Cytochrome P4501A induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and two chlorinated dibenzofurans in primary hepatocyte cultures of three avian species

Toxicological Sciences

Volumn 113, Issue 2, 2009, Pages 380-391

  Hervé, Jessica C ^a,b   Crump, Doug ^b   Jones, Stephanie P ^b   Mundy, Lukas J ^b   Giesy, John P ^c,d   Zwiernik, Matthew J ^c   Bursian, Steven J ^c   Jones, Paul D ^d   Wiseman, Steve B ^d   Wan, Yi ^d   Kennedy, Sean W ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b ENVIRONMENT CANADA   (Canada)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

AHR; Bird; EROD; Hepatocytes; PCDD; PCDF

Indexed keywords

2,3,4,7,8 PENTACHLORODIBENZOFURAN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,3,7,8 TETRACHLORODIBENZOFURAN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A4; CYTOCHROME P450 1A5; DIBENZOFURAN DERIVATIVE; ETHOXYRESORUFIN DEETHYLASE; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIRD; CHICKEN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DILUTION; EMBRYO; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; GENE EXPRESSION; IN VITRO STUDY; LIVER CELL CULTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; QUAIL; RING NECKED PHEASANT; SPECIES COMPARISON;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZOFURANS; BIRDS; CELLS, CULTURED; CHICKENS; COTURNIX; CYTOCHROME P-450 CYP1A1; ENZYME INDUCTION; GALLIFORMES; HEPATOCYTES; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN;

AVES; COTURNIX JAPONICA; GALLUS GALLUS; PHASIANUS COLCHICUS;

EID: 75249097324     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp270     Document Type: Article

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