An easy-to-use approach for determining the disintegration ability of disintegrants by analysis of available surface area

International Journal of Pharmaceutics

Volumn 448, Issue 1, 2013, Pages 1-8

  Iwao, Yasunori ^a   Tanaka, Shoko ^a   Uchimoto, Takeaki ^a   Noguchi, Shuji ^a   Itai, Shigeru ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Available surface area; Disintegrant; Disintegration mechanism

Indexed keywords

CARBOXYMETHYLCELLULOSE CALCIUM; CROSCARMELLOSE SODIUM; CROSPOVIDONE; DISINTEGRATING AGENT; ETHENZAMIDE; LOW SUBSTITUTED HYDROXYPROPYLCELLULOSE; POVIDONE; STARCH GLYCOLATE SODIUM; UNCLASSIFIED DRUG;

ARTICLE; BODY SURFACE; CORRELATION ANALYSIS; DISSOLUTION; DRUG ANALYSIS; DRUG SOLUBILITY; PRIORITY JOURNAL; TABLET DISINTEGRATION; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET HARDNESS; TABLET SURFACE; WATER ABSORPTION;

ABSORPTION; CARBOXYMETHYLCELLULOSE SODIUM; CELLULOSE; EXCIPIENTS; POVIDONE; SALICYLAMIDES; SOLUBILITY; STARCH; SURFACE PROPERTIES; TABLETS; WATER;

EID: 84875641081     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.03.012     Document Type: Article

References (15)

1. A. Abdelbary, A.H. Elshafeey, and G. Zidan Comparative effects of different cellulosic based directly compressed orodispersable tablets on oral bioavailability of famotidine Carbohydr. Polym. 77 2009 799 806
2. Y. Agata, Y. Iwao, A. Miyagishima, and S. Itai Novel mathematical model for predicting the dissolution profile of spherical particles under non-sink conditions Chem. Pharm. Bull. 58 2010 511 515
3. Y. Bi, H. Sunada, Y. Yonezawa, K. Danjo, A. Otsuka, and K. Iida Preparation and evaluation of a compressed tablet rapidly disintegrating in the oral cavity Chem. Pharm. Bull. 44 1996 2121 2127 (Pubitemid 26396765)
4. C. Caramella, P. Colombo, U. Conte, A. Gazzaniga, and A. La Manna The role of swelling in the disintegration process Int. J. Pharm. Technol. Prod. Manuf. 5 1984 1 5
5. C. Caramella, P. Colombo, U. Conte, F. Ferrari, A. La Manna, H.V. Van Kamp, and G.K. Bolhuis Water uptake and disintegrating force measurements: towards a general understanding of disintegration mechanisms Drug Dev. Ind. Pharm. 12 1986 1749 1766 (Pubitemid 17178844)
6. C. Caramella, P. Colombo, U. Conte, F. Ferrari, A. Gazzaniga, A. La Manna, and N.A. Peppas A physical analysis of the phenomenon of tablet disintegration Int. J. Pharm. 44 1988 177 186
7. P. Colombo, C. Caramella, U. Conte, A. La Manna, A.M. Guyot Hermann, and J. Ringard Disintegrating force and tablet properties Drug Dev. Ind. Pharm. 7 1981 125 153
8. P. Colombo, C. Caramella, U. Conte, and N.A. Peppas Tablet disintegration: a physical model Proceedings Book of the 7th Pharmaceutical Technology Conference, vol. 3 London 1988 140 154
9. J. Fukami, E. Yonemochi, Y. Yoshihashi, and K. Terada Evaluation of rapidly disintegrating tablets containing glycine and carboxymethylcellulose Int. J. Pharm. 310 2006 101 109 (Pubitemid 43287972)
10. S. Itai, S. Kouchiwa, M. Nemoto, H. Murayama, and T. Nagai Effect of compression pressure and formulation on the available surface area of flufenamic acid in tablets Chem. Pharm. Bull. 34 1986 1264 1274 (Pubitemid 16103745)
11. J.L. Kanig, and E.M. Rudnic The mechanism of disintegrant action Pharm. Technol. 8 1984 50 62
12. S. Kouchiwa, M. Nemoto, S. Itai, H. Murayama, and T. Nagai Prediction of available surface area of powdered particles of flufenamic acid in tablets Chem. Pharm. Bull. 33 1985 1641 1651 (Pubitemid 15046094)
13. S. Schiermeier, and P.C. Schmidt Fast dispersible ibuprofen tablets Eur. J. Pharm. Sci. 15 2002 295 305 (Pubitemid 34229144)
14. T. Uchimoto, Y. Iwao, K. Takahashi, S. Tanaka, Y. Agata, T. Iwamura, A. Miyagishima, and S. Itai A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area Eur. J. Pharm. Biopharm. 72 2011 492 498
15. H.V. Van Kamp, G.K. Bolhuis, A.H. De Boer, C.F. Lerk, and L. Lie-A-Huen The role of water uptake on tablet disintegration Pharm. Acta Helv. 61 1986 22 29