Assessment of disintegrant efficacy with fractal dimensions from real-time MRI

International Journal of Pharmaceutics

Volumn 475, Issue 1, 2014, Pages 605-612

  Quodbach, Julian ^a   Moussavi, Amir ^b   Tammer, Roland ^b,c   Frahm, Jens ^b,c   Kleinebudde, Peter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Biomedizinische NMR Forschungs GmbH   (Germany)

^c Cluster of Excellence Nanoscale Microscopy and Molecular Physiology of the Brain   (Germany)

Author keywords

Formulation; Polymers; Superdisintegrants; Tablet disintegration; Visualization

Indexed keywords

CALCIUM PHOSPHATE; CROSCARMELLOSE SODIUM; CROSPOVIDONE; DI CAFOS C92 14; DISINTEGRATING AGENT; KYRON T 314; POLACRILIN; STARCH GLYCOLATE SODIUM; UNCLASSIFIED DRUG; CARBOXYMETHYLCELLULOSE; EXCIPIENT; POVIDONE; RESIN; STARCH; TABLET;

ALGORITHM; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; FRACTAL ANALYSIS; HUMIDITY; NUCLEAR MAGNETIC RESONANCE IMAGING; REAL TIME MAGNETIC RESONANCE IMAGING; RELATIVE DENSITY; TABLET DISINTEGRATION; TABLET MANUFACTURE; TABLET MATRIX; ANALOGS AND DERIVATIVES; CHEMISTRY; MEDICINAL CHEMISTRY; PROCEDURES; SOLUBILITY; TABLET;

CARBOXYMETHYLCELLULOSE SODIUM; CHEMISTRY, PHARMACEUTICAL; EXCIPIENTS; FRACTALS; MAGNETIC RESONANCE IMAGING; POVIDONE; RESINS, SYNTHETIC; SOLUBILITY; STARCH; TABLETS;

EID: 84908136006     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.09.021     Document Type: Article

References (25)

1. K. Block, and M. Uecker Simple method for adaptive gradient-delay compensation in radial MRI 19th Annual Meeting ISMRM Montreal, Quebec, Canada 2011
2. C. Caramella Novel methods for disintegrant characterization, part II Pharm. Technol. Int. 1990 30 37
3. C.R. Chen, Y.H. Lin, S.L. Cho, S.Y. Yen, and H.L.S. Wu Investigation of the dissolution difference between acidic and neutral media of acetaminophen tablets containing a super disintegrant and a soluble excipient Chem. Pharm. Bull. 45 1997 509 512
4. European Pharmacopoeia 8.1 E.P. Commission, Disintegration of Tablets and Capsules 2014 European Directorate for the Quality of Medicines (EDQM) Strasbourg, France 285 287
5. D. Gissinger, and A. Stamm A comparative evaluation of the properties of some tablets disintegrants Drug Dev. Ind. Pharm. 6 1980 511 536
6. M.S. Gordon, and Z.T. Chowhan The effect of aging on disintegrant efficiency in direct compression tablets with varied solubility and hygroscopicity, in terms of dissolution Drug Dev. Ind. Pharm. 16 1990 437 447
7. B.C. Hancock, J.T. Colvin, M.P. Mullarney, and A.V. Zinchuck The relative densities of pharmaceutical powders, blends, dry granulations, and immediate-release tablets Pharm. Technol. 27 2003 64 80
8. Q. Huang, J.R. Lorch, and R.C. Dubes Can the fractal dimension of images be measured? Pattern Recogn. 27 1994 339 349
9. Y. Iwao, S. Tanaka, T. Uchimoto, S. Noguchi, and S. Itai An easy-to-use approach for determining the disintegration ability of disintegrants by analysis of available surface area Int. J. Pharm. 448 2013 1 8
10. G. Jyothi, and P.K. Lakshmi Comparative evaluation of natural and synthetic superdisintegrants with newer superdisintegrant Kyron T-314 Acta Pharm. Sci. 53 2011 35 44
11. B.H. Kaye A Random Walk Trough Fractal Dimensions second ed. 1994 VCH Verlagsgesellschaft Weinheim, Germany
12. P.H. List, and U.A. Muazzam Quellung - die treibende kraft beim tablettenzerfall, 2 Mitteilung Pharm. Ind. 41 1979 1075 1077
13. B. Mandelbrot How long is the coast of Britain? Statistical self-similarity and fractional dimension Science 156 1967 636 638
14. X. Mesnier, T.O. Althaus, L. Forny, G. Niederreiter, S. Palzer, M.J. Hounslow, and A.D. Salman A novel method to quantify tablet disintegration Powder Technol. 238 2013 27 34
15. A. Moussavi, M. Untenberger, M. Uecker, and J. Frahm Correction of gradient-induced phase errors in radial MRI Magn. Reson. Med. 71 2014 308 312
16. N. Otsu Threshold selection methods from gray-level histograms IEEE Trans. Syst. Man Cyb. SMC 9 1979 62 66
17. J. Quodbach, A. Moussavi, R. Tammer, J. Frahm, and P. Kleinebudde Tablet disintegration studied by high-resolution real-time magnetic resonance imaging J. Pharm. Sci. 103 2014 249 255
18. E.M. Rudnic, C.T. Rhodes, S. Welch, and P. Bernardo Evaluations of the mechanism of disintegrant action Drug Dev. Ind. Pharm. 8 1982 87 109
19. U. Shah, and L. Augsburger Multiple sources of sodium starch glycolate, NF: evaluation of functional equivalence and development of standard performance tests Pharm. Dev. Technol. 7 2002 345 359
20. E. Shotton, and G.S. Leonard Effect of intra- and extra-granular maize starch on disintegration of compressed tablets J. Pharm. Pharmacol. 24 1972 798 803
21. M.S. Soumya Formulation and invitroevaluation of fast dissolving tablets of flecainide acetate Int. J. Pharm. Pharm. Sci. 5 2013 555 560
22. M. Uecker, S. Zhang, D. Voit, A. Karaus, K.-D. Merboldt, and J. Frahm Real-time MRI at a resolution of 20 ms NMR Biomed. 23 2010 986 994
23. E.W. Washburn The dynamics of capillary flow Phys. Rev. 17 1921 273
24. S. Zhang, K. Block, and J. Frahm Magnetic resonance imaging in real time: advances using radial FLASH J. Magn. Reson. Imag. 31 2010 101 109
25. N. Zhao, and L. Augsburger Functionality comparison of 3 classes of superdisintegrants in promoting aspirin tablet disintegration and dissolution AAPS PharmSciTech 6 2005