Anti-proliferative activities of sinigrin on carcinogen-induced hepatotoxicity in rats

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Jie, Meng ^a   Cheung, Wan Man ^a   Yu, Vivian ^a   Zhou, Yanling ^a   Tong, Pak Ho ^a   Ho, John W S ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE; CELL NUCLEUS ANTIGEN; DOXORUBICIN; PROLIFERATION CELL NUCLEAR ANTIGEN; PROTEIN BAX; PROTEIN MDM2; PROTEIN P53; SINIGRIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CARCINOGEN; GLUCOSINOLATE; MESSENGER RNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CANCER INHIBITION; CELL CYCLE G0 PHASE; CONTROLLED STUDY; DOWN REGULATION; DRUG DOSE COMPARISON; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; LIVER FUNCTION; LIVER TOXICITY; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; TREATMENT DURATION; TUMOR VOLUME; UPREGULATION; ANIMAL; CELL PROLIFERATION; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIVER; LIVER TUMOR; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

RATTUS;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOGENS; CELL LINE, TUMOR; CELL PROLIFERATION; G0 PHASE; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSINOLATES; HUMANS; LIVER; LIVER NEOPLASMS; MALE; PROTO-ONCOGENE PROTEINS C-MDM2; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84908179522     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110145     Document Type: Article

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