Circulating mycobacterial-reactive CD4+ T cells with an immunosuppressive phenotype are higher in active tuberculosis than latent tuberculosis infection

Tuberculosis

Volumn 94, Issue 5, 2014, Pages 494-501

  Kim, K ^a   Perera, R ^b   Tan, D B A ^c   Fernandez, S ^a   Seddiki, N ^d,e   Waring, J ^b   French, M A ^a,f  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b Tuberculosis Control Program Health Department of Western Australia   (Australia)

^c Lung Institute of Western Australia   (Australia)

^d INSERM U955   (France)

^e UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^f ROYAL PERTH HOSPITAL   (Australia)

Author keywords

Antigen reactive T cells; CD39; IL 10; Tuberculosis

Indexed keywords

CD134 ANTIGEN; CD39 ANTIGEN; CULTURE FILTRATE PROTEIN 10; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; APYRASE; BACTERIAL ANTIGEN; IFNG PROTEIN, HUMAN; IL10 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOREGULATION; IMMUNOSTIMULATION; INTERFERON GAMMA RELEASE ASSAY; LATENT TUBERCULOSIS; MALE; MYCOBACTERIUM TUBERCULOSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; T LYMPHOCYTE; TUBERCULOSIS; BLOOD; CELL CULTURE; COCULTURE; COMPARATIVE STUDY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHENOTYPE; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION;

ADULT; ANTIGENS, BACTERIAL; ANTIGENS, CD; APYRASE; CELLS, CULTURED; COCULTURE TECHNIQUES; FEMALE; HUMANS; IMMUNE TOLERANCE; IMMUNOPHENOTYPING; INTERFERON-GAMMA; INTERLEUKIN-10; LATENT TUBERCULOSIS; LYMPHOCYTE ACTIVATION; MALE; MYCOBACTERIUM TUBERCULOSIS; PHENOTYPE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84908123229     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2014.07.002     Document Type: Article

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