Extracorporeal treatment for barbiturate poisoning: Recommendations from the EXTRIP workgroup

American Journal of Kidney Diseases

Volumn 64, Issue 3, 2014, Pages 347-358

  Mactier, Robert ^a   Laliberté, Martin ^b   Mardini, Joelle ^c   Ghannoum, Marc ^c   Lavergne, Valery ^d   Gosselin, Sophie ^b   Hoffman, Robert S ^e   Nolin, Thomas D ^f  

^a NHS GREATER GLASGOW AND CLYDE   (United Kingdom)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Barbiturates; dialyzability; extracorporeal treatment; EXTRIP (Extracorporeal Treatments in Poisoning); hemodialysis; poisoning; recommendations

Indexed keywords

ACTIVATED CARBON; BARBITURIC ACID DERIVATIVE; LONG ACTING DRUG; SHORT ACTING DRUG;

ARTIFICIAL VENTILATION; CARDIOVASCULAR EFFECT; CENTRAL NERVOUS SYSTEM; CLINICAL ASSESSMENT; COMA; CONSENSUS; CONTINUOUS RENAL REPLACEMENT THERAPY; DELPHI STUDY; DIALYSATE; DRUG INTOXICATION; EVALUATION STUDY; EVIDENCE BASED PRACTICE; EXTRACORPOREAL TREATMENT; HEMODIALYSIS; HUMAN; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATION DEPRESSION; REVIEW; SHOCK; SYSTEMATIC REVIEW; THERAPY; TREATMENT INDICATION;

BARBITURATES; DIALYZABILITY; EXTRACORPOREAL TREATMENT; EXTRIP (EXTRACORPOREAL TREATMENTS IN POISONING); HEMODIALYSIS; POISONING; RECOMMENDATIONS;

BARBITURATES; HUMANS; POISONING; RENAL DIALYSIS;

EID: 84908123692     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2014.04.031     Document Type: Article

References (139)

1. A.C. Bronstein, D.A. Spyker, L.R. Cantilena Jr., J.L. Green, B.H. Rumack, and S.L. Giffin 2008 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 26th Annual Report Clin Toxicol (Phila) 47 10 2009 911 1084
2. J.B. Mowry, D.A. Spyker, L.R. Cantilena Jr., J.E. Bailey, and M. Ford 2012 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 30th Annual Report Clin Toxicol (Phila) 51 10 2013 949 1229
3. P. Botti, P. Garcia, B. Dannaoui, A. Ieri, and A. Pistelli Hemodialysis vs forced alkaline diuresis in acute barbiturate poisoning [abstract] Clin Toxicol (Phila) 42 4 2004 518
4. F.L. Cantrell, S. Nordt, I. McIntyre, and A. Schneir Death on the doorstep of a border community - intentional self-poisoning with veterinary pentobarbital Clin Toxicol (Phila) 48 8 2010 849 850
5. S. Srinivas, S. Karanth, and V. Nayyar Does it matter how we treat phenobarbitone overdose of moderate severity? Indian J Crit Care Med 8 2004 153 156
6. N. Morikawa, K. Mori, I. Fujii, and M. Takeyama Pharmacokinetic study in acute antiepileptic intoxication treated with hemodialysis and hemoperfusion [in Japanese] Jpn J Clin Pharmacol Ther 23 2 1992 469 474
7. O. Soylemezoglu, A. Bakkaloglu, S. Yigit, and U. Saatci Haemodialysis treatment in phenobarbital intoxication in infancy Int Urol Nephrol 25 1 1993 111 113
8. D.J. Quan, and M.E. Winter Extracorporeal removal of phenobarbital by high-flux hemodialysis J Appl Ther Res 2 1 1998 75 79
9. B.F. Palmer Effectiveness of hemodialysis in the extracorporeal therapy of phenobarbital overdose Am J Kidney Dis 36 3 2000 640 643
10. F. Jacobs, and F.G. Brivet Conventional haemodialysis significantly lowers toxic levels of phenobarbital Nephrol Dial Transplant 19 6 2004 1663 1664
11. R. Lal, S. Faiz, R.K. Garg, K.S. Baweja, J. Guntupalli, and K.W. Finkel Use of continuous venovenous hemodiafiltration in a case of severe phenobarbital poisoning Am J Kidney Dis 48 2 2006 e13 e15
12. T.M. Thompson, and S.E. Aks Case files of the toxikon medical toxicology fellowship in Chicago: the poisoned anesthesiologist J Med Toxicol 3 1 2007 31 36
13. Y. Kamijo, K. Soma, R. Kondo, and T. Ohwada Transient diffuse cerebral hypoperfusion in Tc-99m HMPAO SPECT of the brain during withdrawal syndrome following acute barbiturate poisoning Vet Human Toxicol 44 6 2002 348 350
14. A.W. Bouma, B. van Dam, I.A. Meynaar, H.G. Peltenburg, and M.C. Walenbergh-van Veen Accelerated elimination using hemoperfusion in a patient with phenobarbital intoxication [in Dutch] Ned Tijdschr Geneeskd 148 33 2004 1642 1645
15. J.L. Lin, and P.S. Lim Continuous arteriovenous hemoperfusion in acute poisoning Blood Purif 12 2 1994 121 127
16. D.M. Roberts, and N.A. Buckley Enhanced elimination in acute barbiturate poisoning - a systematic review Clin Toxicol (Phila) 49 1 2011 2 12
17. A. van de Plas, L. Stolk, M.A. Verhoeven, J.P. Kooman, and W.N. van Mook Successful treatment of acute phenobarbital intoxication by hemodiafiltration Clin Toxicol (Phila) 44 1 2006 93 94
18. E. Bironneau, F. Garrec, M.F. Kergueris, A. Testa, and F. Nicolas Hemodiafiltration in pentobarbital poisoning Ren Fail 18 2 1996 299 303
19. D.M. Roberts, A.M. Chau, P. Nair, and R.O. Day Enhanced elimination of phenobarbital using charcoal haemoperfusion in a patient with severe poisoning Br J Anaesth 107 5 2011 820 821
20. S.K. Agarwal, S.C. Tiwari, and S.C. Dash Spectrum of poisoning requiring haemodialysis in a tertiary care hospital in India Int J Artif Organs 16 1 1993 20 22
21. Hoyland K, Hoy M, Austin R, Wildman M. Successful use of haemodialysis to treat phenobarbital overdose [published online ahead of print November 21, 2013]. BMJ Case Rep. http://dx.doi.org/10.1136/bcr-2013-010011.
22. V. Lavergne, T.D. Nolin, and R.S. Hoffman et al. The EXTRIP (EXtracorporeal TReatments In Poisoning) workgroup: guideline methodology Clin Toxicol (Phila) 50 5 2012 403 413
23. S. Mihic, and R. Harris Chapter 17. Hypnotics and sedatives L.L. Brunton, B.A. Chabner, B.C. Knollmann, Goodman & Gilman's The Pharmacological Basis of Therapeutics 12th ed 2011 McGraw-Hill New York, NY 457 480
24. A. Doenicke General pharmacology of barbiturates. Duration of action, metabolism, physicochemical factors Acta Anaesthesiol Scand Suppl 17 1965 11 16
25. J. Bruni, and P.S. Albright The clinical pharmacology of antiepileptic drugs Clin Neuropharmacol 7 1 1984 1 34
26. D.D. Breimer Clinical pharmacokinetics of hypnotics Clin Pharmacokinet 2 2 1977 93 109
27. Sampson I. Barbiturates Mt Sinai J Med 50 4 1983 283 288
28. J.G. Setter, R.B. Freeman, J.F. Maher, and G.E. Schreiner Factors influencing the dialysis of barbiturates Trans Am Soc Artif Intern Organs 10 1964 340 344
29. M.J. Ferguson, and W.J. Grace The conservative management of barbiturate intoxication: experience with 95 unconscious patients Ann Intern Med 54 1961 726 733
30. G.E. Schreiner, and B.P. Teehan Dialysis of poisons and drugs - annual review Trans Am Soc Artif Intern Organs 17 1971 513 544
31. D.A. Boldy, J.A. Vale, and L.F. Prescott Treatment of phenobarbitone poisoning with repeated oral administration of activated charcoal Q J Med 61 235 1986 997 1002
32. A.H. Mohammed Ebid, and H.M. Abdel-Rahman Pharmacokinetics of phenobarbital during certain enhanced elimination modalities to evaluate their clinical efficacy in management of drug overdose Ther Drug Monit 23 3 2001 209 216
33. S.M. Pond, K.R. Olson, J.D. Osterloh, and T.G. Tong Randomized study of the treatment of phenobarbital overdose with repeated doses of activated charcoal JAMA 251 23 1984 3104 3108
34. P. Holzer, E. Beubler, and R. Dirnhofer Barbiturate poisoning and gastrointestinal propulsion Arch Toxicol 60 5 1987 394 396
35. A.T. Proudfoot, E.P. Krenzelok, and J.A. Vale Position paper on urine alkalinization J Toxicol Clin Toxicol 42 1 2004 1 26
36. M.L. Frenia, J.L. Schauben, R.L. Wears, J.L. Karlix, C.A. Tucker, and T.A. Kunisaki Multiple-dose activated charcoal compared to urinary alkalinization for the enhancement of phenobarbital elimination J Toxicol Clin Toxicol 34 2 1996 169 175
37. M. Ghannoum, T.D. Nolin, and D.S. Goldfarb et al. Extracorporeal treatment for thallium poisoning: recommendations from the EXTRIP Workgroup Clin J Am Soc Nephrol 7 10 2012 1682 1690
38. N. Alwall, and A. Lunderquist On the artificial kidney XXV. Dialytic treatment of severe barbiturate poisoning in two patients Acta Med Scand 147 2 1953 119 120
39. L.H. Kyle, H. Jeghers, W.P. Walsh, P.D. Doolan, H. Wishinsky, and A. Pallotta The application of hemodialysis to the treatment of barbiturate poisoning J Clin Invest 32 4 1953 364 371
40. I.A. Brown, J.S. Ansell, and B.C. Schiele The use of hemodialysis in the treatment of barbiturate intoxication Minn Med 37 9 1954 650 652
41. G. Gal, A. Nemeth, and I. Pinter Hemodialysis in the therapy of severe barbiturate poisoning [in Hungarian] Orv Hetil 97 21 1956 582
42. J.C. Pender, R.T. Beebe, J.J. Garrett, and J.E. Kiley Emergency treatment of barbiturate intoxication with hemodialysis Ann Intern Med 46 5 1957 997 1000
43. R.H. Balme, H.G. Lloyd-Thomas, and G.V. Shead Severe barbitone poisoning treated by haemodialysis Br Med J 1 5273 1962 231 232
44. J.F. Maher Hemodialysis and peritoneal dialysis; a review of their use in renal insufficiency and acute poisoning Ohio State Med J 60 1964 235 243
45. F. Duerr, and P. Glogner Osmotic diuresis, alkalotherapy and extracorporeal hemodialysis in the treatment of severe intoxication with hypnotics [in German] Med Welt 15 1965 755 756
46. W. Fritzer, H. Puxkandl, and W. Ratzenboeck Hemodialysis in the treatment of severe acute poisoning with sedatives [in German] Wien Z Inn Med 46 1965 72 79
47. D. Mullan, M. Platts, and B. Ridgway Barbiturate intoxication [letter] Lancet 1 7387 1965 705
48. H. Pogglitsch, and R. Zeichen On the use of extracorporeal hemodialysis in acute hypnotic poisoning [in German] Wien Med Wochenschr 115 1965 308 310
49. E.G. Whiting Jr., O. Barrett Jr., and T.W. Inmon Treatment of barbiturate poisoning. The use of peritoneal dialysis Calif Med 102 1965 367 369
50. W. Herms Therapeutic possibilities of exogenous poisoning with extracorporeal hemodialysis [in German] Dtsch Med Wochenschr 91 45 1966 2007 2013
51. M. Terplan, and A.M. Unger Survival following massive barbiturate ingestion JAMA 198 3 1966 322 323
52. J.O. Wieth Hemodialysis in barbiturate poisoning Int Anesthesiol Clin 4 2 1966 359 371
53. I.A. Cruz, N.C. Cramer, and A.E. Parrish Hemodialysis in chlordiazepoxide toxicity JAMA 202 5 1967 438 440
54. G.A. Rosland Hemodialysis in acute barbiturate poisoning [in Norwegian] Tidsskr Nor Laegeforen 87 1 1967 20 21
55. T.D. Bird, and F. Plum Recovery from barbiturate overdose coma with a prolonged isoelectric electroencephalogram Neurology 18 5 1968 456 460
56. S. Susa, E.P. Popovic, and B. Dumovic Successful treatment of babiturate coma by hemodialysis [in Serbian] Vojnosanit Pregl 25 5 1968 252 257
57. J.B. Hudson, A.J. Dennis Jr., D.R. Hobbs, and H.C. Sussman Extended hemodialysis in short acting barbiturate poisoning: case report South Med J 62 4 1969 457 460
58. G. Logi, G. Baldari, M. Rossi, and E. Fontana Extracorporeal dialysis in resuscitation in acute optalidon poisoning [in Italian] Acta Anaesthesiol 20 suppl 2 1969 39 48
59. J.L. Rosenbaum, S. Winsten, M.S. Kramuer, J. Moros, and R. Raja Resin hemoperfusion in the treatment of drug intoxication Trans Am Soc Artif Intern Organs 16 1970 134 140
60. R. Whang, M. Orndorff, and S. Papper Lipid-electrolyte ("lipo-lyte") dialysis - experimental and preliminary clinical observations Clin Toxicol 3 4 1970 551 560
61. Z. Falda, R. Polec, and M. Madalinska Tardyl poisoning treated with extracorporeal hemodialysis using rape-oil seed [in Polish] Pol Arch Med Wewn 47 2 1971 167 171
62. J.M. Mantz, J.D. Tempe, A. Jaeger, D. Kurtz, A. Lobstein, and G. Mack 24-Hour cerebral electric silence during a massive poisoning with 10g of pentobarbital. Hemodialysis cure [in French] Presse Med 79 27 1971 1243 1246
63. B.J. Hurwich, M. Goldstein, Y. Levi, and Y. Herishanu Successful 44-hour hemodialysis for multiple drug intoxication Isr J Med Sci 10 5 1974 495 497
64. E. Sorensen, and H. Baerentsen Dialysis treatment of barbiturate poisoning [in Danish] Ugeskr Laeger 136 30 1974 1687
65. R. Bosl, J.R. Shideman, R.M. Meyer, T.J. Buselmeier, B. von Hartitzsch, and C.M. Kjellstrand Effects and complications of high efficiency dialysis Nephron 15 2 1975 151 160
66. J. Puka, and J.M. Szajewski Case of exceptionally severe luminal poisoning (over 25 g) successfully treated with hemodialysis and forced diuresis [in Polish] Pol Tyg Lek 30 38 1975 1583 1585
67. A. Larcan, H. Lambert, and F. Ginsbourger Acute intoxication by phenformine hyperlactatemia reversible with extra-renal purification Vet Hum Toxicol 21 suppl 1979 19 22
68. E.T. Zawada Jr., J. Nappi, G. Done, and D. Rollins Advances in the hemodialysis management of phenobarbital overdose South Med J 76 1 1983 6 8
69. Z. Durakovic, and F. Plavsic Use of hemodialysis in the treatment of phenobarbitone and phenytoin poisoning [in Croatian] Arh Hig Rada Toksikol 37 1 1986 59 66
70. C. Bismuth, M. Gaultier, F. Conso, R. Assan, and C. Heuclin Lactic acidosis induced by excessive ingestion of metformin [in French] Eur J Toxicol Environ Hyg 9 1 1976 55 57
71. V.J. Musson Nursing care study: haemoperfusion in the treatment of severe barbiturate poisoning Nurs Times 72 50 1976 1956 1958
72. J.L. Rosenbaum, M.S. Kramer, R. Raja, S. Winsten, and F. Dalal Hemoperfusion for acute drug intoxication Kidney Int Suppl 10 7 1976 S341 S342
73. R. Voigtmann, H. von Baeyer, and H.G. Sieberth Charcoal-activated hemoperfusion - an important adjunct therapeutic method in severe poisoning [in German] Med Welt 27 16 1976 752 757
74. S. Arriagada Tapia, G. Martinez del Rio, and J. Llorente Herbach Barbiturate coma treated with peritoneal dialysis [in Spanish] Rev Chil Pediatr 49 1-6 1978 175 177
75. K.A. Jorgensen, K.N. Christensen, R.S. Pedersen, and N.A. Klitgaard Hemoperfusion in deliberate drug poisoning. Review and 2 case reports [in Danish] Ugeskr Laeger 140 17 1978 960 963
76. K.M. Knutsen, B. Skuterud, and S. Halvorsen Hemoperfusion in poisoning [in Norwegian] Tidsskr Nor Legeforen 99 3 1979 172 174
77. B. van Dijk, C.R. Vonk, and I.C. Dijkhuis Detoxification of toxic agents from the blood. Clinical results with a new hemoperfusion system: the Hemopur 260 [in Dutch] Tijdschr Ziekenverpl 32 16 1979 728 736
78. J.J. Garcia Perez, M.L. Mendez Perez, and M. Redondo Rodriguez et al. Treatment of acute drug poisoning with hemoperfusion through active coal and dialysis [in Spanish] Rev Clin Esp 156 6 1980 413 418
79. M. Helliwell Severe barbiturate and paracetamol overdose: the simultaneous removal of both poisons by haemoperfusion Postgrad Med J 56 655 1980 363 365
80. A. Trafford, C. Horn, P. Sharpstone, H. O'Neal, and R. Evans Hemoperfusion in acute drug toxicity Clin Toxicol 17 4 1980 547 556
81. G. Ciliberto, A.S. Corticelli, G.F. Di Nino, R. Rossi, and F. Petrini Clinical use of hemoperfusion over activated charcoal in cases of drug poisoning [in Italian] Riv Tossicol Sper Clin 12 4-6 1982 161 173
82. R. Bambauer, G.A. Jutzler, D. Stolz, and P. Doenecke Detoxication using a technically simplified plasma filtration system [in German] Intensivmed 19 2 1982 79 82
83. S.L. Cohan, J.F. Winchester, and M.C. Gelfand Treatment of intoxication with charcoal hemadsorption Drug Metab Rev 13 4 1982 681 693
84. S. Pond, P. Jacob III, M. Humphreys, R. Weiss, and T. Tong Impaired metabolism of methylphenobarbital after a combined drug overdose: treatment by resin hemoperfusion J Toxicol Clin Toxicol 19 2 1982 187 196
85. S. Raper, P. Crome, A. Vale, M. Helliwell, and B. Widdop Experience with activated carbon-bead haemoperfusion columns in the treatment of severe drug intoxication. A preliminary report Arch Toxicol 49 3-4 1982 303 310
86. P.A. Bjaeldager, L. Friberg, J.P. Kampmann, M.S. Christensen, and K. Jensen Hemoperfusion in severe barbiturate poisoning [in Danish] Ugeskr Laeger 145 47 1983 3653 3655
87. A.N. van Heijst, W. de Jong, R. Seldenrijk, and A. van Dijk Coma and crystalluria: a massive primidone intoxication treated with haemoperfusion J Toxicol Clin Toxicol 20 4 1983 307 318
88. K. Barber, S.M. Chen, R. Ferguson, M.S. Kramer, and R.M. Raja Lidocaine removal during resin hemoperfusion for phenobarbital intoxication Artif Organs 8 2 1984 229 231
89. J. Pach, B. Groszek, J. Brandys, and A. Negrusz Use of hemoperfusion in the treatment of acute poisoning with the preparation Reladorm [in Polish] Pol Tyg Lek 42 11 1987 333 334
90. K.H. Smolle, P. Kullnig, C. Logar, and H. Udermann Clinical assessment and therapy of barbiturate poisoning (based on 2 case reports) [in German] Wien Klin Wochenschr 99 22 1987 793 798
91. C. Bentley, and C.M. Kjellstrand The treatment of severe drug intoxication with charcoal hemoperfusion in series with hemodialysis J Dial 3 4 1979 337 348
92. W. Kirchmair Hemoperfusion and hemodialysis in severe poisoning with hypnotic drugs [in German] Munch Med Wschr 123 7 1981 231 232
93. J. Wehner, J. Arand, H. Todt, and K. Richter Phenobarbital poisoning in a eutrophic term newborn infant. A case report [in German] Kinderarztl Prax 59 1-2 1991 31 34
94. J.L. Lin, and L.B. Jeng Critical, acutely poisoned patients treated with continuous arteriovenous hemoperfusion in the emergency department Ann Emerg Med 25 1 1995 75 80
95. R. Sancak, S. Kucukoduk, H.A. Tasdemir, and N. Belet Exchange transfusion treatment in a newborn with phenobarbital intoxication Pediatr Emerg Care 15 4 1999 268 270
96. L.B. Berman, H.J. Jeghers, G.E. Schreiner, and A.J. Pallotta Hemodialysis, an effective therapy for acute barbiturate poisoning JAMA 161 9 1956 820 827
97. G.E. Schreiner The role of hemodialysis (artificial kidney) in acute poisoning AMA Arch Intern Med 102 6 1958 896 913
98. J. Landmann, R.M. Ribeiro, Y. Bedran, T. Vianna, and A. Gentile Treatment of acute barbiturate poisoning: dialysis by artificial kidney [in Portuguese] Med Cir Farm 21 276 1959 121 132
99. F. Del Greco, A.J. Arieff, and N.M. Simon Acute barbiturate and glutethimide intoxication. Management by hemodialysis and peritoneal dialysis Q Bull Northwest Univ Med Sch 36 1962 306 315
100. M. Kessel, K. Ibe, G. Neuhaus, H. Remmer, and H. Weller Extracorporeal dialysis of luminal [in German] Klin Wochenschr 40 1962 580 585
101. G.D. Lubash, M.J. Ferrari, L. Scherr, and A.L. Rubin Sedative overdosage and the role of hemodialysis Arch Intern Med 110 1962 884 887
102. H. Klinkmann, A. Huebel, A. Roehring, F. Scharz, H.J. Tredt, and K. Precht Hemodialysis in severe poisoning [in German] Dtsch Gesundheitsw 19 1964 60 66
103. A.L. Linton, R.G. Luke, I. Speirs, and A.C. Kennedy Forced diuresis and haemodialysis in severe barbiturate intoxication Lancet 1 7341 1964 1008 1010
104. G. Gal, A. Fazakas, and A. Nemeth Dialysis in the treatment of barbiturate poisoning [in German] Z Gesamte Inn Med 20 1965 304 307
105. J.G. Setter, J.F. Maher, and G.E. Schreiner Barbiturate intoxication. Evaluation of therapy including dialysis in a large series selectively referred because of severity Arch Intern Med 117 2 1966 224 236
106. A.C. Kennedy, J.D. Briggs, N. Young, R.M. Lindsay, R.G. Luke, and D. Campbell Successful treatment of three cases of very severe barbiturate poisoning Lancet 1 7603 1969 995 998
107. G. Stein, and W. Gerhardt Application of hemodialysis in exogenous poisoning [in German] Z Arztl Fortbild (Jena) 65 6 1971 296 301
108. A. Premel-Cabic, P. Alquier, R. Bonhomme, and P. Allain Study of barbiturate elimination during acute poisoning in man [in French] Therapie 28 5 1973 977 991
109. H. von Baeyer, H. Kunst, J. Freiberg, K.D. Grosser, and H.G. Sieberth Haemodialysis in intoxication with hypnotics [in German] Dtsch Med Wochenschr 99 5 1974 189 190
110. A. Sanz Guajardo, A. Montero Garcia, A. Aguado Matorras, M.A. Torre Carballada, and L. Sanchez Sicilia Value of hemodialysis in the treatment of acute poisoning by barbiturates [in Spanish] Rev Clin Esp 136 2 1975 147 152
111. R.S. Pedersen Barbiturate poisoning treated with hemodialysis [in Danish] Ugeskr Laeger 140 40 1978 2430 2432
112. S. Codina, R. Del Castillo, and J. Bartolome et al. Acute barbiturate poisoning and its treatment with hemodialysis [in Spanish] Rev Clin Esp 152 1 1979 25 26
113. A. Darnell, M. Garcia, E. Bergada, and L. Revert Long-term hemodialysis in acute barbiturate intoxication [in Spanish] Med Clin (Barc) 75 2 1980 49 53
114. J.L. Rosenbaum, M.S. Kramer, R. Raja, and C. Boreyko Resin hemoperfusion: a new treatment for acute drug intoxication N Engl J Med 284 15 1971 874 877
115. J.A. Vale, A.J. Rees, B. Widdop, and R. Goulding Use of charcoal haemoperfusion in the management of severely poisoned patients Br Med J 1 5948 1975 5 9
116. B.H. Barbour, A.M. LaSette, and A. Koffler Fixed-bed charcoal hemoperfusion for the treatment of drug overdose Kidney Int Suppl 10 7 1976 S333 S337
117. B. Grabensee, T. Konigshausen, and E. Schnurr Treatment of severe hypnotic poisoning with extracorporeal haemoperfusion [in German] Dtsch Med Wochenschr 101 5 1976 158 162
118. H. Hennemann, R. Naujoks, and W. Gattenlohner et al. Charcoal haemoperfusion in the treatment of sleeping-drug intoxication [in German] Dtsch Med Wochenschr 101 5 1976 155 158
119. G. de Groot, R.A. Maes, and A.N. van Heyst The use of haemoperfusion in the elimination of absorbed drug mixtures in acute intoxications Neth J Med 20 4-5 1977 142 148
120. M.C. Gelfand, J.F. Winchester, and J.H. Knepshield et al. Treatment of severe drug overdosage with charcoal hemoperfusion Trans Am Soc Artif Intern Organs 23 1977 599 605
121. L. Janos, O. Peter, H. Lajos, and L. Imre "Haemocol" hemoperfusion in the treatment of barbiturate poisoning [in Hungarian] Orv Hetil 118 5 1977 277 279
122. A. Koffler, M. Bernstein, A. LaSette, and S.G. Massry Fixed-bed charcoal hemoperfusion. Treatment of drug overdose Arch Intern Med 138 11 1978 1691 1694
123. J.A. Trafford, R.H. Jones, R. Evans, P. Sharp, P. Sharpstone, and J. Cook Haemoperfusion with R-004 Amberlite resin for treating acute poisoning Br Med J 2 6100 1977 1453 1456
124. G. de Groot, R.A. Maes, and A.N. van Heijst An evaluation of the use of hemoperfusion in acute poisoning Vet Hum Toxicol 21 suppl 1979 8 11
125. A. de Torrente, B.H. Rumack, D.T. Blair, and R.J. Anderson Fixed-bed uncoated charcoal hemoperfusion in the treatment of intoxications: animal and patient studies Nephron 24 2 1979 71 77
126. B.M. Iversen, Y. Willassen, O.M. Bakke, and G. Wallem Assessment of barbiturate removal by charcoal hemoperfusion in overdose cases Clin Toxicol 15 2 1979 139 149
127. C. Bismuth, and P.E. Fournier Biological evaluation of hemoperfusion in acute poisoning Dev Toxicol Environ Sci 8 1980 377 385
128. P. Crome, G. Hampel, B. Widdop, and R. Goulding Experience with cellulose acetate-coated activated charcoal haemoperfusion in the treatment of severe hypnotic drug intoxication Postgrad Med J 56 661 1980 763 766
129. M. Keusch-Beck, G. Keusch, F. Bammatter, H. Schiffl, P.C. Baumann, and U. Binswanger Hemoperfusion with activated charcoal in the treatment of drug overdose. Clinical experiences with 20 patients [in German] Schweiz Med Wochenschr 110 43 1980 1566 1575
130. C. Bismuth, P.E. Fournier, and M. Galliot Biological evaluation of hemoperfusion in acute poisoning Clin Toxicol 18 10 1981 1213 1223
131. R. Fantozzi, F. Martinelli, E. Masini, A. Sodi, L. Amaducci, and P. Mannaioni Use of haemoperfusion with uncoated charcoal in the management of acute intoxications with barbiturate and salicylate Subst Alcohol Actions Misuse 2 1 1981 55 62
132. G. Stein, U. Demme, and H. Sperschneider et al. Detoxication by hemoperfusion [in German] Z Gesamte Inn Med 36 24 1981 963 969
133. L.B. Berman, and P. Vogelsang Removal rates for barbiturates using two types of peritoneal dialysis N Engl J Med 270 1964 77 80
134. J.B. Hill, F.L. Palaia, J.L. McAdams, P.J. Palmer, and S.M. Maret Efficacy of activated charcoal hemoperfusion in removing lethal doses of barbiturates and salicylate from the blood of rats and dogs Clin Chem 22 6 1976 754 760
135. R. Sagraves, and J.C. Bradberry The effects of exchange transfusion on the pharmacokinetics of phenobarbital Drug Intell Clin Pharm 17 12 1983 901 903
136. I.S. Sketris, and W.A. Parker Verrier Jones J. Plasmapheresis: its effect on toxic agents and drugs Plasma Ther Transfus Technol 5 3 1984 305 317
137. C.W. Lai, I.E. Leppik, D.C. Jenkins, and P. Sood Epilepsy, myasthenia gravis, and effect of plasmapheresis on antiepileptic drug concentrations Arch Neurol 47 1 1990 66 68
138. J.G. Vale, E.P. Krenzelok, and V.D. Barceloux Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists J Toxicol Clin Toxicol 37 6 1999 731 751
139. M.W. Shannon Comparative efficacy of hemodialysis and hemoperfusion in severe theophylline intoxication Acad Emerg Med 4 7 1997 674 678