Comparison of olfactory bulbar and mucosal cultures in a rat rhizotomy model

Cell Transplantation

Volumn 23, Issue 11, 2014, Pages 1465-1470

  Ibrahim, Ahmed ^a   Li, Daqing ^a   Collins, Andrew ^a   Tabakow, Pawel ^b   Raisman, Geoffrey ^c   Li, Ying ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Dorsal roots; Olfactory ensheathing cells (OECs); Regeneration; Spinal cord injury; Transplants

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DORSAL ROOT; FEMALE; NERVE FIBER; NERVE REGENERATION; NONHUMAN; OLFACTORY BULB; OLFACTORY ENSHEATHING CELL; OLFACTORY EPITHELIUM; RAT; RHIZOTOMY; SPINAL CORD INJURY; ANIMAL; CELL CULTURE; CELL TRANSPLANTATION; CYTOLOGY; DISEASE MODEL; PATHOLOGY; PROCEDURES; SPINAL CORD INJURIES;

ANIMALS; CELL TRANSPLANTATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; OLFACTORY BULB; OLFACTORY MUCOSA; RATS; RHIZOTOMY; SPINAL CORD INJURIES;

EID: 84908103297     PISSN: 09636897     EISSN: 15553892     Source Type: Journal    
DOI: 10.3727/096368913X676213     Document Type: Article

References (26)

1. Bareyre, F. M.; Kerschensteiner, M.; Raineteau, O.; Mettenleiter, T. C.; Weinmann, O.; Schwab, M. E. The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nat. Neurosci. 7:269-277; 2004.
2. Barnett, S. C.; Hutchins, A.-M.; Noble, M. Purification of olfactory nerve ensheathing cells from the olfactory bulb. Dev. Biol. 155:337-350; 1993.
3. Bianco, J. I.; Perry, C.; Harkin, D. G.; Mackay-Sim, A.; Féron, F. Neurotrophin 3 promotes purification and proliferation of olfactory ensheathing cells from human nose. Glia 45:111-123; 2004.
4. Cavalieri, S.; Cazzaniga, S.; Geuna, M.; Magnani, Z.; Bordignon, C.; Naldini, L.; Bonini, C. Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence. Blood 102:497-505; 2003.
5. Czyz, M.; Tabakow, P.; Gheek, D.; Mis, M.; Jarmundowicz, W.; Raisman, G. The supraorbital keyhole approach via an eyebrow incision applied to obtain the olfactory bulb as a source of olfactory ensheathing cells-Radiological feasibility study. Br. J. Neurosurg. 28:234-240; 2014.
6. Féron, F.; Perry, C.; Cochrane, J.; Licina, P.; Nowitzke, A.; Urquhart, S.; Geraghty, T.; Mackay-Sim, A. Autologous olfactory ensheathing cell transplantation in human spinal cord injury. Brain 128:2951-2960; 2005.
7. Ibrahim, A. G.; Kirkwood, P. A.; Raisman, G.; Li, Y. Resto­ ration of hand function in a rat model of repair of brachial plexus injury. Brain 132:1268-1276; 2009.
8. Ibrahim, A. G.; Raisman, G.; Li, Y. Permanent loss of forepaw grasping requires complete deprivation of afferent input from a minimum of four dorsal roots of the rat brachial plexus. Exp. Neurol. 215:142-145; 2009.
9. Jani, H. R.; Raisman, G. Ensheathing cell cultures from the olfactory bulb and mucosa. Glia 47:130-137; 2004.
10. Keyvan-Fouladi, N.; Raisman, G.; Li, Y. Functional repair of the corticospinal tract by delayed transplantation of olfactory ensheathing cells in adult rats. J. Neurosci. 23: 9428-9434; 2003.
11. Kueh, J. L.; Raisman, G.; Li, Y.; Stevens, R.; Li, D. Comparison of bulbar and mucosal olfactory ensheathing cells using FACS and simultaneous antigenic bivariate cell cycle analysis. Glia 59:1658-1671; 2011.
12. Li, Y.; Decherchi, P.; Raisman, G. Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing. J. Neurosci. 23:727-731; 2003.
13. Li, Y.; Field, P. M.; Raisman, G. Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells. Science 277:2000-2002; 1997.
14. Li, Y.; Field, P. M.; Raisman, G. Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells. J. Neurosci. 18:10514-10524; 1998.
15. Li, Y.; Li, D.; Khaw, P. T.; Raisman, G. Transplanted olfactory ensheathing cells incorporated into the optic nerve head ensheath retinal ganglion cell axons: Possible relevance to glaucoma. Neurosci. Lett. 440:251-254; 2008.
16. Mayeur, A.; Duclos, C.; Honore, A.; Gauberti, M.; Drouot, L.; do Rego, J. C.; Bon-Mardion, N.; Jean, L.; Verin, E.; Emery, E.; Lemarchant, S.; Vivien, D.; Boyer, O.; Marie, J. P.; Guerout, N. Potential of olfactory ensheathing cells from different sources for spinal cord repair. PLoS One 8:e62860; 2013.
17. Naldini, L.; Blomer, U.; Gallay, P.; Ory, D.; Mulligan, R.; Gage, F. H.; Verma, I. M.; Trono, D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272:263-267; 1996.
18. Raineteau, O.; Fouad, K.; Bareyre, F. M.; Schwab, M. E. Reorganization of descending motor tracts in the rat spinal cord. Eur. J. Neurosci. 16:1761-1771; 2002.
19. Ramón-Cueto, A.; Valverde, F. Olfactory bulb ensheathing glia: A unique cell type with axonal growth-promoting properties. Glia 14:163-173; 1995.
20. Rubio, M. P.; Munoz-Quiles, C.; Ramon-Cueto, A. Adult olfactory bulbs from primates provide reliable ensheathing glia for cell therapy. Glia 56:539-551; 2008.
21. Ruitenberg, M. J.; Plant, G. W.; Christensen, C. L.; Blits, B.; Niclou, S. P.; Harvey, A. R.; Boer, G. J.; Verhaagen, J. Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord. Gene Ther. 9:135-146; 2002.
22. Steward, O.; Sharp, K.; Selvan, G.; Hadden, A.; Hofstadter, M.; Au, E.; Roskams, J. A re-assessment of the consequences of delayed transplantation of olfactory lamina propria following complete spinal cord transection in rats. Exp. Neurol. 198:483-499; 2006.
23. Tabakow, P.; Jarmundowicz, W.; Czapiga, B.; Fortuna, W.; Miedzybrodzki, R.; Czyz, M.; Huber, J.; Szarek, D.; Okurowski, S.; Szewczyk, P.; Gorski, A.; Raisman, G. Transplantation of autologous olfactory ensheathing cells in complete human spinal cord injury. Cell Transplant. 22:1591-1612; 2013.
24. Tabakow, P.; Raisman, G.; Fortuna, W.; Czyz, M.; Huber, J.; Li, D.; Szewczyk, P.; Okurowski, S.; Miedzybrodzki, R.; Czapiga, B.; Salomon, B.; Halon, A.; Li, Y.; Lipiec, J.; Kulczyk, A.; Jarmundowicz, W. Functional regeneration of supraspinal connections in a patient with transected spinal cord following transplantation of bulbar olfactory ensheathing cells with peripheral nerve bridging. Cell Transplant. E-pub available on-line: October 21, 2014.
25. Yamamoto, M.; Raisman, G.; Li, D.; Li, Y. Transplanted olfactory mucosal cells restore paw reaching function with out regeneration of severed corticospinal tract fibres across the lesion. Brain Res. 1303:26-31; 2009.
26. Ziegler, M. D.; Hsu, D.; Takeoka, A.; Zhong, H.; Ramon Cueto, A.; Phelps, P. E.; Roy, R. R.; Edgerton, V. R. Further evidence of olfactory ensheathing glia facilitating axonal regeneration after a complete spinal cord transection. Exp. Neurol. 229:109-119; 2011.