Targeting cancer cells with reactive oxygen and nitrogen species generated by atmospheric-pressure air plasma

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Ahn, Hak Jun ^a   Kim, Kang Il ^a   Hoan, Nguyen Ngoc ^a   Kim, Churl Ho ^b   Moon, Eunpyo ^a   Choi, Kyeong Sook ^b   Yang, Sang Sik ^a   Lee, Jong Soo ^a  

^a Ajou University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AIR PLASMA; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE 14; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ATMOSPHERIC PRESSURE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; MEDICAL DEVICE; MICROPLASMA JET SYSTEM; MITOCHONDRIAL MEMBRANE POTENTIAL; SIGNAL TRANSDUCTION;

AIR; ANTIOXIDANTS; APOPTOSIS; ATMOSPHERIC PRESSURE; ENZYME ACTIVATION; EXTRACELLULAR SPACE; HELA CELLS; HUMANS; INTRACELLULAR SPACE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEOPLASMS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLASMA GASES; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SPECTRUM ANALYSIS;

EID: 84908216137     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086173     Document Type: Article

References (40)

1. Kalghatgi S, Kelly CM, Cerchar E, Torabi B, Alekseev O, et al. (2011) Effects of non-thermal plasma on mammalian cells. PLoS one 6: e16270.
2. Ahn HJ, Kim KI, Kim G, Moon E, Yang SS, et al. (2011) Atmospheric-pressure plasma jet induces apoptosis involving mitochondria via generation of free radicals. PLoS one 6: e28154.
3. Hong YF, Kang JG, Lee HY, Uhm HS, Moon E, et al. (2009) Sterilization effect of atmospheric plasma on Escherichia coli and Bacillus subtilis endospores. Lett Appl Microbiol 48: 33-7.
4. Rupf S, Lehmann A, Hannig M, Schäfer B, Schubert A, et al. (2010) Killing of adherent oral microbes by a non-thermal atmospheric plasma jet. J Med Microbiol 59: 206-12.
5. Yamamori T, Yasui H, Yamazumi M, Wada Y, Nakamura Y, et al. (2012) Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint. Free Radic Biol Med 15: 260-70.
6. Mittler R, Vanderauwera S, Suzuki N, Miller G, Tognetti VB, et al. (2011) ROS signaling: the new wave? Trends Plant Sci 16: 300-9.
7. Finkel T (2011) Signal transduction by reactive oxygen species. J Cell Biol 194: 7-15. Review.
8. Bae YS, Oh H, Rhee SG, Yoo YD (2011) Regulation of reactive oxygen species generation in cell signaling. Mol Cells 32: 491-509.
9. Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103: 239-52.
10. Torres M (2003) Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 8: d369-91.
11. Tournier C, Hess P, Yang DD, Xu J, Turner TK, et al. (2000) Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 288: 870-4. (Pubitemid 30257738)
12. Aoki H, Kang PM, Hampe J, Yoshimura K, Noma T, et al. (2002) Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes. J Biol Chem 277: 10244-50. (Pubitemid 34968139)
13. Putcha GV, Le S, Frank S, Besirli GG, Clark K, et al. 2003) JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 38: 99-914.
14. Kim GC, Kim GJ, Park SR, Jeon SM, Seo HJ, et al. (2009) Air plasma coupled with antibody-conjugated nanoparticles: a new weapon against cancer. J Phys D:Appl Phys 42: 032005.
15. Kim GJ, Kim W, Kim KT, Lee JK (2010) DNA damage and mitochondria dysfunction in cell apoptosis induced by nonthermal air plasma. Appl Phys Lett 96: 021502.
16. Kim K, Kim G, Hong YC, Yang SS (2010) A cold micro plasma jet device suitable for bio-medical applications. Microelectronic Engineering 87: 1177-1180.
17. Lee HJ, Shon CH, Kim YS, Kim S, Kim GC, et al. (2009) Degradation of adhesion molecules of G361 melanoma cells by a non-thermal atmospheric pressure microplasma. New J Phys 11: 115026.
18. Zhang X, Li M, Zhou R, Feng K, Yang S (2008) Ablation of liver cancer cells in vitro by a plasma needle. Appl Phys Lett 93: 021502.
19. Fridman G, Shereshevsky A, Jost MM, Brooks AD, Fridman A, et al. (2007) Floating Electrode Dielectric Barrier Discharge Plasma in Air Promoting Apoptotic Behavior in Melanoma Skin Cancer Cell Lines. Plasma Chem Plasma Process 27: 163-176. (Pubitemid 46501665)
20. Kim K, Choi JD, Hong YC, Kim G, Noh EJ, et al. (2011) Atmospheric-pressure plasma-jet from micronozzle array and its biological effects on living cells for cancer therapy. Appl Phys Lett 98: 073701.
21. Kim K, Kim G, Oh Y, Park TG, Han DC, et al. (2012) Simple Atmospheric-Pressure Nonthermal Plasma-Jet System for Poly(dimethylsiloxane) Bonding Process. Japanese Journal of Applied Physics 51: 06FL15-1.
22. Dobrynin D, Fridman A, Yu A (2012) Reactive oxygen and nitrogen species production and delivery into liqid media by microsecond thermal spark-discharge plasma jet. IEEE T PLASMA SCI 40: 2163-2171.
23. Köritzer J, Boxhammer V, Schäfer A, Shimizu T, Klämpfl TG, et al. (2013) Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma. 2013. PLoS one 8: e64498.
24. Franco R, Panayiotidis MI, Cidlowski JA (2007) Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation. J Biol Chem 282: 30452-65. (Pubitemid 350035221)
25. Skulachev VP (2006) Bioenergetic aspects of apoptosis, necrosis and mitoptosis. Apoptosis 11: 473-85. Review.
26. Cook SA, Sugden PH, Clerk A (1999) Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. Circ Res 85: 940-9. (Pubitemid 29534169)
27. Lindsay J, Esposti MD, Gilmore AP (2011) Bcl-2 proteins and mitochondria - specificity in membrane targeting for death. Biochim Biophys Acta 1813: 532-9.
28. Chalah A, Khosravi-Far R (2008) The mitochondrial death pathway. Adv Exp Med Biol 615: 25-45.
29. Brenner D, Mak TW (2009) Mitochondrial cell death effectors. 2009. Curr Opin Cell Biol 21: 871-7.
30. Kaufmann T, Strasser A, Jost PJ (2012) Fas death receptor signalling: roles of Bid and XIAP. Cell Death Differ 19: 42-50. Review.
31. Zorov DB, Juhaszova M, Sollott SJ (2006) Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta 1757: 509-517.
32. Laurent A, Nicco C, Chéreau C, Goulvestre C, Alexandre J et al. (2005) Controlling tumor growth by modulating endogenous production of reactive oxygen species. Cancer Res 65: 948-56. (Pubitemid 40216456)
33. Arjunan KP, Friedman G, Fridman A, Clyne AM (2012) Non-thermal dielectric barrier discharge plasma induces angiogenesis through reactive oxygen speciesJ R Soc Interface 9: 147-57.
34. Trachootham D, Alexandre J, Huang P (2009) Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 8: 579-91. Review.
35. Kong AN, Yu R, Chen C, Mandlekar S, Primiano T (2000) Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis. Arch Pharm Res 23: 1-16. Review.
36. Kim SY, Kim SJ, Kim BJ, Rah SY, Chung SM, et al. (2006) Doxorubicin-induced reactive oxygen species generation and intracellular Ca 2+ increase are reciprocally modulated in rat cardiomyocytes. Exp Mol Med 38: 535-45.
37. Marletta MA (1989) Nitric oxide: biosynthesis and biological significance. 1989. Trends Biochem Sci 14: 488-92. (Pubitemid 19284346)
38. Sun J, Zhang X, Broderick M, Fein H (2003) Measurement of Nitric Oxide Production in Biological Systems by Using Griess Reaction Assay. Sensors 3: 276-284. (Pubitemid 40643539)
39. Oleinik NV, Krupenko NI, Krupenko SA (2007) Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway. Oncogene 26: 7222-30. (Pubitemid 350085318)
40. Mikule K, Delaval B, Kaldis P, Jurcyzk A, Hergert P, et al. (2007) Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest. Nat Cell Biol 9: 160-70. (Pubitemid 46420858)