Photolytic degradation products of two highly brominated flame retardants cause cytotoxicity and mRNA expression alterations in chicken embryonic hepatocytes

Environmental Science and Technology

Volumn 48, Issue 20, 2014, Pages 12039-12046

  Su, Guanyong ^a   Letcher, Robert J ^a   Crump, Doug ^a   Farmahin, Reza ^a,b   Giesy, John P ^c,d,e   Kennedy, Sean W ^a,b  

^a CARLETON UNIVERSITY   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d MICHIGAN STATE UNIVERSITY   (United States)

^e CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BROMINE; FLAME RETARDANT; MESSENGER RNA; THYROID HORMONE; BROMOBENZENE; DECABROMOBIPHENYL ETHER; DIPHENYL ETHER DERIVATIVE; TETRADECABROMODIPHENOXYBENZENE;

CONCENTRATION (COMPOSITION); EMBRYO; GENE EXPRESSION; HORMONE; HYDROCARBON; METABOLISM; METHANOL; PHOTODEGRADATION; PHOTOLYSIS; POLYMERASE CHAIN REACTION; POULTRY; RADIATION BALANCE; RNA; TOXICITY;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CHOLESTEROL METABOLISM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; EMBRYO; GENE EXPRESSION; IMMUNE RESPONSE; IN VITRO STUDY; IRRADIATION; LIPID METABOLISM; LIVER CELL; NONHUMAN; OXIDATIVE STRESS; PHOTOCATALYSIS; POLYMERASE CHAIN REACTION; SUNLIGHT; ANIMAL; CELL CULTURE; CHICK EMBRYO; DOSE RESPONSE; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; HALOGENATION; METABOLISM; PHOTOLYSIS; PROCEDURES; TOXICITY TESTING;

ANIMALS; BROMOBENZENES; CELLS, CULTURED; CHICK EMBRYO; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLAME RETARDANTS; GENE EXPRESSION REGULATION; HALOGENATED DIPHENYL ETHERS; HALOGENATION; HEPATOCYTES; PHENYL ETHERS; PHOTOLYSIS; POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; SUNLIGHT; TOXICITY TESTS;

EID: 84908120106     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es503399r     Document Type: Article

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