Insights into the mechanisms of membrane curvature and vesicle scission by the small GTPase Sar1 in the early secretory pathway

Journal of Molecular Biology

Volumn 426, Issue 22, 2014, Pages 3811-3826

  Hariri, Hanaa ^a   Bhattacharya, Nilakshee ^a   Johnson, Kerri ^a   Noble, Alex J ^b   Stagg, Scott M ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

^b Florida State University   (United States)

Author keywords

ADE model; dimerization; membrane scission; N terminal helix; Sar1 lattice

Indexed keywords

COAT PROTEIN COMPLEX II; DIMER; GUANOSINE TRIPHOSPHATE DERIVATIVE; SAR1 PROTEIN; TRANSFORMING PROTEIN; UNCLASSIFIED DRUG; GUANOSINE TRIPHOSPHATE; LIPOSOME; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; SAR1B PROTEIN, HUMAN;

ARTICLE; COATED VESICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DENSITY GRADIENT CENTRIFUGATION; DIMERIZATION; ELECTRON MICROSCOPY; ELECTRON TOMOGRAPHY; ENDOPLASMIC RETICULUM; FOURIER TRANSFORMATION; GIANT UNILAMELLAR VESICLE; HUMAN; LIPID MEMBRANE; MEMBRANE BINDING; MEMBRANE CURVATURE; MEMBRANE STRUCTURE; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; SECRETORY PATHWAY; TRANSMISSION ELECTRON MICROSCOPY; CELL MEMBRANE; CHEMISTRY; GENETICS; HYDROLYSIS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN MULTIMERIZATION;

CELL MEMBRANE; COP-COATED VESICLES; ENDOPLASMIC RETICULUM; GUANOSINE TRIPHOSPHATE; HUMANS; HYDROLYSIS; LIPOSOMES; MONOMERIC GTP-BINDING PROTEINS; MUTATION; PROTEIN MULTIMERIZATION; SECRETORY PATHWAY;

EID: 84908199281     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.08.023     Document Type: Article

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