Reduced cortisol metabolism during critical illness

New England Journal of Medicine

Volumn 368, Issue 16, 2013, Pages 1477-1488

  Boonen, Eva ^a   Vervenne, Hilke ^a   Meersseman, Philippe ^b   Andrew, Ruth ^d   Mortier, Leen ^c   Declercq, Peter E ^c   Vanwijngaerden, Yoo Mee ^a   Spriet, Isabel ^b   Wouters, Pieter J ^a   Vander Perre, Sarah ^a   Langouche, Lies ^a   Vanhorebeek, Ilse ^a   Walker, Brian R ^d   Van Den Berghe, Greet ^a  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c JESSA HOSPITAL   (Belgium)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTISOL METABOLIZING ENZYME; HYDROCORTISONE; MESSENGER RNA; UNCLASSIFIED DRUG; UNCLASSIFIED ENZYME;

ADULT; ARTICLE; CONTROLLED STUDY; CORTICOSTEROID METABOLISM; CORTICOTROPIN BLOOD LEVEL; CRITICAL ILLNESS; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE URINE LEVEL; HYPERCORTISOLISM; INTENSIVE CARE UNIT; LIVER BIOPSY; MAJOR CLINICAL STUDY; MALE; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEROIDOGENESIS; UPREGULATION;

EID: 84876316462     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1214969     Document Type: Article

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