OncomiR-196 promotes an invasive phenotype in oral cancer through the NME4-JNK-TIMP1-MMP signaling pathway

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Lu, Ya Ching ^a   Chang, Joseph T ^b   Liao, Chun Ta ^b   Kang, Chung Jan ^b   Huang, Shiang Fu ^b   Chen, I How ^b   Huang, Chi Che ^b   Huang, Yu Chen ^b   Chen, Wen Ho ^b   Tsai, Chi Ying ^b   Wang, Hung Ming ^b   Yen, Tzu Chen ^b   You, Guo Rung ^a   Chiang, Chang Hsu ^a   Cheng, Ann Joy ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Cell invasion; Clinical association; JNK signaling; miR 196; NME4; Oral cancer

Indexed keywords

ANTAGOMIR; GELATINASE B; INTERSTITIAL COLLAGENASE; METALLOPROTEINASE; MICRORNA; MICRORNA 196A; MICRORNA 196B; NUCLEOSIDE DIPHOSPHATE KINASE D; STRESS ACTIVATED PROTEIN KINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG; MATRIX METALLOPROTEINASE; MIRN196 MICRORNA, HUMAN; NME4 PROTEIN, HUMAN; TIMP1 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER THERAPY; CANCER TISSUE; CELL FUNCTION; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL SURVIVAL; CHEMOSENSITIVITY; CONFOCAL MICROSCOPY; ENZYME PHOSPHORYLATION; FEMALE; GENE CONTROL; GENE OVEREXPRESSION; GENETIC ALGORITHM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; LOSS OF FUNCTION MUTATION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; MOUTH CANCER; ONCOGENE; ORAL CANCER CELL LINE; PHENOTYPE; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR INVASION; WESTERN BLOTTING; CANCER STAGING; CELL MOTION; CELL PROLIFERATION; ENZYMOLOGY; GENETICS; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; MOUTH TUMOR; NUCLEOTIDE SEQUENCE; PATHOLOGY; TUMOR CELL LINE;

ADULT; AGED; BASE SEQUENCE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MATRIX METALLOPROTEINASES; MICRORNAS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; NUCLEOSIDE DIPHOSPHATE KINASE D; PHENOTYPE; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 84908093401     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-218     Document Type: Article

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