Antioxidative activity and inhibition of key enzymes linked to type-2 diabetes (α-Glucosidase and α-Amylase) by khaya senegalensis

Acta Pharmaceutica

Volumn 64, Issue 3, 2014, Pages 311-324

  Ibrahim, Mohammed Auwal ^a,b   Koorbanally, Neil Anthony ^a   Islam, Md Shahidul ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b AHMADU BELLO UNIVERSITY   (Nigeria)

Author keywords

Khaya senegalensis (Meliaceae); oxidative stress; type 2 diabetes; amylase; glucosidase

Indexed keywords

ACETIC ACID ETHYL ESTER; ALCOHOL; ALPHA GLUCOSIDASE INHIBITOR; AMYLASE INHIBITOR; ANTIOXIDANT; ASCORBIC ACID; BUTANOL; CHROMONE DERIVATIVE; GALLIC ACID; KHAYA SENEGALENSIS LEAF EXTRACT; KHAYA SENEGALENSIS ROOT EXTRACT; KHAYA SENEGALENSIS STEM BARK EXTRACT; PLANT EXTRACT; TROLOX C; UNCLASSIFIED DRUG; WATER; ALPHA GLUCOSIDASE; AMYLASE; GLYCOSIDASE INHIBITOR; SCAVENGER; SOLVENT;

ANTIOXIDANT ACTIVITY; ARTICLE; BARK; BINDING AFFINITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DPPH RADICAL SCAVENGING ASSAY; DRUG DETERMINATION; ENZYME INHIBITION; IC50; KHAYA SENEGALENSIS; MASS FRAGMENTOGRAPHY; MEDICINAL PLANT; MELIACEAE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PLANT LEAF; PLANT ROOT; ANTAGONISTS AND INHIBITORS; CHEMISTRY; COMPARATIVE STUDY; DIABETES MELLITUS, TYPE 2; ENZYME SPECIFICITY; ENZYMOLOGY; FRACTIONATION; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; PHYTOTHERAPY;

ALPHA-AMYLASES; ALPHA-GLUCOSIDASES; BUTANOLS; CHEMICAL FRACTIONATION; DIABETES MELLITUS, TYPE 2; ETHANOL; FREE RADICAL SCAVENGERS; GLYCOSIDE HYDROLASE INHIBITORS; KINETICS; MELIACEAE; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; PLANT LEAVES; PLANT ROOTS; PLANTS, MEDICINAL; SOLVENTS; SUBSTRATE SPECIFICITY;

EID: 84908105972     PISSN: 13300075     EISSN: 18469558     Source Type: Journal    
DOI: 10.2478/acph-2014-0025     Document Type: Article

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