Depletion of Foxp3+ T cells abrogates tolerance of skin and heart allografts in murine mixed chimeras without the loss of mixed chimerism

American Journal of Transplantation

Volumn 14, Issue 10, 2014, Pages 2263-2274

  Shinoda, K ^a   Akiyoshi, T ^a   Chase, C M ^a   Farkash, E A ^a   Ndishabandi, D K ^a   Raczek, C M ^a   Sebastian, D P ^a   Della Pelle, P ^a   Russell, P S ^a,b   Madsen, J C ^a,b   Colvin, R B ^a,b   Alessandrini, A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Basic (laboratory) research; bone marrow; cardiology; heart transplantation; hematopoietic stem cell transplantation; immunobiology; major histocompatibility complex (MHC); science; tolerance: chimerism; tolerance: mechanisms

Indexed keywords

DIPHTHERIA TOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL INFILTRATION; CELL LINEAGE; CHIMERA; CONTROLLED STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLOW CYTOMETRY; HEART TRANSPLANTATION; HEMATOPOIETIC CELL; IMMUNOHISTOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL LYMPHOCYTE; REGULATORY T LYMPHOCYTE; SKIN ALLOGRAFT; T CELL DEPLETION; TRANSPLANTATION TOLERANCE; ANIMAL; ENZYME LINKED IMMUNOSORBENT ASSAY; GRAFT REJECTION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LYMPHOCYTE DEPLETION; SKIN TRANSPLANTATION; T LYMPHOCYTE;

ANIMALS; CHIMERA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GRAFT REJECTION; HEART TRANSPLANTATION; IMMUNE TOLERANCE; LYMPHOCYTE DEPLETION; MICE; SKIN TRANSPLANTATION; T-LYMPHOCYTES;

EID: 84908151258     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12851     Document Type: Article

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