Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines

Journal of Neurosurgery: Spine

Volumn 21, Issue 3, 2014, Pages 386-393

  Karikari, Isaac O ^a   Gilchrist, Christopher L ^b   Jing, Liufang ^b   Alcorta, David A ^d   Chen, Jun ^c   Richardson, William J ^c   Gabr, Mostafa A ^c   Bell, Richard D ^c   Kelley, Michael J ^d   Bagley, Carlos A ^a   Setton, Lori A ^b,c  

^a MS 101   (United States)

^b Duke University   (United States)

^c Departments of Orthopaedics   (United States)

^d DURHAM VA MEDICAL CENTER   (United States)

Author keywords

Brachyury; CD24; Chordoma; Oncology; U CH1; U CH2b; Xenograft

Indexed keywords

CD24 ANTIGEN; GENOMIC DNA; MESSENGER RNA; BRACHYURY; BRACHYURY PROTEIN; FETOPROTEIN; KERATIN; T BOX TRANSCRIPTION FACTOR; TUMOR MARKER;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CANCER GROWTH; CANCER SIZE; CARCINOGENESIS; CELL ISOLATION; CHORDOMA; COMPARATIVE STUDY; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NOD SCID GAMMA MOUSE; NONHUMAN; NUCLEUS PULPOSUS; PRIMARY CELL CULTURE; SACRUM; TISSUE SECTION; TUMOR CELL LINE; TUMOR XENOGRAFT; ANIMAL; BSA = BOVINE SERUM ALBUMIN; CD24; DISEASE MODEL; FBS = FETAL BOVINE SERUM; FITC = FLUORESCEIN ISOTHIOCYANATE; FLOW CYTOMETRY; IMDM = ISCOVE'S MODIFIED DULBECCO'S MEDIUM; METABOLISM; MFI = MEAN FLUORESCENCE INTENSITY; NSG = NOD/SCID/IL2RΓNULL; ONCOLOGY; PATHOLOGY; PBS = PHOSPHATE-BUFFERED SALINE; PCR = POLYMERASE CHAIN REACTION; POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; U-CH1; U-CH2B; XENOGRAFT;

BRACHYURY; BSA = BOVINE SERUM ALBUMIN; CD24; CHORDOMA; FBS = FETAL BOVINE SERUM; FITC = FLUORESCEIN ISOTHIOCYANATE; IMDM = ISCOVE'S MODIFIED DULBECCO'S MEDIUM; MFI = MEAN FLUORESCENCE INTENSITY; NSG = NOD/SCID/IL2RΓNULL; ONCOLOGY; PBS = PHOSPHATE-BUFFERED SALINE; PCR = POLYMERASE CHAIN REACTION; U-CH1; U-CH2B; XENOGRAFT;

AGED; ANIMALS; ANTIGENS, CD24; CELL LINE, TUMOR; CHORDOMA; DISEASE MODELS, ANIMAL; FETAL PROTEINS; FLOW CYTOMETRY; HETEROGRAFTS; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; MALE; MICE; POLYMERASE CHAIN REACTION; SACRUM; T-BOX DOMAIN PROTEINS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 84908129704     PISSN: 15475654     EISSN: 15475646     Source Type: Journal    
DOI: 10.3171/2014.4.SPINE13262     Document Type: Article

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