) Acad Emerg Med , vol.16 , pp. 193-200
    • Han, J.H.1    Zimmerman, E.E.2    Cutler, N.3
  • 34
    • 77955761916 scopus 로고    scopus 로고
    • Does this patient have delirium? Value of bedside instruments
    • Wong C.L., Holroyd-Leduc J., Simel D.L., et al. Does this patient have delirium? Value of bedside instruments. JAMA 2010, 304:779-786.
    • (2010) JAMA , vol.304 , pp. 779-786
    • Wong, C.L.1    Holroyd-Leduc, J.2    Simel, D.L.3
  • 35
    • 67749103704 scopus 로고    scopus 로고
    • Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: The 3-city study
    • Carrière I., Fourrier-Reglat A., Dartigues J.F., et al. Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: The 3-city study. Arch Intern Med 2009, 169:1317-1324.
    • (2009) Arch Intern Med , vol.169 , pp. 1317-1324
    • Carrière, I.1    Fourrier-Reglat, A.2    Dartigues, J.F.3
  • 36
    • 28044462641 scopus 로고    scopus 로고
    • Sedative hypnotics in older people with insomnia: Meta-analysis of risks and benefits
    • Glass J., Lanctôt K.L., Herrmann N., et al. Sedative hypnotics in older people with insomnia: Meta-analysis of risks and benefits. BMJ 2005, 331:1169.
    • (2005) BMJ , vol.331 , pp. 1169
    • Glass, J.1    Lanctôt, K.L.2    Herrmann, N.3
  • 37
    • 78650322801 scopus 로고    scopus 로고
    • Which medications to avoid in people at risk of delirium: A systematic review
    • Clegg A., Young J.B. Which medications to avoid in people at risk of delirium: A systematic review. Age Ageing 2011, 40:23-29.
    • (2011) Age Ageing , vol.40 , pp. 23-29
    • Clegg, A.1    Young, J.B.2
  • 38
    • 77949366024 scopus 로고    scopus 로고
    • Safety considerations of fluoroquinolones in the elderly: An update
    • Stahlmann R., Lode H. Safety considerations of fluoroquinolones in the elderly: An update. Drugs Aging 2010, 27:193-209.
    • (2010) Drugs Aging , vol.27 , pp. 193-209
    • Stahlmann, R.1    Lode, H.2
  • 39
    • 1642580682 scopus 로고    scopus 로고
    • Measurement, correlates, and health outcomes of medication adherence among seniors
    • Vik S.A., Maxwell C.J., Hogan D.B. Measurement, correlates, and health outcomes of medication adherence among seniors. Ann Pharmacother 2004, 38:303-312.
    • (2004) Ann Pharmacother , vol.38 , pp. 303-312
    • Vik, S.A.1    Maxwell, C.J.2    Hogan, D.B.3
  • 40
    • 0025836757 scopus 로고
    • Is age an independent risk factor of adverse drug reactions in hospitalized medical patients?
    • Carbonin P., Pahor M., Bernabei R., et al. Is age an independent risk factor of adverse drug reactions in hospitalized medical patients?. JAm Geriatr Soc 1991, 39:1093-1099.
    • (1991) JAm Geriatr Soc , vol.39 , pp. 1093-1099
    • Carbonin, P.1    Pahor, M.2    Bernabei, R.3
  • 41
    • 0034926440 scopus 로고    scopus 로고
    • Risk factors for adverse drug events among nursing home residents
    • Field T.S., Gurwitz J.H., Avorn J., et al. Risk factors for adverse drug events among nursing home residents. Arch Intern Med 2001, 161:1629-1634.
    • (2001) Arch Intern Med , vol.161 , pp. 1629-1634
    • Field, T.S.1    Gurwitz, J.H.2    Avorn, J.3
  • 42
    • 0036904903 scopus 로고    scopus 로고
    • Adverse drug reactions as cause of hospital admissions: Results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    • Onder G., Pedone C., Landi F., et al. Adverse drug reactions as cause of hospital admissions: Results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). JAm Geriatr Soc 2002, 50:1962-1968.
    • (2002) JAm Geriatr Soc , vol.50 , pp. 1962-1968
    • Onder, G.1    Pedone, C.2    Landi, F.3
  • 43
    • 79953718475 scopus 로고    scopus 로고
    • Asystematic review of barriers to medication adherence in the elderly: Looking beyond cost and regimen complexity
    • Gellad W.F., Grenard J.L., Marcum Z.A. Asystematic review of barriers to medication adherence in the elderly: Looking beyond cost and regimen complexity. Am J Geriatr Pharmacother 2011, 9:11-23.
    • (2011) Am J Geriatr Pharmacother , vol.9 , pp. 11-23
    • Gellad, W.F.1    Grenard, J.L.2    Marcum, Z.A.3
  • 44
    • 40949093156 scopus 로고    scopus 로고
    • The 6 and 12 month outcomes of older medical inpatients who recover from delirium
    • Cole M.G., You Y., McCusker J., et al. The 6 and 12 month outcomes of older medical inpatients who recover from delirium. Int J Geriatr Psychiatry 2008, 23:301-307.
    • (2008) Int J Geriatr Psychiatry , vol.23 , pp. 301-307
    • Cole, M.G.1    You, Y.2    McCusker, J.3
  • 45
    • 77954574142 scopus 로고    scopus 로고
    • Development and validation of a score to assess risk of adverse drug reactions among in-hospital patients 65 years or older: The GerontoNet ADR risk score
    • Onder G., Petrovic M., Tangiisuran B., et al. Development and validation of a score to assess risk of adverse drug reactions among in-hospital patients 65 years or older: The GerontoNet ADR risk score. Arch Intern Med 2010, 170:1142-1148.
    • (2010) Arch Intern Med , vol.170 , pp. 1142-1148
    • Onder, G.1    Petrovic, M.2    Tangiisuran, B.3
  • 46
    • 84912534140 scopus 로고    scopus 로고
    • An educational intervention on drug use in nursing homes improves health outcomes resource utilization and reduces inappropriate drug prescription
    • In press
    • García-Gollarte F., Baleriola-Júlvez J., Ferrero-López I., et al. An educational intervention on drug use in nursing homes improves health outcomes resource utilization and reduces inappropriate drug prescription. JAm Med Dir Assoc 2014, In press.
    • (2014) JAm Med Dir Assoc
    • García-Gollarte, F.1    Baleriola-Júlvez, J.2    Ferrero-López, I.3
  • 47
    • 77954933596 scopus 로고    scopus 로고
    • Assessment of a safety enhancement to the hospital medication reconciliation process for elderly patients
    • Gizzi L.A., Slain D., Hare J.T., et al. Assessment of a safety enhancement to the hospital medication reconciliation process for elderly patients. Am J Geriatr Pharmacother 2010, 8:127-135.
    • (2010) Am J Geriatr Pharmacother , vol.8 , pp. 127-135
    • Gizzi, L.A.1    Slain, D.2    Hare, J.T.3


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